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Academic Journal

Tipping the balance toward transplantation tolerance: in vivo therapy using a mutated IL-2.

Authors : Camirand, Geoffrey¹; Lakkis, Fadi G.¹

Subjects: *SKIN grafting; *IMMUNOLOGICAL tolerance; *REGULATORY T cells

Source: Journal of Clinical Investigation. 3/1/2024, Vol. 134 Issue 5, p1-3. 3p.

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Academic Journal

Lessons learned: from mentored to mentor.

Authors : Heitman, Joseph¹

Subjects: *UNDERGRADUATES; *MEDICAL students; *POSTDOCTORAL programs

Source: Journal of Clinical Investigation. 1/17/2023, Vol. 133 Issue 2, p1-3. 4p.

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Academic Journal

Calcineurin inhibitors suppress acute graft-versus-host disease via NFAT-independent inhibition of T cell receptor signaling.

Authors : Otsuka, Shizuka¹; Melis, Nicolas²; Gaida, Matthias M.³

Subjects: *PERFORINS; *T cell receptors; *GRAFT versus host disease

Source: Journal of Clinical Investigation. 6/1/2021, Vol. 131 Issue 11, p1-15. 15p.

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Academic Journal

Phase I trial of donor-derived modified immune cell infusion in kidney transplantation.

Authors : Morath, Christian¹; Schmitt, Anita^2,3; Kleist, Christian^4,5

Subjects: *HOMOGRAFTS; *CLINICAL trials; *KIDNEY transplantation

Source: Journal of Clinical Investigation. May2020, Vol. 130 Issue 5, p2364-2376. 13p. 2 Diagrams, 3 Charts, 3 Graphs.

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Academic Journal

Emerging strategies for combination checkpoint modulators in cancer immunotherapy.

Authors : Popovic, Aleksandra¹; Jaffee, Elizabeth M.¹; Zaidi, Neeha¹

Subjects: *IMMUNOTHERAPY; *T cells; *ANTINEOPLASTIC agents

Source: Journal of Clinical Investigation. Aug2018, Vol. 128 Issue 8, p3209-3218. 10p.

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Academic Journal

Spleen mediates a distinct hematopoietic progenitor response supporting tumor-promoting myelopoiesis.

Authors : Chong Wu^1,2; Huiheng Ning²; Mingyu Liu²

Subjects: *SPLEEN; *HEMATOPOIETIC agents; *PROGENITOR cells

Source: Journal of Clinical Investigation. Aug2018, Vol. 128 Issue 8, p3425-3438. 14p.

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Academic Journal

Ibrutinib treatment improves T cell number and function in CLL patients.

Authors : Long, Meixiao^1,2; Beckwith, Kyle^1,2,3; Do, Priscilla^1,2,3

Subjects: *CHRONIC lymphocytic leukemia; *T cells; *PROTEIN-tyrosine kinases

Source: Journal of Clinical Investigation. Aug2017, Vol. 127 Issue 8, p3052-3064. 13p.

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Academic Journal

Exosomes and tumor-mediated immune suppression.

Authors : Whiteside, Theresa L.¹

Subjects: *EXOSOMES; *IMMUNOSUPPRESSIVE agents; *DNA analysis

Source: Journal of Clinical Investigation. Apr2016, Vol. 126 Issue 4, p1216-1223. 8p. 1 Black and White Photograph, 2 Diagrams.

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Academic Journal

Rabbit antithymocyte globulin-induced serum sickness disease and human kidney graft survival.

Authors : Couvrat-Desvergnes, Grégoire^1,2; Salama, Apolline^1,3,4; Le Berre, Ludmilla^1,2,3

Subjects: *SERUM sickness; *GLOBULINS; *T cells

Source: Journal of Clinical Investigation. 12/1/2015, Vol. 125 Issue 12, p4655-4665. 11p. 1 Diagram, 5 Charts, 3 Graphs.

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Academic Journal

Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity.

Authors : Berezhno, Alexey¹; Castro, Iris²; Levay, Agata¹

Subjects: *T cells; *IMMUNOSUPPRESSIVE agents; *MACROLIDE antibiotics

Source: Journal of Clinical Investigation. Jan2014, Vol. 124 Issue 1, p188-197. 10p. 6 Graphs.

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