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ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway.

• Authors : Huyghe J; VIB Center for Inflammation Research, 9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium.

Subjects: Apoptosis* ; Autophagy-Related Proteins*/Autophagy-Related Proteins*/Autophagy-Related Proteins*/genetics ; Autophagy-Related Proteins*/Autophagy-Related Proteins*/Autophagy-Related Proteins*/metabolism

• Source: Science (New York, N.Y.) [Science] 2022 Dec 16; Vol. 378 (6625), pp. 1201-1207. Date of Electronic Publication: 2022 Dec 15.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport.

• Authors : Roca FJ; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, Cambridge CB2 0AW, UK.; Whitworth LJ

Subjects: Electron Transport Complex I*/Electron Transport Complex I*/Electron Transport Complex I*/antagonists & inhibitors ; Electron Transport Complex I*/Electron Transport Complex I*/Electron Transport Complex I*/metabolism ; Macrophages*/Macrophages*/Macrophages*/metabolism

• Source: Science (New York, N.Y.) [Science] 2022 Jun 24; Vol. 376 (6600), pp. eabh2841. Date of Electronic Publication: 2022 Jun 24.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.

• Authors : Carballo E; Office of Clinical Research and Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.; Lai WS

Subjects: DNA-Binding Proteins* ; Immediate-Early Proteins* ; Zinc Fingers*

• Source: Science (New York, N.Y.) [Science] 1998 Aug 14; Vol. 281 (5379), pp. 1001-5.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.

• Authors : Hotamisligil GS; Dana-Farber Cancer Institute, Boston, MA.; Shargill NS

Subjects: Adipose Tissue/Adipose Tissue/Adipose Tissue/*physiopathology ; Insulin Resistance/Insulin Resistance/Insulin Resistance/*genetics ; Obesity/Obesity/Obesity/*genetics

• Source: Science (New York, N.Y.) [Science] 1993 Jan 01; Vol. 259 (5091), pp. 87-91.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Formation of ion-permeable channels by tumor necrosis factor-alpha.

• Authors : Kagan, B.L.; Baldwin, R.

• Source: Science. 3/13/1992, Vol. 255 Issue 5050, p1427. 4p. 3 Diagrams, 10 Graphs.

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Tumor necrosis factor-alpha activates the sphingomyelin signal transduction pathway in a cell-free system.

• Authors : Dressler KA; Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.; Mathias S

Subjects: Ceramides/Ceramides/Ceramides/*physiology ; Protein Kinases/Protein Kinases/Protein Kinases/*metabolism ; Receptors, Cell Surface/Receptors, Cell Surface/Receptors, Cell Surface/*physiology

• Source: Science (New York, N.Y.) [Science] 1992 Mar 27; Vol. 255 (5052), pp. 1715-8.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease.

• Authors : Pelczar P; I. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg, Germany.; Witkowski M

Subjects: CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*immunology ; Inflammatory Bowel Diseases/Inflammatory Bowel Diseases/Inflammatory Bowel Diseases/*immunology ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*immunology

• Source: Science (New York, N.Y.) [Science] 2016 Oct 21; Vol. 354 (6310), pp. 358-362.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.

• Authors : McIlwain DR; Campell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University Health Network (UHN), 620 University Avenue, Toronto, Ontario M5G 2C1, Canada.; Lang PA

Subjects: Immunity, Innate*; ADAM Proteins/ADAM Proteins/ADAM Proteins/*metabolism ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism

• Source: Science (New York, N.Y.) [Science] 2012 Jan 13; Vol. 335 (6065), pp. 229-32.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Information transduction capacity of noisy biochemical signaling networks.

• Authors : Cheong R; Department of Biomedical Engineering, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA.; Rhee A

Subjects: Signal Transduction*; Tumor Necrosis Factor-alpha/Tumor Necrosis Factor-alpha/Tumor Necrosis Factor-alpha/*metabolism; 3T3 Cells

• Source: Science (New York, N.Y.) [Science] 2011 Oct 21; Vol. 334 (6054), pp. 354-8. Date of Electronic Publication: 2011 Sep 15.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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Inactivation of TNF signaling by rationally designed dominant-negative TNF variants.

• Authors : Steed PM; Xencor, 111 West Lemon Avenue, Monrovia, CA 91016, USA.; Tansey MG

Subjects: Protein Engineering* ; Signal Transduction*; Tumor Necrosis Factor-alpha/Tumor Necrosis Factor-alpha/Tumor Necrosis Factor-alpha/*antagonists & inhibitors

• Source: Science (New York, N.Y.) [Science] 2003 Sep 26; Vol. 301 (5641), pp. 1895-8.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication

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