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Temporal changes in regulatory T cell subsets defined by the transcription factor Helios in stroke and their potential role in stroke-associated infection: a prospective case–control study

• Authors : Maria Lukasik; Magdalena Telec; Radoslaw Kazmierski

Subjects: Regulatory T cells; Transcription factor Helios; Stroke

• Source: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)

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SIRPα modulates microglial efferocytosis and neuroinflammation following experimental subarachnoid hemorrhage via the SHP1/STAT6 axis.

• Authors : Zhang B; Department of Neurosurgery, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.; Zou Y

Subjects: Subarachnoid Hemorrhage*/Subarachnoid Hemorrhage*/Subarachnoid Hemorrhage*/metabolism ; Subarachnoid Hemorrhage*/Subarachnoid Hemorrhage*/Subarachnoid Hemorrhage*/pathology ; Protein Tyrosine Phosphatase, Non-Receptor Type 6*/Protein Tyrosine Phosphatase, Non-Receptor Type 6*/Protein Tyrosine Phosphatase, Non-Receptor Type 6*/metabolism

• Source: Journal of neuroinflammation [J Neuroinflammation] 2025 Mar 19; Vol. 22 (1), pp. 88. Date of Electronic Publication: 2025 Mar 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Inhibition of neutrophil extracellular traps alleviates blood-brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy.

• Authors : Yue J; Joint Project of Pinnacle Disciplinary Group, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Subjects: Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/metabolism ; Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/drug effects ; Extracellular Traps*/Extracellular Traps*/Extracellular Traps*/metabolism

• Source: Journal of neuroinflammation [J Neuroinflammation] 2025 Mar 18; Vol. 22 (1), pp. 87. Date of Electronic Publication: 2025 Mar 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Alterations of the IKZF1-IKZF2 tandem in immune cells of schizophrenia patients regulate associated phenotypes.

• Authors : Ballasch I; Departament de Biomedicina, Facultat de Medicina, Institut de Neurociències, Universitat de Barcelona, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036, Barcelona, Spain.

Subjects: Ikaros Transcription Factor*/Ikaros Transcription Factor*/Ikaros Transcription Factor*/genetics ; Ikaros Transcription Factor*/Ikaros Transcription Factor*/Ikaros Transcription Factor*/metabolism ; Schizophrenia*/Schizophrenia*/Schizophrenia*/genetics

• Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Dec 18; Vol. 21 (1), pp. 326. Date of Electronic Publication: 2024 Dec 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer's disease mice.

• Authors : Liu M; Institute of Laboratory Animal Science, CAMS & Comparative Medicine Center, PUMC, Beijing, China.; National Human Diseases Animal Model Resource Center, Beijing, China.

Subjects: STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/metabolism ; STAT3 Transcription Factor*/STAT3 Transcription Factor*/STAT3 Transcription Factor*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism

• Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Nov 01; Vol. 21 (1), pp. 282. Date of Electronic Publication: 2024 Nov 01.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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α-Synuclein disrupts microglial autophagy through STAT1-dependent suppression of Ulk1 transcription.

• Authors : Pei CS; Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu, China.; Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience, Soochow University, Suzhou, Jiangsu, 215123, China.

Subjects: Autophagy-Related Protein-1 Homolog*/Autophagy-Related Protein-1 Homolog*/Autophagy-Related Protein-1 Homolog*/metabolism ; Autophagy-Related Protein-1 Homolog*/Autophagy-Related Protein-1 Homolog*/Autophagy-Related Protein-1 Homolog*/genetics ; alpha-Synuclein*/alpha-Synuclein*/alpha-Synuclein*/metabolism

• Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Oct 26; Vol. 21 (1), pp. 275. Date of Electronic Publication: 2024 Oct 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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PEDF-34 attenuates neurological deficit and suppresses astrocyte-dependent neuroinflammation by modulating astrocyte polarization via 67LR/JNK/STAT1 signaling pathway after subarachnoid hemorrhage in rats.

• Authors : Wu L; Department of Cerebrovascular Surgery, Neurosurgery Center, Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, Guangdong, China.; Department of Physiology and Pharmacology, Basic Sciences, School of Medicine, Loma Linda University, Loma Linda, CA, 92354, USA.

Subjects: Astrocytes*/Astrocytes*/Astrocytes*/drug effects ; Astrocytes*/Astrocytes*/Astrocytes*/metabolism ; Nerve Growth Factors*/Nerve Growth Factors*/Nerve Growth Factors*/metabolism

• Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Jul 21; Vol. 21 (1), pp. 178. Date of Electronic Publication: 2024 Jul 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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FoxP3 expression by retinal pigment epithelial cells: transcription factor with potential relevance for the pathology of age-related macular degeneration

• Authors : Ahmad Samir Alfaar; Lucas Stürzbecher; Maria Diedrichs-Möhring

Subjects: IL-1β; Ca-channels; CRISPR/Cas9

• Source: Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-23 (2022)

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Inhibition of IL-6 trans-signaling promotes post-stroke functional recovery in a sex and dose-dependent manner.

• Authors : Hall C; Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA.; Nguyen DT

Subjects: Interleukin-6*/Interleukin-6*/Interleukin-6*/metabolism ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Signal Transduction*/Signal Transduction*/Signal Transduction*/physiology

• Source: Journal of neuroinflammation [J Neuroinflammation] 2025 Feb 26; Vol. 22 (1), pp. 52. Date of Electronic Publication: 2025 Feb 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia

• Authors : Horiuchi, Makoto; Wakayama, Kouji; Itoh, Aki

• Source: Journal of Neuroinflammation. 9(1)

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