Authors : Lanzillotta C; Department of Biochemical Sciences A. Rossi Fanelli, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.; Baniowska MR

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/genetics ; Down Syndrome*/Down Syndrome*/Down Syndrome*/pathology ; Down Syndrome*/Down Syndrome*/Down Syndrome*/metabolism

Source: Neurobiology of disease [Neurobiol Dis] 2024 Jun 15; Vol. 196, pp. 106523. Date of Electronic Publication: 2024 May 04.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Sex-specific developmental alterations in DYRK1A expression in the brain of a Down syndrome mouse model.

Authors : Hawley LE; Department of Biology, Indiana University - Purdue University Indianapolis, 723 W. Michigan Street, SL306, Indianapolis, IN, 46202, USA.; Stringer M

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/genetics ; Down Syndrome*/Down Syndrome*/Down Syndrome*/metabolism; Animals

Source: Neurobiology of disease [Neurobiol Dis] 2024 Jan; Vol. 190, pp. 106359. Date of Electronic Publication: 2023 Nov 20.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Investigating brain alterations in the Dp1Tyb mouse model of Down syndrome.

Authors : Serrano ME; Department of Neuroimaging, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.; Kim E

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/pathology; Male ; Female

Source: Neurobiology of disease [Neurobiol Dis] 2023 Nov; Vol. 188, pp. 106336.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print Cited Medium: Internet ISSN: 1095-953X

Record details

Read More Add to Saved list

Academic Journal

Maternal choline supplementation protects against age-associated cholinergic and GABAergic basal forebrain neuron degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

Authors : Gautier MK; Center for Dementia Research, Nathan Kline Institute, Orangeburg, NY, USA; Pathobiology and Translational Medicine Program, New York University Grossman School of Medicine, New York, NY, USA

Subjects: Down Syndrome* ; Alzheimer Disease* ; Basal Forebrain*

Source: Neurobiology of disease [Neurobiol Dis] 2023 Nov; Vol. 188, pp. 106332. Date of Electronic Publication: 2023 Oct 26.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Increased propensity for infantile spasms and altered neocortical excitation-inhibition balance in a mouse model of down syndrome carrying human chromosome 21.

Authors : Shao LR; Division of Pediatric Neurology, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: .; Gao F

Subjects: Spasms, Infantile*/Spasms, Infantile*/Spasms, Infantile*/genetics ; Down Syndrome*/Down Syndrome*/Down Syndrome*/genetics ; Neocortex*

Source: Neurobiology of disease [Neurobiol Dis] 2023 Aug; Vol. 184, pp. 106198. Date of Electronic Publication: 2023 Jun 13.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Postnatal environmental enrichment enhances memory through distinct neural mechanisms in healthy and trisomic female mice.

Authors : Alemany-González M; Integrative Pharmacology and Systems Neuroscience, Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, 08003 Barcelona, Spain.; Vilademunt M

Subjects: Down Syndrome* ; Intellectual Disability*; Animals

Source: Neurobiology of disease [Neurobiol Dis] 2022 Oct 15; Vol. 173, pp. 105841. Date of Electronic Publication: 2022 Aug 18.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice.

Authors : Ahmed MM; Department of Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; University of Colorado Alzheimer's and Cognition Center, Aurora, CO 80045, USA

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Down Syndrome*/Down Syndrome*/Down Syndrome*/drug therapy

Source: Neurobiology of disease [Neurobiol Dis] 2022 Jun 15; Vol. 168, pp. 105694. Date of Electronic Publication: 2022 Mar 18.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome.

Authors : Tramutola A; Department of Biochemical Sciences 'A. Rossi-Fanelli', Sapienza University of Rome, Piazzale A. Moro 5, 00185 Roma, Italy.; Lanzillotta C

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Brain/Brain/Brain/*metabolism ; Down Syndrome/Down Syndrome/Down Syndrome/*metabolism

Source: Neurobiology of disease [Neurobiol Dis] 2020 Apr; Vol. 137, pp. 104772. Date of Electronic Publication: 2020 Jan 24.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Inhibitory designer receptors aggravate memory loss in a mouse model of down syndrome.

Authors : Hamlett ED; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address: .; Ledreux A

Subjects: Adrenergic Neurons/Adrenergic Neurons/Adrenergic Neurons/*metabolism ; Down Syndrome/Down Syndrome/Down Syndrome/*metabolism ; Locus Coeruleus/Locus Coeruleus/Locus Coeruleus/*metabolism

Source: Neurobiology of disease [Neurobiol Dis] 2020 Feb; Vol. 134, pp. 104616. Date of Electronic Publication: 2019 Oct 31.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list

Academic Journal

Obstructive sleep apneas naturally occur in mice during REM sleep and are highly prevalent in a mouse model of Down syndrome.

Authors : Bartolucci ML; Section of Orthodontics, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy; PRISM Lab, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy.

Subjects: Down Syndrome/Down Syndrome/Down Syndrome/*physiopathology ; Sleep Apnea, Central/Sleep Apnea, Central/Sleep Apnea, Central/*physiopathology ; Sleep Apnea, Obstructive/Sleep Apnea, Obstructive/Sleep Apnea, Obstructive/*physiopathology

Source: Neurobiology of disease [Neurobiol Dis] 2021 Nov; Vol. 159, pp. 105508. Date of Electronic Publication: 2021 Sep 10.Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list