Search Results

Estimating the number of genetic mutations (hits) required for carcinogenesis based on the distribution of somatic mutations.

• Authors : Anandakrishnan, Ramu^1,2 ; Varghese, Robin T.^1,2; Kinney, Nicholas A.^1,2

• Source: PLoS Computational Biology. 3/7/2019, Vol. 15 Issue 3, p1-19. 19p. 2 Diagrams, 1 Chart, 4 Graphs.

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Estimating the number of genetic mutations (hits) required for carcinogenesis based on the distribution of somatic mutations.

• Authors : Ramu Anandakrishnan; Robin T Varghese; Nicholas A Kinney

Subjects: Biology (General); QH301-705.5

• Source: PLoS Computational Biology, Vol 15, Iss 3, p e1006881 (2019)

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A novel hypergraph model for identifying and prioritizing personalized drivers in cancer.

• Authors : Zhang, Naiqian¹ (AUTHOR) ; Ma, Fubin¹ (AUTHOR); Guo, Dong^1,2 (AUTHOR)

• Source: PLoS Computational Biology. 4/29/2024, Vol. 20 Issue 4, p1-23. 23p.

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Differential allelic representation (DAR) identifies candidate eQTLs and improves transcriptome analysis.

• Authors : Baer, Lachlan¹ (AUTHOR); Barthelson, Karissa^1,2 (AUTHOR); Postlethwait, John H.³ (AUTHOR)

• Source: PLoS Computational Biology. 2/12/2024, Vol. 20 Issue 2, p1-27. 27p.

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Identification of key somatic oncogenic mutation based on a confounder-free causal inference model.

• Authors : Liu, Yijun¹ (AUTHOR); Sun, Ji¹ (AUTHOR); Sun, Huiyan^1,2 (AUTHOR)

• Source: PLoS Computational Biology. 9/22/2022, Vol. 18 Issue 9, p1-19. 19p. 2 Diagrams, 3 Charts, 6 Graphs.

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A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants.

• Authors : Kernik, Divya C.¹ (AUTHOR); Yang, Pei-Chi¹ (AUTHOR); Kurokawa, Junko² (AUTHOR)

• Source: PLoS Computational Biology. 8/14/2020, Vol. 16 Issue 8, p1-28. 28p. 3 Charts, 8 Graphs.

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G2Φnet: Relating genotype and biomechanical phenotype of tissues with deep learning.

• Authors : Zhang, Enrui¹ (AUTHOR); Spronck, Bart² (AUTHOR); Humphrey, Jay D.³ (AUTHOR)

• Source: PLoS Computational Biology. 10/31/2022, Vol. 18 Issue 10, p1-23. 23p. 2 Diagrams, 4 Graphs.

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Dynamic coupling of residues within proteins as a mechanistic foundation of many enigmatic pathogenic missense variants.

• Authors : Ose, Nicholas J.¹ (AUTHOR); Butler, Brandon M.¹ (AUTHOR); Kumar, Avishek¹ (AUTHOR)

• Source: PLoS Computational Biology. 4/7/2022, Vol. 18 Issue 4, p1-22. 22p. 1 Chart, 4 Graphs.

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CoRE-ATAC: A deep learning model for the functional classification of regulatory elements from single cell and bulk ATAC-seq data.

• Authors : Thibodeau, Asa¹ (AUTHOR); Khetan, Shubham¹ (AUTHOR); Eroglu, Alper¹ (AUTHOR)

• Source: PLoS Computational Biology. 12/13/2021, Vol. 17 Issue 12, p1-32. 32p. 1 Diagram, 3 Charts, 4 Graphs.

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Evolution of phenotypic fluctuation under host-parasite interactions.

• Authors : Nishiura, Naoto¹ (AUTHOR); Kaneko, Kunihiko^1,2 (AUTHOR)

• Source: PLoS Computational Biology. 11/9/2021, Vol. 17 Issue 11, p1-22. 22p. 1 Chart, 8 Graphs.

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