Search Results

The Role of Autophagy in Excitotoxicity, Synaptic Mitochondrial Stress and Neurodegeneration

• Authors : Charleen T. Chu

Subjects: post-synaptic calcium; Alzheimer disease; Epilepsy

• Source: Autophagy Reports, Vol 4, Iss 1 (2025)

Record details

Development of potent humanized TNFα inhibitory nanobodies for therapeutic applications in TNFα-mediated diseases

• Authors : Tao Yin; Aubin Ramon; Matthew Greenig

Subjects: Alzheimer disease; nanobody; single-domain antibody

• Source: mAbs, Vol 17, Iss 1 (2025)

Record details

The role of ferroptosis in Alzheimer's disease: Mechanisms and therapeutic potential (Review).

• Authors : Zeng H; Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.; Jin Z

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/drug effects ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy

• Source: Molecular medicine reports [Mol Med Rep] 2025 Jul; Vol. 32 (1). Date of Electronic Publication: 2025 May 09.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

• Source: Global Study to Investigate Safety and Efficacy of Donanemab in Early Symptomatic Alzheimer's Disease

Record details

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

• Authors : Vanderbilt Kennedy Center; Alexander Christian Conley, PhD, Principal Investigator

• Source: Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Record details

Cognitive Stimulation in Older Adults With Alzheimer's Disease

• Source: Cognitive Stimulation in Older Adults With Alzheimer's Disease: Effects Across Multiple Domains and in Institutional and Sociogeographic Contexts

Record details

Distinct composition of different types of Abeta plaques in the pathogenesis of Alzheimer's disease and the role of neutrophil-derived myeloperoxidase.

• Authors : Sun J; Department of Human Anatomy, Histology and Embryology, National Human Brain Bank for Development and Function, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, No. 5 Dongdansantiao, Dongcheng District, Beijing, 100005, P. R. China.; Shao X

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/enzymology ; Peroxidase*/Peroxidase*/Peroxidase*/metabolism

• Source: Molecular brain [Mol Brain] 2025 Jun 22; Vol. 18 (1), pp. 53. Date of Electronic Publication: 2025 Jun 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

Record details

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis.

• Authors : Ziff OJ; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, University College London, London, UK.; Parfitt GM

Subjects: Presenilin-1*/Presenilin-1*/Presenilin-1*/genetics ; Presenilin-1*/Presenilin-1*/Presenilin-1*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

• Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Jun 20; Vol. 20 (1), pp. 73. Date of Electronic Publication: 2025 Jun 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

Record details

KChIP3 fosters neuroinflammation and synaptic dysfunction in the 5XFAD mouse model of Alzheimer's disease.

• Authors : Arcos-Encarnación B; Laboratorio de Neuroinmunobiología, Departamento de Medicina Molecular y Bioprocesos, Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), 62210, Cuernavaca, Morelos, México.; Cortes-Flores E

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

• Source: Journal of neuroinflammation [J Neuroinflammation] 2025 Jun 19; Vol. 22 (1), pp. 160. Date of Electronic Publication: 2025 Jun 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

Record details

Investigating the Synergistic Neuroprotective Effects of Plant-Derived Antioxidants and the Psychedelic N,N-Dimethyltryptamine in Alzheimer's Disease Therapy.

• Authors : Jarne-Ferrer J; Department of Pharmacology and Therapeutic Chemistry, Institut de Neurociències, Universitat de Barcelona, Avda. Joan XXIII, 27, 08028 Barcelona, Spain.; Pallàs M

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Antioxidants*/Antioxidants*/Antioxidants*/pharmacology

• Source: Cells [Cells] 2025 Jun 19; Vol. 14 (12). Date of Electronic Publication: 2025 Jun 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

Record details