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Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.

• Authors : Luth MR; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.; Godinez-Macias KP

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/pharmacology ; Antimalarials*/Antimalarials*/Antimalarials*/therapeutic use ; Drug Resistance*/Drug Resistance*/Drug Resistance*/genetics

• Source: Science (New York, N.Y.) [Science] 2024 Nov 29; Vol. 386 (6725), pp. eadk9893. Date of Electronic Publication: 2024 Nov 29.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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A single cell atlas of sexual development in Plasmodium falciparum .

• Authors : Dogga SK; Wellcome Sanger Institute, Hinxton CB10 1SA, UK.; Rop JC

Subjects: Erythrocytes*/Erythrocytes*/Erythrocytes*/parasitology ; Malaria, Falciparum*/Malaria, Falciparum*/Malaria, Falciparum*/parasitology ; Malaria, Falciparum*/Malaria, Falciparum*/Malaria, Falciparum*/transmission

• Source: Science (New York, N.Y.) [Science] 2024 May 03; Vol. 384 (6695), pp. eadj4088. Date of Electronic Publication: 2024 May 03.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Rethinking jaundice.

• Authors : Kloehn J; Department of Microbiology and Molecular Medicine, University of Geneva, Centre Médical Universitaire, Geneva, Switzerland.; Soldati-Favre D

Subjects: Bilirubin*/Bilirubin*/Bilirubin*/blood ; Bilirubin*/Bilirubin*/Bilirubin*/metabolism ; Jaundice*/Jaundice*/Jaundice*/blood

• Source: Science (New York, N.Y.) [Science] 2025 Jun 12; Vol. 388 (6752), pp. 1132-1133. Date of Electronic Publication: 2025 Jun 12.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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A metabolite-based resistance mechanism against malaria.

• Authors : Figueiredo A; Gulbenkian Institute for Molecular Medicine (GIMM), Avenida Professor Egas Moniz, Lisboa, Portugal.; Rastogi ST

Subjects: Bilirubin*/Bilirubin*/Bilirubin*/blood ; Bilirubin*/Bilirubin*/Bilirubin*/metabolism ; Glucuronosyltransferase*/Glucuronosyltransferase*/Glucuronosyltransferase*/genetics

• Source: Science (New York, N.Y.) [Science] 2025 Jun 12; Vol. 388 (6752), pp. eadq6741. Date of Electronic Publication: 2025 Jun 12.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Supersaturation mutagenesis reveals adaptive rewiring of essential genes among malaria parasites.

• Authors : Oberstaller J; Center for Global Health and Interdisciplinary Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA.; Xu S

Subjects: Genes, Essential* ; Plasmodium berghei*/Plasmodium berghei*/Plasmodium berghei*/genetics ; Plasmodium berghei*/Plasmodium berghei*/Plasmodium berghei*/metabolism

• Source: Science (New York, N.Y.) [Science] 2025 Feb 07; Vol. 387 (6734), pp. eadq7347. Date of Electronic Publication: 2025 Feb 07.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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An intrinsic oscillator drives the blood stage cycle of the malaria parasite Plasmodium falciparum.

• Authors : Smith, Lauren M.; Motta, Francis C.; Chopra, Garima

• Source: Science. 5/15/2020, Vol. 368 Issue 6492, p754-759. 6p. 5 Color Photographs.

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Major subpopulations of Plasmodium falciparum in sub-Saharan Africa.

• Authors : Amambua-Ngwa, Alfred¹; Amenga-Etego, Lucas²; Kamau, Edwin^3,4

• Source: Science. 8/23/2019, Vol. 365 Issue 6455, p813-816. 4p. 1 Color Photograph, 1 Diagram, 1 Graph, 1 Map.

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Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein.

• Authors : Dacon C; Antibody Biology Unit, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA.; Moskovitz R

Subjects: Protozoan Proteins*/Protozoan Proteins*/Protozoan Proteins*/immunology ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/immunology ; Sporozoites*/Sporozoites*/Sporozoites*/immunology

• Source: Science (New York, N.Y.) [Science] 2025 Jan 03; Vol. 387 (6729), pp. eadr0510. Date of Electronic Publication: 2025 Jan 03.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria.

• Authors : Chahine Z; Department of Molecular, Cell and Systems Biology, University of California, Riverside, CA, USA.; Abel S

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/chemistry ; Antimalarials*/Antimalarials*/Antimalarials*/pharmacology ; Apicoplasts*/Apicoplasts*/Apicoplasts*/drug effects

• Source: Science (New York, N.Y.) [Science] 2024 Sep 27; Vol. 385 (6716), pp. eadm7966. Date of Electronic Publication: 2024 Sep 27.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Artemisinin-resistant malaria in Africa demands urgent action.

• Authors : Dhorda M; Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/therapeutic use ; Artemisinins*/Artemisinins*/Artemisinins*/therapeutic use ; Artemisinins*/Artemisinins*/Artemisinins*/pharmacology

• Source: Science (New York, N.Y.) [Science] 2024 Jul 19; Vol. 385 (6706), pp. 252-254. Date of Electronic Publication: 2024 Jul 18.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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