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Comprehensive transcriptome-wide analysis of spliceopathy correction of myotonic dystrophy using CRISPR-Cas9 in iPSCs-derived cardiomyocytes

Authors : Kshitiz Singh; Denis Furling; Sumitava Dastidar ...

Subjects: Candidate gene; TNNT2; Research & Experimental Medicine

Source: Molecular TherapyMolecular Therapy, Cell Press, 2021, 29 (11), ⟨10.1016/j.ymthe.2021.08.004⟩

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Evolutionary Dynamics of the Spindle Assembly Checkpoint in Eukaryotes

Authors : Kops, Geert J.P.L.; Snel, Berend; Tromer, Eelco C. ...

Subjects: 0301 basic medicine; Biology; Biochemistry

Source: Current Biology, 30(10), R589. Cell Press

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First conditional marketing authorization approval in the European Union for hemophilia 'A' gene therapy

Authors : Thierry VandenDriessche; Steven W. Pipe; Glenn F. Pierce ...

Subjects: Medicine(all); Marketing; Pharmacology

Source: Molecular Therapy. 30:3335-3336

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Microtubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congression

Authors : Wu, Jingchao; Larreategui-Aparicio, Ainhoa; Lambers, Maaike L A ...

Subjects: cell division; mitosis; pericentrin

Source: Current Biology. 33:912-925.e6

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A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion

Authors : Makoto Nishiyama; Marc Tessier-Lavigne; Elke Stein

Subjects: Receptor complex; animal structures; Deleted in Colorectal Cancer

Source: Cell. 186:230

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Analysis of RNA polymerase II ubiquitylation and proteasomal degradation

Authors : Anindya Roy; Jesper Q. Svejstrup; Vesela Encheva

Subjects: Proteasome Endopeptidase Complex; Transcription, Genetic; Ubiquitylation

Source: Tufegdzic Vidakovic, A, Harreman, M, Dirac-Svejstrup, A B, Boeing, S, Roy, A, Encheva, V, Neumann, M, Wilson, M, Snijders, A P & Svejstrup, J Q 2019, ' Analysis of RNA polymerase II ubiquitylation and

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Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century

Authors : Shamam Waldman; Daniel Backenroth; Éadaoin Harney

Subjects: runs of homozygosity; Biochemistry, Genetics and Molecular Biology(all); founder event

Source: Cell, 185(25), P4703. Cell Press

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A Highly Potent Antibody Effective Against SARS-CoV-2 Variants of Concern

Authors : Giuseppe Pantaleo; Pieter Leyssen; Kelvin Lau ...

Subjects: General Biochemistry, Genetics and Molecular Biology; SARS-CoV-2; neutralizing antibodies

Source: Cell ReportsFenwick, Craig; Turelli, Priscilla; Perez, Laurent; Pellaton, Céline; Esteves-Leuenberger, Line; Farina, Alex; Campos, Jérémy; Lana, Erica; Fiscalini, Flurin; Raclot, Charlène;

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On the probabilistic nature of the species-area relation

Authors : Jonathan Giezendanner; Andrea Giometto; Andrea Rinaldo ...

Subjects: 0301 basic medicine; Immunology and Microbiology (all); Insular biogeography

Source: Journal of Theoretical Biology. 462:391-407

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Isolation, cultivation, and application of primary respiratory epithelial cells obtained by nasal brushing, polyp samples, or lung explants

Authors : Anita Golec; Iwona Pranke; Paolo Scudieri ...

Subjects: Cystic Fibrosis; Neuroscience(all); Nasal epithelium

Source: Golec, A, Pranke, I, Scuderi, P, Hayes, K, Dreano, E, Dunlevy, F, Hatton, A, Downey, D G, Galietta, L & Sermet, I 2022, ' Isolation, cultivation, and application of primary respiratory epithelial

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