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Integrating multiscale mathematical modeling and multidimensional data reveals the effects of epigenetic instability on acquired drug resistance in cancer.

• Authors : Wang, Shun¹ (AUTHOR); Lei, Jinzhi² (AUTHOR); Zou, Xiufen¹ (AUTHOR)

• Source: PLoS Computational Biology. 2/14/2025, Vol. 21 Issue 2, p1-24. 24p.

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Epigenetic cell memory: The gene’s inner chromatin modification circuit

• Authors : Bruno, Simone; Williams, Ruth J; Del Vecchio, Domitilla

Subjects: Biochemistry and Cell Biology; Biological Sciences; Genetics

• Source: PLOS Computational Biology. 18(4)

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Phenotypic pliancy and the breakdown of epigenetic polycomb mechanisms.

• Authors : Lambros, Maryl¹ (AUTHOR); Sella, Yehonatan¹ (AUTHOR); Bergman, Aviv^1,2,3,4 (AUTHOR)

• Source: PLoS Computational Biology. 2/21/2023, Vol. 19 Issue 2, p1-22. 22p. 4 Graphs.

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Dynamical modeling of the H3K27 epigenetic landscape in mouse embryonic stem cells.

• Authors : Newar, Kapil¹ (AUTHOR); Abdulla, Amith Zafal² (AUTHOR); Salari, Hossein² (AUTHOR)

• Source: PLoS Computational Biology. 9/2/2022, Vol. 18 Issue 9, p1-31. 31p. 2 Diagrams, 2 Charts, 4 Graphs.

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Novel feature selection methods for construction of accurate epigenetic clocks.

• Authors : Li, Adam¹ (AUTHOR); Mueller, Amber¹ (AUTHOR); English, Brad¹ (AUTHOR)

• Source: PLoS Computational Biology. 8/19/2022, Vol. 18 Issue 8, p1-18. 18p. 1 Diagram, 4 Charts, 3 Graphs.

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High fidelity epigenetic inheritance: Information theoretic model predicts threshold filling of histone modifications post replication.

• Authors : Ramakrishnan, Nithya¹ (AUTHOR); Pillai, Sibi Raj B.² (AUTHOR) ; Padinhateeri, Ranjith¹ (AUTHOR)

• Source: PLoS Computational Biology. 2/17/2022, Vol. 18 Issue 2, p1-22. 22p. 1 Color Photograph, 2 Diagrams, 3 Graphs.

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The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function.

• Authors : Battistini, Federica¹ (AUTHOR); Dans, Pablo D.^1,2,3 (AUTHOR); Terrazas, Montserrat¹ (AUTHOR)

• Source: PLoS Computational Biology. 11/8/2021, Vol. 17 Issue 11, p1-24. 24p. 4 Diagrams, 2 Charts, 4 Graphs.

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Epigenetic instability may alter cell state transitions and anticancer drug resistance.

• Authors : Saini, Anshul¹ (AUTHOR); Gallo, James M.¹ (AUTHOR)

• Source: PLoS Computational Biology. 8/23/2021, Vol. 17 Issue 8, p1-15. 15p. 3 Diagrams, 1 Chart, 3 Graphs.

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A Statistical Framework to Identify Deviation from Time Linearity in Epigenetic Aging.

• Authors : Snir, Sagi; vonHoldt, Bridgett M; Pellegrini, Matteo

Subjects: Animals; Humans; DNA

• Source: PLoS computational biology. 12(11)

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Bivalent chromatin as a therapeutic target in cancer: An in silico predictive approach for combining epigenetic drugs.

• Authors : Alarcón, Tomás^1,2,3 (AUTHOR) ; Sardanyés, Josep² (AUTHOR); Guillamon, Antoni^2,4,5 (AUTHOR)

• Source: PLoS Computational Biology. 6/21/2021, Vol. 17 Issue 6, p1-25. 25p. 3 Diagrams, 5 Graphs.

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