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Academic Journal

Trichosanthin Promotes Anti-Tumor Immunity through Mediating Chemokines and Granzyme B Secretion in Hepatocellular Carcinoma.

Authors : Wang K; School of Dentistry, Shenzhen University Medical School, Shenzhen 518000, China.; Department of Biology, Faculty of Science, Hong Kong Baptist University, Hongkong 999077, China.

Subjects: Trichosanthin*/Trichosanthin*/Trichosanthin*/pharmacology ; Trichosanthin*/Trichosanthin*/Trichosanthin*/therapeutic use ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/drug therapy

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 11; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Sixty-Year Research and Development of Trichosanthin, a Ribosome-Inactivating Protein.

Authors : Lu JQ; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China.; Wong KB

Subjects: Trichosanthin*/Trichosanthin*/Trichosanthin*/chemistry ; Trichosanthin*/Trichosanthin*/Trichosanthin*/pharmacology; Animals

Source: Toxins [Toxins (Basel)] 2022 Feb 27; Vol. 14 (3). Date of Electronic Publication: 2022 Feb 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651

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Academic Journal

Comparative Proteomic Analysis of Drug Trichosanthin Addition to BeWo Cell Line.

Authors : Hu Y; Shanghai Stomatological Hospital & School of Stomatology, Fudan University, 356 Beijing East Road, Shanghai 200001, China.; Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Trichosanthin*/Trichosanthin*/Trichosanthin*/pharmacology; Cell Line

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Feb 28; Vol. 27 (5). Date of Electronic Publication: 2022 Feb 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Constructing a better binding peptide for drug delivery targeting the interleukin-4 receptor.

Authors : Bai XD; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.; Cao XW

Subjects: Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*pharmacology ; Peptides/Peptides/Peptides/*administration & dosage ; Protein Binding/Protein Binding/Protein Binding/*physiology

Source: Journal of drug targeting [J Drug Target] 2020 Nov; Vol. 28 (9), pp. 970-981. Date of Electronic Publication: 2020 May 18.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9312476 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Trichosanthin cooperates with Granzyme B to restrain tumor formation in tongue squamous cell carcinoma.

Authors : Zhu Z; School of Dentistry, Shenzhen University Health Science Center, Shenzhen, China.; School of Basic Medical Sciences, Shenzhen University Health Science Center, Shenzhen, China.

Subjects: Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/Carcinoma, Squamous Cell/*drug therapy ; Granzymes/Granzymes/Granzymes/*therapeutic use ; Tongue Neoplasms/Tongue Neoplasms/Tongue Neoplasms/*drug therapy

Source: BMC complementary medicine and therapies [BMC Complement Med Ther] 2021 Mar 09; Vol. 21 (1), pp. 88. Date of Electronic Publication: 2021 Mar 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101761232 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-7671

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Academic Journal

Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein.

Authors : Shi WW; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Sha Tin New Town, Hong Kong, China. .; Wong KB

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use

Source: Toxins [Toxins (Basel)] 2018 Aug 20; Vol. 10 (8). Date of Electronic Publication: 2018 Aug 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651

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Academic Journal

A novel trichosanthin fusion protein with increased cytotoxicity to tumor cells.

Authors : Lin B; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.; Yang XZ

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*metabolism ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Heparin-binding EGF-like Growth Factor/Heparin-binding EGF-like Growth Factor/Heparin-binding EGF-like Growth Factor/*chemistry

Source: Biotechnology letters [Biotechnol Lett] 2017 Jan; Vol. 39 (1), pp. 71-78. Date of Electronic Publication: 2016 Oct 06.Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8008051 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A novel extraction of trichosanthin from Trichosanthes kirilowii roots using three-phase partitioning and its in vitro anticancer activity.

Authors : Mondal A; Drug Development Diagnostics & Biotechnology Division, Indian Institute of Chemical Biology , Kolkata , India.

Subjects: Plant Roots* ; Trichosanthes*; Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*isolation & purification

Source: Pharmaceutical biology [Pharm Biol] 2014 Jun; Vol. 52 (6), pp. 677-80. Date of Electronic Publication: 2014 Feb 07.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanism of the specific neuronal toxicity of a type I ribosome-inactivating protein, trichosanthin.

Authors : Sha O; Faculty of Medicine, School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin NT, Hong Kong, China. ; Yew DT

Subjects: Neurons/Neurons/Neurons/*drug effects ; Retina/Retina/Retina/*drug effects ; Ribosome Inactivating Proteins, Type 1/Ribosome Inactivating Proteins, Type 1/Ribosome Inactivating Proteins, Type 1/*toxicity

Source: Neurotoxicity research [Neurotox Res] 2010 Aug; Vol. 18 (2), pp. 161-72. Date of Electronic Publication: 2009 Oct 23.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses.

Authors : Chan DS; Department of Biochemistry, Centre for Protein Science and Crystallography and Molecular Biotechnology Programme, The Chinese University of Hong Kong, Shatin, Hong Kong, China.; Chu LO

Subjects: Phosphoproteins/Phosphoproteins/Phosphoproteins/*chemistry ; Ribosomal Proteins/Ribosomal Proteins/Ribosomal Proteins/*chemistry ; Trichosanthin/Trichosanthin/Trichosanthin/*chemistry

Source: Nucleic acids research [Nucleic Acids Res] 2007; Vol. 35 (5), pp. 1660-72. Date of Electronic Publication: 2007 Feb 18.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Trichosanthin Promotes Anti-Tumor Immunity through Mediating Chemokines and Granzyme B Secretion in Hepatocellular Carcinoma.

A Sixty-Year Research and Development of Trichosanthin, a Ribosome-Inactivating Protein.

Comparative Proteomic Analysis of Drug Trichosanthin Addition to BeWo Cell Line.

Constructing a better binding peptide for drug delivery targeting the interleukin-4 receptor.

Trichosanthin cooperates with Granzyme B to restrain tumor formation in tongue squamous cell carcinoma.

Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein.

A novel trichosanthin fusion protein with increased cytotoxicity to tumor cells.

A novel extraction of trichosanthin from Trichosanthes kirilowii roots using three-phase partitioning and its in vitro anticancer activity.

Mechanism of the specific neuronal toxicity of a type I ribosome-inactivating protein, trichosanthin.

Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses.