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Academic Journal

Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

Authors : Ivin M; Max F. Perutz Laboratories, University of Vienna, Vienna Biocenter (VBC), Vienna, Austria.; Dumigan A

Subjects: Interferon Type I/Interferon Type I/Interferon Type I/*immunology ; Killer Cells, Natural/Killer Cells, Natural/Killer Cells, Natural/*immunology ; Klebsiella Infections/Klebsiella Infections/Klebsiella Infections/*immunology

Source: PLoS pathogens [PLoS Pathog] 2017 Nov 07; Vol. 13 (11), pp. e1006696. Date of Electronic Publication: 2017 Nov 07 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection

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Academic Journal

Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells.

Authors : Yiu WH; Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong.; Wong DW

Subjects: Diabetes Mellitus/Diabetes Mellitus/Diabetes Mellitus/*metabolism ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism ; Inflammation/Inflammation/Inflammation/*physiopathology

Source: PloS one [PLoS One] 2014 Feb 21; Vol. 9 (2), pp. e88894. Date of Electronic Publication: 2014 Feb 21 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.

Authors : Borad MJ; Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America ; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America

Subjects: Bile Duct Neoplasms/Bile Duct Neoplasms/Bile Duct Neoplasms/*drug therapy ; Cholangiocarcinoma/Cholangiocarcinoma/Cholangiocarcinoma/*drug therapy ; ErbB Receptors/ErbB Receptors/ErbB Receptors/*metabolism

Source: PLoS genetics [PLoS Genet] 2014 Feb 13; Vol. 10 (2), pp. e1004135. Date of Electronic Publication: 2014 Feb 13 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection

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Academic Journal

WSX-1 signalling inhibits CD4⁺ T cell migration to the liver during malaria infection by repressing chemokine-independent pathways.

Authors : Villegas-Mendez A; Department of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom ; Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

Subjects: Signal Transduction*; CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*metabolism ; Chemokine CCL4/Chemokine CCL4/Chemokine CCL4/*metabolism

Source: PloS one [PLoS One] 2013 Nov 07; Vol. 8 (11), pp. e78486. Date of Electronic Publication: 2013 Nov 07 (Print Publication: 2013).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Academic Journal

Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling.

Authors : Mohni KN; Department of Molecular, Microbial and Structural Biology and the Molecular Biology and Biochemistry Graduate Program, University of Connecticut Health Center, Farmington, Connecticut, United States of America.; Smith S

Subjects: Signal Transduction*; DNA Helicases/DNA Helicases/DNA Helicases/*metabolism ; DNA Primase/DNA Primase/DNA Primase/*metabolism

Source: PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (10), pp. e1003652. Date of Electronic Publication: 2013 Oct 03.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic

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Academic Journal

D1 dopamine receptor signaling is modulated by the R7 RGS protein EAT-16 and the R7 binding protein RSBP-1 in Caenoerhabditis elegans motor neurons.

Authors : Wani KA; Molecular and Cellular Biology Program, University of Massachusetts, Amherst, Massachusetts, United States of America.; Catanese M

Subjects: Caenorhabditis elegans Proteins/Caenorhabditis elegans Proteins/Caenorhabditis elegans Proteins/*metabolism ; GTP-Binding Protein Regulators/GTP-Binding Protein Regulators/GTP-Binding Protein Regulators/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

Source: PloS one [PLoS One] 2012; Vol. 7 (5), pp. e37831. Date of Electronic Publication: 2012 May 21.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic

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Academic Journal

Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch.

Authors : Patel KN; The Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.; Liu Q

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism ; Pruritus/Pruritus/Pruritus/*metabolism

Source: PloS one [PLoS One] 2011; Vol. 6 (5), pp. e20559. Date of Electronic Publication: 2011 May 31.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic

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Academic Journal

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.

Authors : Aste-Amézaga M; Department of Biologics Research, Merck Research Laboratories, West Point, Pennsylvania, United States of America.; Zhang N

Subjects: Mutation*; Antibodies, Monoclonal/Antibodies, Monoclonal/Antibodies, Monoclonal/*pharmacology ; Receptor, Notch1/Receptor, Notch1/Receptor, Notch1/*immunology

Source: PloS one [PLoS One] 2010 Feb 08; Vol. 5 (2), pp. e9094. Date of Electronic Publication: 2010 Feb 08.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic

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Academic Journal

PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling.

Authors : Bansal K; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.; Kapoor N

Subjects: Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/*metabolism ; Macrophages/Macrophages/Macrophages/*enzymology ; Matrix Metalloproteinase 9/Matrix Metalloproteinase 9/Matrix Metalloproteinase 9/*metabolism

Source: PloS one [PLoS One] 2009; Vol. 4 (3), pp. e4911. Date of Electronic Publication: 2009 Mar 17.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic

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Academic Journal

Activity-Dependent Bidirectional Regulation of GAD Expression in a Homeostatic Fashion Is Mediated by BDNF-Dependent and Independent Pathways.

Authors : Hanno-Iijima Y; Tokai University Institute of Innovative Science and Technology, Medical Division, Kanagawa, Japan; School of Medicine, Tokai University, Kanagawa, Japan.

Subjects: Gene Expression Regulation*/Gene Expression Regulation*/Gene Expression Regulation*/drug effects; Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/*physiology ; Glutamate Decarboxylase/Glutamate Decarboxylase/Glutamate Decarboxylase/*biosynthesis

Source: PloS one [PLoS One] 2015 Aug 04; Vol. 10 (8), pp. e0134296. Date of Electronic Publication: 2015 Aug 04 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection

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Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells.

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.

WSX-1 signalling inhibits CD4⁺ T cell migration to the liver during malaria infection by repressing chemokine-independent pathways.

Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling.

D1 dopamine receptor signaling is modulated by the R7 RGS protein EAT-16 and the R7 binding protein RSBP-1 in Caenoerhabditis elegans motor neurons.

Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch.

Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.

PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signaling.

Activity-Dependent Bidirectional Regulation of GAD Expression in a Homeostatic Fashion Is Mediated by BDNF-Dependent and Independent Pathways.