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FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions

• Authors : Pablo Alcón; Artur P. Kaczmarczyk; Korak Kumar Ray ...

Subjects: Cell Extracts; DNA Replication; Models, Molecular

• Source: Nature

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Validation of the BOADICEA model for epithelial tubo-ovarian cancer risk prediction in UK Biobank

• Authors : Xin Yang; Yujia Wu; Lorenzo Ficorella ...

Subjects: BRCA2 Protein; Ovarian Neoplasms; Adult

• Source: Br J Cancer

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FANCA promotes lung adenocarcinoma progression and is a potential target for epitope vaccine immunotherapy

• Authors : Yanli Kang; Ruifang Zhong; Yuhan Gan

Subjects: Male; Lung Neoplasms; Fanconi Anemia Complementation Group A Protein

• Source: J Transl MedJournal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)

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FANCD2 genome binding is nonrandom and is enriched at large transcriptionally active neural genes prone to copy number variation

• Authors : Blaize, Justin L.; Garzon, Jada Lauren N.; Howlett, Niall G.

Subjects: Neurons; DNA Replication; Fanconi Anemia

• Source: Funct Integr Genomics

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Spectrum and characteristics of germline PALB2 pathogenic variants in 1556 early-onset breast cancer patients in China

• Authors : Li, Jing; He, Peng; Cai, Qindong

Subjects: Adult; BRCA2 Protein; 0301 basic medicine

• Source: J Cancer Res Clin Oncol

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Fanconi anemia DNA crosslink repair factors protect against LINE-1 retrotransposition during mouse development

• Authors : Nazareno Bona; Gerry P. Crossan; Apollo - University of Cambridge Repository

Subjects: DNA-Binding Proteins; Mice; Fanconi Anemia

• Source: Nat Struct Mol Biol

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FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations

• Authors : Patrycja Pawlikowska; Laure Delestré; Sebastian Gregoricchio

Subjects: Mice; Heterozygote; Leukemia

• Source: Oncogene

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The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks

• Authors : van de Kooij, Bert; van der Wal, Fenna J; Rother, Magdalena B ...

Subjects: Endodeoxyribonucleases; DNA End-Joining Repair; DNA Repair

• Source: Nat CommunbioRxivNature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

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FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.

• Authors : Alcón, Pablo; Kaczmarczyk, Artur P; Ray, Korak Kumar

Subjects: Animals; Female; Humans

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The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

• Authors : Tamara Sijacki; Pablo Alcón; Zhuo A. Chen

Subjects: 0303 health sciences; 03 medical and health sciences; Fanconi Anemia

• Source: Sijacki, T, Alcón, P, Chen, Z A, Mclaughlin, S H, Shakeel, S, Rappsilber, J & Passmore, L A 2022, ' The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination ',

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