Authors : D'Acunzo P; Center for Dementia Research, Nathan S. Kline Institute for Psychiatric Research, 10962, Orangeburg, NY, USA.; Department of Psychiatry, New York University Grossman School of Medicine, 10016, New York, NY, USA.

Subjects: Down Syndrome* ; Alzheimer Disease* ; Mitochondrial Diseases*

Source: Molecular neurodegeneration [Mol Neurodegener] 2024 Apr 14; Vol. 19 (1), pp. 34. Date of Electronic Publication: 2024 Apr 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

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Beyond Quiescent and Active: Intermediate Microglial Transcriptomic States in a Mouse Model of Down Syndrome.

Authors : Fernández-Blanco Á; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, 08003 Barcelona, Spain.; Sierra C

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism; Animals

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 14; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Voxel-based dysconnectomic brain morphometry with computed tomography in Down syndrome.

Authors : Sánchez-Moreno B; Adult Down Syndrome Unit, Department of Internal Medicine, Hospital Universitario de La Princesa, Madrid, Spain.; Zhang L

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/diagnostic imaging ; Down Syndrome*/Down Syndrome*/Down Syndrome*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/diagnostic imaging

Source: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2024 Jan; Vol. 11 (1), pp. 143-155. Date of Electronic Publication: 2023 Dec 29.Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model:

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Distinct Molecular Signatures of Amyloid-Beta and Tau in Alzheimer's Disease Associated with Down Syndrome.

Authors : Ichimata S; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, ON M5T 2S8, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 18; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B.

Authors : Wu Y; The UK Dementia Research Institute, University College London, Queen Square, London, WC1N 3BG, UK.; Mumford P

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology; Humans

Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Aug 14; Vol. 11 (1), pp. 132. Date of Electronic Publication: 2023 Aug 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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The Global Deterioration Scale for Down Syndrome Population (GDS-DS): A Rating Scale to Assess the Progression of Alzheimer's Disease.

Authors : Rodríguez-Hidalgo E; Specialized Service in Mental Health and Intellectual Disability, Institute of Health Assistance (IAS), Parc Hospitalari Martí i Julià, 17190 Girona, Spain.; Neurodevelopmental Group [Girona Biomedical Research Institute]-IDIBGI, Institute of Health Assistance (IAS), Parc Hospitalari Martí i Julià, 17190 Girona, Spain.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/epidemiology ; Down Syndrome*/Down Syndrome*/Down Syndrome*/epidemiology; Adult

Source: International journal of environmental research and public health [Int J Environ Res Public Health] 2023 Mar 14; Vol. 20 (6). Date of Electronic Publication: 2023 Mar 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601

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Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome.

Authors : Campbell NB; Department of Anatomy & Neurobiology, Boston University Chobanian & Avedesian School of Medicine, Boston University, Boston, MA 02118, USA.; Patel Y

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 09; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Amyloid precursor protein 𝛽CTF accumulates in synapses in sporadic and genetic forms of Alzheimer's disease.

Authors : Ferrer-Raventós P; Department of Neurology, Sant Pau Memory Unit, Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Down Syndrome*/Down Syndrome*/Down Syndrome*/metabolism; Humans

Source: Neuropathology and applied neurobiology [Neuropathol Appl Neurobiol] 2023 Feb; Vol. 49 (1), pp. e12879.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 7609829 Publication Model: Print Cited Medium: Internet ISSN:

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Reporting Down syndrome on the death certificate for Alzheimer disease/unspecified dementia deaths.

Authors : Landes SD; Department of Sociology and Aging Studies Institute, Maxwell School of Citizenship and Public Affairs, Syracuse University, Syracuse, NY, United States of America.; Finan JM

Subjects: Alzheimer Disease* ; Down Syndrome*/Down Syndrome*/Down Syndrome*/complications; Adult

Source: PloS one [PLoS One] 2023 Feb 13; Vol. 18 (2), pp. e0281763. Date of Electronic Publication: 2023 Feb 13 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Research attitudes in families of individuals with Down syndrome: importance for clinical trials.

Authors : Lott IT; Department of Pediatrics, University of California, Irvine, Orange, CA, 92868, USA. .; Kirby KA

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/therapy; Humans

Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2022 Nov 23; Vol. 14 (1), pp. 176. Date of Electronic Publication: 2022 Nov 23.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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