Search Results

Trajectory-centric framework TrajAtlas reveals multi-scale differentiation heterogeneity among cells, genes, and gene modules in osteogenesis.

• Authors : Han L; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, China.; Ji Y

Subjects: Osteogenesis*/Osteogenesis*/Osteogenesis*/genetics ; Cell Differentiation*/Cell Differentiation*/Cell Differentiation*/genetics ; Osteoblasts*/Osteoblasts*/Osteoblasts*/metabolism

• Source: PLoS genetics [PLoS Genet] 2024 Oct 22; Vol. 20 (10), pp. e1011319. Date of Electronic Publication: 2024 Oct 22 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

Record details

Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice.

• Authors : Zhou, Xin¹; von der Mark, Klaus²; Henry, Stephen¹

• Source: PLoS Genetics. Dec2014, Vol. 10 Issue 12, p1-20. 20p.

Record details

Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

• Authors : Xin Qin; Qing Jiang; Kenichi Nagano

Subjects: Male; Vascular Endothelial Growth Factor A; 0301 basic medicine

• Source: PLoS GenetPLoS Genetics, Vol 16, Iss 11, p e1009169 (2020)

Record details

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density.

• Authors : Swan AL; Schütt C ...

Subjects: Bone Density/Bone Density/Bone Density/*genetics ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*genetics ; Osteoblasts/Osteoblasts/Osteoblasts/*metabolism

• Source: PLoS genetics [PLoS Genet] 2020 Dec 28; Vol. 16 (12), pp. e1009190. Date of Electronic Publication: 2020 Dec 28 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

Record details

Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass.

• Authors : Doolittle ML; Center for Musculoskeletal Research, University of Rochester, Rochester, New York, United States of America.; Calabrese GM

Subjects: Bone Density/Bone Density/Bone Density/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*physiology ; Osteoblasts/Osteoblasts/Osteoblasts/*metabolism

• Source: PLoS genetics [PLoS Genet] 2020 Jun 04; Vol. 16 (6), pp. e1008805. Date of Electronic Publication: 2020 Jun 04 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

Record details

The DNA Helicase Recql4 Is Required for Normal Osteoblast Expansion and Osteosarcoma Formation.

• Authors : Ng, Alvin J. M.^1,2; Walia, Mannu K.¹; Smeets, Monique F.¹

• Source: PLoS Genetics. Apr2015, Vol. 11 Issue 4, p1-25. 25p.

Record details

Mouse genome-wide association and systems genetics identifies Lhfp as a regulator of bone mass.

• Authors : Mesner LD; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, United States of America.; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, United States of America.

Subjects: Genome* ; Quantitative Trait Loci*; Bone and Bones/Bone and Bones/Bone and Bones/*metabolism

• Source: PLoS genetics [PLoS Genet] 2019 May 01; Vol. 15 (5), pp. e1008123. Date of Electronic Publication: 2019 May 01 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

Record details

Systems Genetic Analysis of Osteoblast-Lineage Cells.

• Authors : Calabrese, Gina¹; Bennett, Brian J.²; Orozco, Luz³

• Source: PLoS Genetics. Dec2012, Vol. 8 Issue 12, p1-18. 18p.

Record details

Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica.

• Authors : Chan WL; Institut für Medizinische Genetik und Humangenetik, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; FG Development & Disease, Max-Planck-Institut fuer Molekulare Genetik, Berlin, Germany.

Subjects: Bone Diseases/Bone Diseases/Bone Diseases/*congenital ; Dwarfism/Dwarfism/Dwarfism/*metabolism ; Osteoblasts/Osteoblasts/Osteoblasts/*pathology Gerodermia osteodysplastica

• Source: PLoS genetics [PLoS Genet] 2018 Mar 21; Vol. 14 (3), pp. e1007242. Date of Electronic Publication: 2018 Mar 21 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

Record details

mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway.

• Authors : Huang B; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China.; Wang Y

Subjects: Cell Differentiation*; Multiprotein Complexes/Multiprotein Complexes/Multiprotein Complexes/*physiology ; Osteoblasts/Osteoblasts/Osteoblasts/*physiology

• Source: PLoS genetics [PLoS Genet] 2015 Aug 04; Vol. 11 (8), pp. e1005426. Date of Electronic Publication: 2015 Aug 04 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

Record details