Search Results

Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema.

• Authors : Savaskan NE; Brain Research Institute, Swiss Federal Institute of Technology & University Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.; Heckel A

Subjects: Gene Silencing*; Amino Acid Transport System y+/Amino Acid Transport System y+/Amino Acid Transport System y+/*genetics ; Brain Edema/Brain Edema/Brain Edema/*pathology

• Source: Nature medicine [Nat Med] 2008 Jun; Vol. 14 (6), pp. 629-32. Date of Electronic Publication: 2008 May 11.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet

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Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS

• Authors : Bravo-Hernandez, Mariana; Tadokoro, Takahiro; Navarro, Michael R

Subjects: Medical Biotechnology; Biomedical and Clinical Sciences; ALS

• Source: Nature Medicine. 26(1)

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A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy.

• Authors : Zhang, Ge¹; Guo, Baosheng¹; Wu, Heng¹

• Source: Nature Medicine. Feb2012, Vol. 18 Issue 2, p307-314. 8p. 1 Color Photograph, 4 Graphs.

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In vivo imaging of siRNA delivery and silencing in tumors.

• Authors : Medarova, Zdravka¹; Pham, Wellington¹; Farrar, Christian¹

• Source: Nature Medicine. Mar2007, Vol. 13 Issue 3, p372-377. 6p.

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5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.

• Authors : Poeck H; Institute of Clinical Chemistry and Pharmacology, University Hospital, University of Bonn, Bonn, Germany.; Besch R

Subjects: Gene Silencing*; DEAD-box RNA Helicases/DEAD-box RNA Helicases/DEAD-box RNA Helicases/*metabolism ; Melanoma/Melanoma/Melanoma/*genetics

• Source: Nature medicine [Nat Med] 2008 Nov; Vol. 14 (11), pp. 1256-63. Date of Electronic Publication: 2008 Nov 02.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.

• Authors : Hornung V; Department of Internal Medicine, Division of Clinical Pharmacology, Ludwig-Maximilians-University of Munich, Ziemssenstr. 1, 80336 München, Germany.; Guenthner-Biller M

Subjects: Dendritic Cells/Dendritic Cells/Dendritic Cells/*immunology ; Interferon-alpha/Interferon-alpha/Interferon-alpha/*biosynthesis ; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*physiology

• Source: Nature medicine [Nat Med] 2005 Mar; Vol. 11 (3), pp. 263-70. Date of Electronic Publication: 2005 Feb 20.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Print

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Sensing the danger in RNA.

• Authors : Robbins MA; Rossi JJ

Subjects: RNA Interference*; Dendritic Cells/Dendritic Cells/Dendritic Cells/*immunology ; Interferon Type I/Interferon Type I/Interferon Type I/*biosynthesis

• Source: Nature medicine [Nat Med] 2005 Mar; Vol. 11 (3), pp. 250-1.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Print ISSN:

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RNA interference targeting Fas protects mice from fulminant hepatitis.

• Authors : Song E; Center for Blood Research and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.; Lee SK

Subjects: RNA Interference*; Hepatitis, Autoimmune/Hepatitis, Autoimmune/Hepatitis, Autoimmune/*prevention & control ; Hepatitis, Autoimmune/Hepatitis, Autoimmune/Hepatitis, Autoimmune/*therapy

• Source: Nature medicine [Nat Med] 2003 Mar; Vol. 9 (3), pp. 347-51. Date of Electronic Publication: 2003 Feb 10.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Print

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Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells.

• Authors : Ptasznik A; Division of Hematology/Oncology, Department of Medicine and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. ; Nakata Y

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Blast Crisis/Blast Crisis/Blast Crisis/*metabolism ; Fusion Proteins, bcr-abl/Fusion Proteins, bcr-abl/Fusion Proteins, bcr-abl/*metabolism

• Source: Nature medicine [Nat Med] 2004 Nov; Vol. 10 (11), pp. 1187-9. Date of Electronic Publication: 2004 Oct 24.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Print

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PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression

• Authors : Horiuchi, Dai; Camarda, Roman; Zhou, Alicia Y

Subjects: Biomedical and Clinical Sciences; Oncology and Carcinogenesis; Cancer

• Source: Nature Medicine. 22(11)

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