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Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 to Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution

Subjects: STAT3 Transcription Factor; 0301 basic medicine; medicine.medical_treatment

  • Source: Pharmacol RevPharmacological Reviews

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Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases

Subjects: 0301 basic medicine; STAT3 Transcription Factor; parthenolide

  • Source: Molecules : A Journal of Synthetic Chemistry and Natural Product ChemistryMolecules, Vol 23, Iss 6, p 1478 (2018)MoleculesVolume 23Issue 6

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Novel Therapeutic Approaches in Rheumatoid Arthritis: Role of Janus Kinases Inhibitors

Subjects: 0301 basic medicine; Rheumatoid Arthritis; Inflammation

  • Source: Current Medicinal Chemistry. 26:2823-2843

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Role of Janus-Kinases in Major Depressive Disorder

Subjects: 0301 basic medicine; medicine.medical_specialty; Medizin

  • Source: Neurosignals, Vol 24, Iss 1, Pp 71-80 (2016)

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Janus kinases and Src family kinases in the regulation of EGF-induced vimentin expression in MDA-MB-468 breast cancer cells

Subjects: 0301 basic medicine; Epithelial-Mesenchymal Transition; Vimentin

  • Source: The international journal of biochemistrycell biology. 76

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Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases

Subjects: STAT3 Transcription Factor; 0301 basic medicine; Amino Acid Motifs

  • Source: Molecular Biology of the Cell

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Driver mutations in Janus kinases in a mouse model of B-cell leukemia induced by deletion of PU.1 and Spi-B

Subjects: 0301 basic medicine; Mutagenesis (molecular biology technique); Biology

  • Source: Paediatrics Publications

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Targeted inhibition of Janus kinases abates interfon gamma-induced invasive behaviour of fibroblast-like synoviocytes

Subjects: 0301 basic medicine; Adult; Male

  • Source: Rheumatology (Oxford, England). 57(3)

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JAK inhibitors: Ten years after

Subjects: 0301 basic medicine; autoimmunity; covid-19

  • Source: European Journal of Immunology. 51:1615-1627

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A novel JAK/ROCK inhibitor, CPL409116, demonstrates potent efficacy in the mouse model of systemic lupus erythematosus

Subjects: 0301 basic medicine; Lupus; Mice, Transgenic

  • Source: Journal of Pharmacological Sciences, Vol 145, Iss 4, Pp 340-348 (2021)

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  • 1-10 of  709 results for ""Janus Kinases""