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ATP-based cell viability assay is superior to trypan blue exclusion and XTT assay in measuring cytotoxicity of anticancer drugs Taxol and Imatinib, and proteasome inhibitor MG-132 on human hepatoma cell line HepG2.

• Authors : Nowak, Elisabeth¹; Kammerer, Sarah¹ ; Küpper, Jan-Heiner¹

• Source: Clinical Hemorheology & Microcirculation. 2018, Vol. 69 Issue 1-2, p327-336. 10p.

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In vitro simulation of the liver first-pass effect with biotransformation-competent HepG2 cells to study effects of MG-132 on liver and cancer cells.

• Authors : Kammerer, Sarah¹ (AUTHOR) ; Nowak, Elisabeth^1,2 (AUTHOR); Mantke, René³ (AUTHOR)

• Source: Clinical Hemorheology & Microcirculation. 2024, Vol. 86 Issue 1/2, p159-168. 10p.

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The Proteasome as a Novel Target for the Treatment of Breast Cancer1

• Authors : Julian Adams

Subjects: Cancer Research; Bortezomib; business.industry

• Source: Breast Disease. 15:61-70

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A free radical-generating system regulates aβpp metabolism/processing: Involvement of the ubiquitin/proteasome and autophagy/lysosome pathways

• Authors : Isabel Sastre; Victor A. Munive; Fernando Valdivieso

Subjects: Proteasome Endopeptidase Complex; Free Radicals; Biology

• Source: Digital.CSIC. Repositorio Institucional del CSICinstname

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Local induction of heat shock protein 70 (Hsp70) by proteasome inhibition confers chondroprotection during surgically induced osteoarthritis in the rat knee.

• Authors : Etienne, Stéphanie¹; Gaborit, Nadège¹; Henrionnet, Christel¹

• Source: Bio-Medical Materials & Engineering. 2008, Vol. 18 Issue 4/5, p253-260. 8p. 2 Graphs.

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Alzheimer Research Forum Live Discussion: Alzheimer's: A triple whammy. Why are so many neurodegenerative diseases single, double, or triple amyloidoses?

• Source: Journal of Alzheimer's Disease. 2005, Vol. 7 Issue 1, p85-91. 7p.

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The Proteasome as a Novel Target for the Treatment of Breast Cancer.

• Authors : Adams, Julian

Subjects: PROTEOLYTIC enzymes; BREAST cancer treatment; BREAST diseases

• Source: Breast Disease; 2002, Vol. 15 Issue 1, p61, 10p

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Bortezomib could down-regulate the expression of RANKL, inhibit cell proliferation and induce cell apoptosis in the human myeloma cell line RPMI 8226 by activating casepase-3.

• Authors : Li Lin¹; Dong Chen¹; Zhen-Fei Xiang²

• Source: Cancer Biomarkers. 2017, Vol. 20 Issue 2, p217-224. 8p.

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HDL-mediated reduction of cholesterol content inhibits the proliferation of prostate cancer cells induced by LDL: Role of ABCA1 and proteasome inhibition.

• Authors : Ossoli A; Centro Enrica Grossi Paoletti, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, Milan, Italy.; Giorgio E

Subjects: Cholesterol*/Cholesterol*/Cholesterol*/metabolism ; Lipoproteins, HDL*/Lipoproteins, HDL*/Lipoproteins, HDL*/metabolism ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/drug therapy

• Source: BioFactors (Oxford, England) [Biofactors] 2022 May; Vol. 48 (3), pp. 707-717. Date of Electronic Publication: 2022 May 17.Publisher: Ios Press Country of Publication: Netherlands NLM ID: 8807441 Publication Model: Print-Electronic Cited Medium:

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Inhibition of glycoprotein synthesis in the endoplasmic reticulum as a novel anticancer mechanism of (-)-epigallocatechin-3-gallate.

• Authors : Konta L; Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University & MTA-SE Pathobiochemistry Research Group, Budapest, Hungary.; Száraz P

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Catechin/Catechin/Catechin/*analogs & derivatives ; Endoplasmic Reticulum/Endoplasmic Reticulum/Endoplasmic Reticulum/*metabolism

• Source: BioFactors (Oxford, England) [Biofactors] 2011 Nov-Dec; Vol. 37 (6), pp. 468-76. Date of Electronic Publication: 2011 Dec 08.Publisher: Ios Press Country of Publication: Netherlands NLM ID: 8807441 Publication Model: Print-Electronic Cited Medium:

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