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Academic Journal

High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination.

Subjects: *SMALL interfering RNA; *RNA interference; *GOLDEN hamster

  • Source: Nucleic Acids Research. 1/13/2025, Vol. 53 Issue 1, p1-13. 13p.

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Academic Journal

Enhanced RNAi does not provide efficient innate antiviral immunity in mice.

Subjects: *SMALL interfering RNA; *LYMPHOCYTIC choriomeningitis virus; *RNA interference

  • Source: Nucleic Acids Research. 1/13/2025, Vol. 53 Issue 1, p1-18. 18p.

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Academic Journal

Structural basis of endo-siRNA processing by Drosophila Dicer-2 and Loqs-PD.

  • Authors : Cao N; Ministry of Education Key Laboratory of Protein Sciences, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Frontier Research Center of Biological Structures, State Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.; Wang J

Subjects: Ribonuclease III*/Ribonuclease III*/Ribonuclease III*/metabolism ; Ribonuclease III*/Ribonuclease III*/Ribonuclease III*/chemistry ; Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Feb 08; Vol. 53 (4).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

An AT-hook transcription factor promotes transcription of histone, spliced-leader, and piRNA clusters.

  • Authors : Wang YH; Department of Biological Chemistry and Pharmacology, The Ohio State University, Columbus, OH 43210, United States.; Center for RNA Biology, The Ohio State University, Columbus, OH 43210, United States.

Subjects: Histones*/Histones*/Histones*/metabolism ; Histones*/Histones*/Histones*/genetics ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Feb 08; Vol. 53 (4).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Quantifying the activity profile of ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo.

Subjects: *GLIOBLASTOMA multiforme; *NUCLEIC acids; *UNSATURATED fatty acids

  • Source: Nucleic Acids Research. 5/22/2024, Vol. 52 Issue 9, p4799-4817. 19p.

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Academic Journal

A combinatorial approach for achieving CNS-selective RNAi.

Subjects: *RNA interference; *SMALL interfering RNA; *GENE silencing

  • Source: Nucleic Acids Research. 5/22/2024, Vol. 52 Issue 9, p5273-5284. 12p.

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Academic Journal

Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo.

Subjects: *SMALL interfering RNA; *CHIRALITY; *ISOMERS

  • Source: Nucleic Acids Research. 2/22/2022, Vol. 50 Issue 3, p1221-1240. 20p.

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Academic Journal

The SARS-CoV-2 nucleocapsid protein interferes with the full enzymatic activation of UPF1 and its interaction with UPF2.

Subjects: *SMALL interfering RNA; *RNA interference; *VIRUS diseases

  • Source: Nucleic Acids Research. 1/27/2025, Vol. 53 Issue 2, p1-14. 14p.

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Academic Journal

Cre-Lox miRNA-delivery technology optimized for inducible microRNA and gene-silencing studies in zebrafish.

Subjects: *RNA interference; *SMALL interfering RNA; *SPINAL muscular atrophy

  • Source: Nucleic Acids Research. 1/27/2025, Vol. 53 Issue 2, p1-13. 13p.

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Academic Journal

Selecting genes for analysis using historically contingent progress: from RNA changes to protein–protein interactions.

Subjects: *RNA interference; *SMALL interfering RNA; *CAENORHABDITIS elegans

  • Source: Nucleic Acids Research. 1/13/2025, Vol. 53 Issue 1, p1-16. 16p.

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  • 1-10 of  1,371 results for ""Small Interfering""