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Academic Journal

In vivo characterization of P388 leukemia resistant to mitomycin C

Authors : W C, Rose; J B, Huftalen; W T, Bradner

Subjects: 0303 health sciences; 03 medical and health sciences; Mice

Source: In vivo (Athens, Greece). 1(1)

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Academic Journal

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition

Authors : M. Prudhomme; Jonathan B. Chaires; David E. Graves

Subjects: Models, Molecular; 0301 basic medicine; Indoles

Source: Chemistry & Biology. 6:277-286

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Academic Journal

The Biosynthetic Gene Cluster for the Antitumor Rebeccamycin

Authors : Alfredo F. Braña; Jürgen Rohr; José A. Salas

Subjects: Pharmacology; 0301 basic medicine; Indoles

Source: Chemistry & Biology. 9:519-531

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Academic Journal

Combinatorial biosynthesis of antitumor indolocarbazole compounds

Authors : Lili Zhu; José A. Salas; Jürgen Rohr

Subjects: 0301 basic medicine; 03 medical and health sciences; Indoles

Source: Proceedings of the National Academy of Sciences. 102:461-466

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Academic Journal

Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC

Authors : Catherine L. Drennan; Michael J. Hamill; Christopher T. Walsh

Subjects: 0301 basic medicine; Indoles; Protein Conformation

Source: Proceedings of the National Academy of Sciences. 104:15311-15316

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Academic Journal

Rebeccamycin Derivatives as Dual DNA-Damaging Agents and Potent Checkpoint Kinase 1 Inhibitors

Authors : Marminon, Christelle; Anizon, Fabrice; Moreau, Pascale ...

Subjects: 0301 basic medicine; [SDV.BBM]Life Sciences [q-bio]/Biochemistry; Carbazoles

Source: Molecular PharmacologyMolecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2008, 74 (6), pp.1620-1629. ⟨10.1124/mol.108.049346⟩Molecular

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Academic Journal

Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells

Authors : Tomasz Obrzut; Orsolya Polgar; Suneet Shukla

Subjects: Adenosine Triphosphatases; Azides; Lung Neoplasms

Source: Cancer Chemotherapy and Pharmacology. 64:575-583

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Academic Journal

Phase II and pharmacokinetic trial of rebeccamycin analog in advanced biliary cancers

Authors : Ramesh K. Ramanathan; Afshin Dowlati; Smitha S. Krishnamurthi

Subjects: Male; 0301 basic medicine; Neutropenia

Source: Cancer Chemotherapy and Pharmacology. 65:73-78

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Academic Journal

A phase I study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors

Authors : Charles J. Nock; Brenda W. Cooper; Scot C. Remick

Subjects: Adult; Aged, 80 and over; Male

Source: Investigational New Drugs. 29:126-130

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Academic Journal

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

Authors : Francisco Morís; Verónica Corrales-Sánchez; Juan Carlos Montero ...

Subjects: 0301 basic medicine; Epithelial-Mesenchymal Transition; Blotting, Western

Source: Digital.CSIC. Repositorio Institucional del CSICConsejo Superior de Investigaciones Científicas (CSIC)instname

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