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Dehydroepiandrosterone inhibits ADAMTS expression via an ERK-dependent mechanism in chondrocytes.

• Authors : Huang K; Department of Orthopedic Surgery, Tongde Hospital of Zhejiang Province, Hangzhou, China.; Cheng L

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/drug effects ; Dehydroepiandrosterone*/Dehydroepiandrosterone*/Dehydroepiandrosterone*/pharmacology

• Source: PloS one [PLoS One] 2024 Nov 22; Vol. 19 (11), pp. e0313560. Date of Electronic Publication: 2024 Nov 22 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery.

• Authors : Coryell PR; Thurston Arthritis Research Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.; Hardy PB

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/drug effects ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/metabolism

• Source: PloS one [PLoS One] 2024 Nov 01; Vol. 19 (11), pp. e0308647. Date of Electronic Publication: 2024 Nov 01 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Mume Fructus reduces interleukin-1 beta-induced cartilage degradation via MAPK downregulation in rat articular chondrocytes.

• Authors : Park DR; Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Gangnam-gu, Seoul, Republic of Korea.; Choi BR

Subjects: Cartilage, Articular*/Cartilage, Articular*/Cartilage, Articular*/drug effects ; Cartilage, Articular*/Cartilage, Articular*/Cartilage, Articular*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/drug effects

• Source: PloS one [PLoS One] 2024 May 08; Vol. 19 (5), pp. e0302906. Date of Electronic Publication: 2024 May 08 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Human umbilical cord mesenchymal stem cells decellular matrix alleviates chondrocyte senescence by inhibiting the STING-NF-κB pathway.

• Authors : Zhang Y; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, China.; Ren X

Subjects: NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/cytology ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism

• Source: PloS one [PLoS One] 2025 Jun 26; Vol. 20 (6), pp. e0325704. Date of Electronic Publication: 2025 Jun 26 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Human fetal cartilage-derived chondrocytes and chondroprogenitors display a greater commitment to chondrogenesis than adult cartilage resident cells.

• Authors : Vinod E; Department of Physiology, Christian Medical College, Vellore, India.; Centre for Stem Cell Research, (A Unit of InStem, Bengaluru), Christian Medical College, Vellore, India.

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; Cartilage, Articular*/Cartilage, Articular*/Cartilage, Articular*/metabolism; Humans

• Source: PloS one [PLoS One] 2023 Apr 27; Vol. 18 (4), pp. e0285106. Date of Electronic Publication: 2023 Apr 27 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Retraction: Effects of UCP4 on the proliferation and apoptosis of chondrocytes: Its possible involvement and regulation in osteoarthritis.

• Authors : PLOS ONE Editors

• Source: PloS one [PLoS One] 2025 May 07; Vol. 20 (5), pp. e0324041. Date of Electronic Publication: 2025 May 07 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Epstein-Barr virus-induced gene 3 commits human mesenchymal stem cells to differentiate into chondrocytes via endoplasmic reticulum stress sensor.

• Authors : Zhang T; First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan.; Yamagata K

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/cytology ; Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/Endoplasmic Reticulum Stress*/genetics ; Interleukins*/Interleukins*/Interleukins*/genetics

• Source: PloS one [PLoS One] 2022 Dec 22; Vol. 17 (12), pp. e0279584. Date of Electronic Publication: 2022 Dec 22 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Protective effects of ectoine on articular chondrocytes and cartilage in rats for treating osteoarthritis.

• Authors : Li, Peng^1,2 (AUTHOR) ; Huang, Yong² (AUTHOR); Miao, Lishuai² (AUTHOR)

Subjects: *Articular cartilage; *Cartilage; *Reactive oxygen species

• Source: PLoS ONE. 2/29/2024, Vol. 19 Issue 2, p1-16. 16p.

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Intermittent hypoxic stimulation promotes efficient expression of Hypoxia-inducible factor-1α and exerts a chondroprotective effect in an animal osteoarthritis model.

• Authors : Cha R; Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Nakagawa S

Subjects: Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/genetics ; Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism

• Source: PloS one [PLoS One] 2025 Apr 01; Vol. 20 (4), pp. e0319976. Date of Electronic Publication: 2025 Apr 01 (Print Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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LRP receptors in chondrocytes are modulated by simulated microgravity and cyclic hydrostatic pressure

• Authors : Nordberg, Rachel C; Mellor, Liliana F; Krause, Andrew R

Subjects: Control Engineering; Mechatronics and Robotics; Engineering

• Source: PLOS ONE. 14(10)

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