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Quantitative Structure-Activity Relationship Analysis of the Effect of Metoclopramide and Related Compounds on the Surface Ionization of Fumed Silica.

• Authors : Buyuktimkin, Tuba¹; Wurster, Dale Eric¹

Subjects: *Metoclopramide; *Silica fume; *Surface ionization

• Source: Journal of Pharmaceutical Sciences. Aug2015, Vol. 104 Issue 8, p2566-2573. 8p. 1 Diagram, 3 Charts, 4 Graphs.

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Three-Dimensional Quantitative Structure-Activity Relationship Analysis for Human Pregnane X Receptor for the Prediction of CYP3 A4 Induction in Human Hepatocytes: Structure-Based Comparative Molecular Field Analysis.

• Authors : Handa, Koichi^1,2; Nakagome, Izumi¹; Yamaotsu, Noriyuki¹

Subjects: *QSAR models; *Pregnane X receptor; *Liver cells

• Source: Journal of Pharmaceutical Sciences. Jan2015, Vol. 104 Issue 1, p223-232. 10p.

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Investigation of DNA-binding properties of organic molecules using quantitative structure-activity relationship (QSAR) models.

• Authors : Verma, Rajeshwar P.¹ ; Hansch, Corwin¹

Subjects: *DNA; *QSAR models; *Drug design

• Source: Journal of Pharmaceutical Sciences. Jan2008, Vol. 97 Issue 1, p88-110. 23p. 2 Diagrams, 10 Charts, 1 Graph.

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Uncertainty management for In Silico screening of reversed-phase liquid chromatography methods for small compounds.

• Authors : Van Laethem, Thomas; Kumari, Priyanka; Boulanger, Bruno ...

Subjects: Method development; Multi-criteria decision analysis; Response surface methodology

• Source: Journal of Pharmaceutical and Biomedical Analysis, 249, 116373 (2024-10-15)

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Direct In Vivo Human Intestinal Permeability ( Peff) Determined with Different Clinical Perfusion and Intubation Methods.

• Authors : Dahlgren, David¹; Roos, Carl¹; Sjögren, Erik¹

Subjects: *Drug development; *Drug absorption; *Intestinal absorption

• Source: Journal of Pharmaceutical Sciences. Sep2015, Vol. 104 Issue 9, p2702-2726. 25p. 4 Color Photographs, 14 Charts, 7 Graphs.

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Prediction of concentration-time profile and its inter-individual variability following the dermal drug absorption.

• Authors : Polak, Sebastian^1,2; Ghobadi, Cyrus¹; Mishra, Himanshu¹

Subjects: *Prediction models; *Transdermal medication; *Drug absorption

• Source: Journal of Pharmaceutical Sciences. Jul2012, Vol. 101 Issue 7, p2584-2595. 12p. 2 Diagrams, 3 Charts, 5 Graphs.

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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration-time profiles in human from in vivo preclinical data by using the Wajima approach.

• Authors : Vuppugalla, Ragini¹; Marathe, Punit¹; He, Handan²

Subjects: *Prediction models; *Pharmacokinetics; *Allometry

• Source: Journal of Pharmaceutical Sciences. Oct2011, Vol. 100 Issue 10, p4111-4126. 16p.

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Robust QSAR model development in high-throughput catalyst discovery based on genetic parameter optimisation.

• Authors : Wang, Xue Z.¹ ; Perston, Ben¹; Yang Yang¹

• Source: Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers Part A. Oct2009, Vol. 87 Issue 10, p1420-1429. 10p.

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Structure-activity correlations for psychotomimetics

• Authors : Clare, B.W.

Subjects: Journal Article

• Source: Clare, B.W.

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