Search Results

miR-29c-3p downregulation accelerates spinal cord injury progression by targeting BRD4.

• Authors : Wang D; Department of Orthopedics, Zhangjiakou First Hospital, No. 6 Libaisi Lane, Qiaoxi District, Zhangjiakou City, Hebei Province, 075000, China. .; Wang X

Subjects: Spinal Cord Injuries*/Spinal Cord Injuries*/Spinal Cord Injuries*/genetics ; Spinal Cord Injuries*/Spinal Cord Injuries*/Spinal Cord Injuries*/blood ; Spinal Cord Injuries*/Spinal Cord Injuries*/Spinal Cord Injuries*/diagnosis

• Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2025 Jul 25; Vol. 20 (1), pp. 703. Date of Electronic Publication: 2025 Jul 25.Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium:

Record details

CCNY-mediated phosphorylation and TET2-BACH1-driven DNA demethylation activate PRC1 to augment NSCLC progression.

• Authors : Huang D; Department of Thoracic Surgery, Huashan Hospital of Fudan University, Shanghai, 200040, P.R. China.; Chu X

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2025 Jul 15; Vol. 44 (1), pp. 206. Date of Electronic Publication: 2025 Jul 15.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium:

Record details

BRD4 acts as a transcriptional repressor of RhoB to inhibit terminal erythropoiesis.

• Authors : Chen Y; Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, No.79 Qingchun Road, Hangzhou, 310058, China.; Institute of Hematology, Zhejiang University, Hangzhou, 310058, China.

Subjects: Erythropoiesis*/Erythropoiesis*/Erythropoiesis*/genetics ; Transcription Factors*/Transcription Factors*/Transcription Factors*/metabolism ; Transcription Factors*/Transcription Factors*/Transcription Factors*/antagonists & inhibitors

• Source: Journal of hematology & oncology [J Hematol Oncol] 2025 Jul 01; Vol. 18 (1), pp. 67. Date of Electronic Publication: 2025 Jul 01.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium:

Record details

Overexpression of oncogenic polo-like kinase 1 disrupts the invasiveness, cell cycle, and apoptosis in synovial sarcoma.

• Authors : Zhang J; Department of Pathology, Central People's Hospital of Zhanjiang & Zhanjiang Central Hospital, Guangdong Medical University, Zhanjiang, 524000, Guangdong, China.; Department of Pathology, The Third Hospital of Mianyang, Sichuan Mental Health Center, mianyang, 621000, Sichuan, China.

Subjects: Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/antagonists & inhibitors ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics

• Source: Journal of translational medicine [J Transl Med] 2025 Jun 20; Vol. 23 (1), pp. 691. Date of Electronic Publication: 2025 Jun 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium:

Record details

Cohesin stabilization at promoters and enhancers by common transcription factors and chromatin regulators.

• Authors : Bryan AF; Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.; Justice M

Subjects: Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/metabolism ; Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/Chromosomal Proteins, Non-Histone*/genetics ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism

• Source: Epigenetics & chromatin [Epigenetics Chromatin] 2025 Jun 09; Vol. 18 (1), pp. 33. Date of Electronic Publication: 2025 Jun 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101471619 Publication Model: Electronic Cited Medium:

Record details

Dynamic changes in vasohibin and nitric oxide signaling following surgical resection of head and neck squamous cell carcinoma.

• Authors : Tai YH; Department of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan.; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan.

Subjects: Squamous Cell Carcinoma of Head and Neck*/Squamous Cell Carcinoma of Head and Neck*/Squamous Cell Carcinoma of Head and Neck*/surgery ; Squamous Cell Carcinoma of Head and Neck*/Squamous Cell Carcinoma of Head and Neck*/Squamous Cell Carcinoma of Head and Neck*/pathology ; Squamous Cell Carcinoma of Head and Neck*/Squamous Cell Carcinoma of Head and Neck*/Squamous Cell Carcinoma of Head and Neck*/metabolism

• Source: World journal of surgical oncology [World J Surg Oncol] 2025 Jun 07; Vol. 23 (1), pp. 221. Date of Electronic Publication: 2025 Jun 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium:

Record details

The Src family kinase inhibitor drug Dasatinib and glucocorticoids display synergistic activity against tongue squamous cell carcinoma and reduce MET kinase activity.

• Authors : Hmedat, Ali N. A.^1,2 (AUTHOR); Doondeea, Jessica³ (AUTHOR); Ebner, Daniel⁴ (AUTHOR)

• Source: Cell Communication & Signaling. 6/19/2025, Vol. 23 Issue 1, p1-20. 20p.

Record details

Exploring the potential mechanisms of sorafenib resistance in hepatocellular carcinoma cell lines based on RNA sequencing.

• Authors : Sun, Minghui¹ (AUTHOR); Zhang, Zhi² (AUTHOR); Chen, Chunyan³ (AUTHOR)

• Source: Cancer Cell International. 3/13/2025, Vol. 25 Issue 1, p1-11. 11p.

Record details

Positive selection on rare variants of IGF1R and BRD4 underlying the cold adaptation of wild boar.

• Authors : Chen J; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, China.; Department of Ecology and Evolution, The University of Chicago, 1101E 57th Street, Chicago, IL, 60637, USA.

Subjects: Transcription Factors*/Transcription Factors*/Transcription Factors*/genetics ; Selection, Genetic* ; Sus scrofa*/Sus scrofa*/Sus scrofa*/genetics

• Source: Genetics, selection, evolution : GSE [Genet Sel Evol] 2025 Jul 16; Vol. 57 (1), pp. 40. Date of Electronic Publication: 2025 Jul 16.Publisher: BioMed Central Country of Publication: France NLM ID: 9114088 Publication Model: Electronic Cited Medium:

Record details

Comparative analysis of Microtus fortis and murine hosts reveals a correlation between BRD4 and hepatic inflammation during Schistosoma japonicum infection.

• Authors : Yuan M; Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, Guangdong, China.; Key Laboratory of Tropical Disease Control of the Ministry of Education, Sun Yat-sen University, Guangzhou, Guangdong, China.

Subjects: Schistosoma japonicum*/Schistosoma japonicum*/Schistosoma japonicum*/immunology ; Schistosoma japonicum*/Schistosoma japonicum*/Schistosoma japonicum*/physiology ; Transcription Factors*/Transcription Factors*/Transcription Factors*/genetics

• Source: Parasites & vectors [Parasit Vectors] 2025 Jul 04; Vol. 18 (1), pp. 259. Date of Electronic Publication: 2025 Jul 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium:

Record details