Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Dec 10; Vol. 18 (1), pp. 288. Date of Electronic Publication: 2021 Dec 10.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions.

Authors : Porcher L; Pharmacology, Physiology & Neuroscience, University of South Carolina School of Medicine, 6439 Garners Ferry Rd, Columbia, SC, 29209, USA.; Bruckmeier S

Subjects: Sex Characteristics*; Aging/Aging/Aging/*immunology ; Cytokines/Cytokines/Cytokines/*biosynthesis

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Sep 22; Vol. 18 (1), pp. 219. Date of Electronic Publication: 2021 Sep 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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MD2 contributes to the pathogenesis of perioperative neurocognitive disorder via the regulation of α5GABA A receptors in aged mice.

Authors : Zuo W; Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, Air Force Medical University, Xi'an, 710032, China.; Zhao J

Subjects: Aging/Aging/Aging/*metabolism ; Lymphocyte Antigen 96/Lymphocyte Antigen 96/Lymphocyte Antigen 96/*biosynthesis ; Neurocognitive Disorders/Neurocognitive Disorders/Neurocognitive Disorders/*metabolism

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Sep 16; Vol. 18 (1), pp. 204. Date of Electronic Publication: 2021 Sep 16.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Acute inflammatory profiles differ with sex and age after spinal cord injury.

Authors : Stewart AN; Department of Physiology, Spinal Cord and Brain Injury Research Center, University of Kentucky College of Medicine, Lexington, KY, 40536, USA.; Lowe JL

Subjects: Aging* ; Sex Characteristics*; Acute-Phase Reaction/Acute-Phase Reaction/Acute-Phase Reaction/*metabolism

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 May 13; Vol. 18 (1), pp. 113. Date of Electronic Publication: 2021 May 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Age influences susceptibility of brain capillary endothelial cells to La Crosse virus infection and cell death.

Authors : Basu R; Research and Technologies Branch, Rocky Mountain Laboratories, NIAID, NIH, 903 S. 4th Street, MT, 59840, Hamilton, USA.; Signaling Systems Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4 Memorial Drive, Bethesda, MD, 20892, USA.

Subjects: Aging* ; Cell Death*; Blood-Brain Barrier/Blood-Brain Barrier/Blood-Brain Barrier/*virology

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Jun 03; Vol. 18 (1), pp. 125. Date of Electronic Publication: 2021 Jun 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Sirtuin 3 protects against anesthesia/surgery-induced cognitive decline in aged mice by suppressing hippocampal neuroinflammation.

Authors : Liu Q; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Tongshan Road 209, Xuzhou, 221004, P.R. China.; Sun YM

Subjects: Aging/Aging/Aging/*metabolism ; Anesthetics, Inhalation/Anesthetics, Inhalation/Anesthetics, Inhalation/*toxicity ; Hippocampus/Hippocampus/Hippocampus/*metabolism

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Feb 04; Vol. 18 (1), pp. 41. Date of Electronic Publication: 2021 Feb 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration.

Authors : Lee KS; Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, BS8 1TD, UK.; Lin S

Subjects: Aging* ; Cellular Senescence* ; Macular Degeneration*

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Jan 22; Vol. 18 (1), pp. 32. Date of Electronic Publication: 2021 Jan 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Comparisons of neuroinflammation, microglial activation, and degeneration of the locus coeruleus-norepinephrine system in APP/PS1 and aging mice.

Authors : Cao S; Department of Pain Medicine, Affiliated Hospital of Zunyi Medical University, 149 Dalian Street, Zunyi, 563000, Guizhou, China.; Guizhou Key Lab of Anesthesia and Organ Protection, Affiliated Hospital of Zunyi Medical University, 6 West Xuefu Street, Zunyi, 563002, Guizhou, China.

Subjects: Amyloid beta-Protein Precursor*/Amyloid beta-Protein Precursor*/Amyloid beta-Protein Precursor*/genetics ; Presenilin-1*/Presenilin-1*/Presenilin-1*/genetics; Aging/Aging/Aging/*metabolism

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Jan 06; Vol. 18 (1), pp. 10. Date of Electronic Publication: 2021 Jan 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia.

Authors : Malone K; Department of Pharmacology and Therapeutics, Western Gateway Building, University College Cork, Cork, Ireland.; School of Pharmacy, University College Cork, Cork, Ireland.

Subjects: Disease Models, Animal*; Aging/Aging/Aging/*drug effects ; Brain Ischemia/Brain Ischemia/Brain Ischemia/*drug therapy

Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Jan 30; Vol. 18 (1), pp. 37. Date of Electronic Publication: 2021 Jan 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Substantia nigra Smad3 signaling deficiency: relevance to aging and Parkinson's disease and roles of microglia, proinflammatory factors, and MAPK.

Authors : Liu Y; Department of Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, P.R. China.; Yu L

Subjects: Aging/Aging/Aging/*metabolism ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*physiology ; Microglia/Microglia/Microglia/*metabolism

Source: Journal of neuroinflammation [J Neuroinflammation] 2020 Nov 16; Vol. 17 (1), pp. 342. Date of Electronic Publication: 2020 Nov 16.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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