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Academic Journal

Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB.

  • Authors : Tsatsanis C; Department of Microbiology and Immunology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.; Patriotis C

Subjects: MAP Kinase Kinase Kinases* ; Mitogen-Activated Protein Kinase Kinases* ; Mitogen-Activated Protein Kinases*

  • Source: Oncogene [Oncogene] 1998 Nov 19; Vol. 17 (20), pp. 2609-18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Cot protooncoprotein activates the dual specificity kinases MEK-1 and SEK-1 and induces differentiation of PC12 cells.

  • Authors : Hagemann D; Institut für la Medizinische Strahlenkunde und Zellforschung, University of Würzburg, Germany.; Troppmair J

Subjects: Cell Differentiation* ; MAP Kinase Kinase Kinases* ; Mitogen-Activated Protein Kinase Kinases*

  • Source: Oncogene [Oncogene] 1999 Feb 18; Vol. 18 (7), pp. 1391-400.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Negative regulation of MEKK1/2 signaling by serine-threonine kinase 38 (STK38).

  • Authors : Enomoto A; Section of Radiation Biology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. ; Kido N

Subjects: Gene Expression Regulation* ; Signal Transduction*; MAP Kinase Kinase Kinase 1/MAP Kinase Kinase Kinase 1/MAP Kinase Kinase Kinase 1/*metabolism

  • Source: Oncogene [Oncogene] 2008 Mar 20; Vol. 27 (13), pp. 1930-8. Date of Electronic Publication: 2007 Oct 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer.

  • Authors : Zhan Y; Department of Biological Sciences, University of Toledo, Toledo, OH, USA.; Modi N

Subjects: MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/*metabolism ; Neoplasms/Neoplasms/Neoplasms/*pathology ; Neurofibromin 2/Neurofibromin 2/Neurofibromin 2/*metabolism

  • Source: Oncogene [Oncogene] 2011 Feb 17; Vol. 30 (7), pp. 781-9. Date of Electronic Publication: 2010 Oct 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

TAK1 is required for TGF-beta 1-mediated regulation of matrix metalloproteinase-9 and metastasis.

  • Authors : Safina A; Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.; Ren MQ

Subjects: Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*enzymology ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*secondary ; MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/*physiology

  • Source: Oncogene [Oncogene] 2008 Feb 21; Vol. 27 (9), pp. 1198-207. Date of Electronic Publication: 2007 Sep 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Physical and functional interaction of the TPL2 kinase with nucleophosmin.

  • Authors : Kanellis DC; 1] Molecular and Cellular Biology Laboratory, Division of Basic Sciences, University of Crete Medical School, Heraklion, Greece [2] Laboratory of Cancer Biology, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas (FORTH), Heraklion, Greece.; Bursac S

Subjects: Active Transport, Cell Nucleus/Active Transport, Cell Nucleus/Active Transport, Cell Nucleus/*radiation effects ; MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

  • Source: Oncogene [Oncogene] 2015 May 07; Vol. 34 (19), pp. 2516-26. Date of Electronic Publication: 2014 Jul 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.

  • Authors : Garner AP; Inositide Laboratory, Signalling Programme, The Babraham Institute, Babraham Hall, Cambridge CB2 4AT, UK.; Weston CR

Subjects: CDC2-CDC28 Kinases*; Fibroblasts/Fibroblasts/Fibroblasts/*cytology ; G2 Phase/G2 Phase/G2 Phase/*physiology

  • Source: Oncogene [Oncogene] 2002 Nov 21; Vol. 21 (53), pp. 8089-104.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034.

  • Authors : Fujii K; Department of Pharmacology, Emory University School of Medicine, Atlanta GA 30322, USA.; Goldman EH

Subjects: MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/*metabolism; Apoptosis ; Humans

  • Source: Oncogene [Oncogene] 2004 Jun 24; Vol. 23 (29), pp. 5099-104.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Ras stimulates DNA topoisomerase II alpha through MEK: a link between oncogenic signaling and a therapeutic target.

  • Authors : Chen G; Department of Molecular Biology, Cleveland Clinic Foundation, OH 44195, USA.; Templeton D

Subjects: DNA Topoisomerases, Type II*/DNA Topoisomerases, Type II*/DNA Topoisomerases, Type II*/*metabolism; DNA Topoisomerases, Type II*/DNA Topoisomerases, Type II*/DNA Topoisomerases, Type II*/genetics ; MAP Kinase Kinase Kinase 1*

  • Source: Oncogene [Oncogene] 1999 Nov 25; Vol. 18 (50), pp. 7149-60.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1).

  • Authors : Hoeflich KP; Department of Medical Biophysics, Ontario Cancer Institute, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.; Yeh WC

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/MAP Kinase Kinase Kinases/*physiology ; Proteins/Proteins/Proteins/*metabolism

  • Source: Oncogene [Oncogene] 1999 Oct 14; Vol. 18 (42), pp. 5814-20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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