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Academic Journal

Age, sex and Alzheimer's disease: a longitudinal study of 3xTg-AD mice reveals sex-specific disease trajectories and inflammatory responses mirrored in postmortem brains from Alzheimer's patients.

  • Authors : Barber AJ; Department of Neurology, Geisel School of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Del Genio CL

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Jun 22; Vol. 16 (1), pp. 134. Date of Electronic Publication: 2024 Jun 22.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Brain age as a biomarker for pathological versus healthy ageing - a REMEMBER study.

  • Authors : Wittens MMJ; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.; Department of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium.

Subjects: Brain*/Brain*/Brain*/diagnostic imaging ; Brain*/Brain*/Brain*/pathology ; Cognitive Dysfunction*/Cognitive Dysfunction*/Cognitive Dysfunction*/diagnostic imaging

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Jun 14; Vol. 16 (1), pp. 128. Date of Electronic Publication: 2024 Jun 14.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tau propagation in the brain olfactory circuits is associated with smell perception changes in aging.

  • Authors : Diez I; Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

Subjects: tau Proteins*/tau Proteins*/tau Proteins*/metabolism ; tau Proteins*/tau Proteins*/tau Proteins*/genetics ; Olfactory Perception*/Olfactory Perception*/Olfactory Perception*/physiology

  • Source: Nature communications [Nat Commun] 2024 Jun 06; Vol. 15 (1), pp. 4809. Date of Electronic Publication: 2024 Jun 06.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Associations between regional blood-brain barrier permeability, aging, and Alzheimer's disease biomarkers in cognitively normal older adults.

  • Authors : Denkinger M; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California, United States of America.; Baker S

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnostic imaging ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/metabolism

  • Source: PloS one [PLoS One] 2024 Jun 05; Vol. 19 (6), pp. e0299764. Date of Electronic Publication: 2024 Jun 05 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

RCAN1 knockout and overexpression recapitulate an ensemble of rest-activity and circadian disruptions characteristic of Down syndrome, Alzheimer's disease, and normative aging.

  • Authors : Wong H; Institute for Behavioral Genetics, University of Colorado Boulder, 1480 30th Street, Boulder, CO, 80309-0447, USA.; Department of Integrative Physiology, University of Colorado, Boulder, CO, 80303, USA.

Subjects: Aging*/Aging*/Aging*/physiology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism

  • Source: Journal of neurodevelopmental disorders [J Neurodev Disord] 2022 May 24; Vol. 14 (1), pp. 33. Date of Electronic Publication: 2022 May 24.Publisher: BioMed Central Country of Publication: England NLM ID: 101483832 Publication Model: Electronic Cited Medium: Internet ISSN: 1866-1955

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Academic Journal

Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease.

Subjects: Aging/Aging/Aging/*pathology ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*physiopathology ; Brain/Brain/Brain/*physiopathology

  • Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Feb 16; Vol. 42 (7), pp. 1362-1373. Date of Electronic Publication: 2022 Jan Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome.

  • Authors : Wegiel J; Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY, 10314, USA. .; Flory M

Subjects: Aging/Aging/Aging/*pathology ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology ; Brain/Brain/Brain/*pathology

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2022 Jan 04; Vol. 10 (1), pp. 2. Date of Electronic Publication: 2022 Jan 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Sex differences in the neuropathological hallmarks of Alzheimer's disease: focus on cognitively intact elderly individuals.

  • Authors : Hu YT; Department of Neurobiology and Department of Neurology of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P.R. China.; NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Research and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, Hangzhou, Zhejiang, P.R. China.

Subjects: Aging/Aging/Aging/*physiology ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism

  • Source: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2021 Dec; Vol. 47 (7), pp. 958-966. Date of Electronic Publication: 2021 May 27.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 7609829 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease.

  • Authors : Ferrer I; Department of Pathology and Experimental Therapeutics, University of Barcelona, Hospitalet de Llobregat, Spain.; CIBERNED (Network Centre of Biomedical Research of Neurodegenerative Diseases), Institute of Health Carlos III, Hospitalet de Llobregat, Spain.

Subjects: Aging/Aging/Aging/*metabolism ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Brain/Brain/Brain/*metabolism

  • Source: Brain pathology (Zurich, Switzerland) [Brain Pathol] 2021 Nov; Vol. 31 (6), pp. e12996. Date of Electronic Publication: 2021 Jul 04.Publisher: International Society of Neuropathology Country of Publication: Switzerland NLM ID: 9216781 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Estrogenic hormones receptors in Alzheimer's disease.

  • Authors : Tecalco-Cruz AC; Programa en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México (UACM), Apdo. Postal 03100, Ciudad de México, México. .; Zepeda-Cervantes J

Subjects: Aging/Aging/Aging/*metabolism ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*metabolism ; Estrogen Receptor alpha/Estrogen Receptor alpha/Estrogen Receptor alpha/*metabolism

  • Source: Molecular biology reports [Mol Biol Rep] 2021 Nov; Vol. 48 (11), pp. 7517-7526. Date of Electronic Publication: 2021 Oct 16.Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4978

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