Source: American Journal of Physiology-Lung Cellular and Molecular Physiology, 318(4), L644-L654. AMER PHYSIOLOGICAL SOCAm J Physiol Lung Cell Mol Physiol

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An Anti-BCMA RNA Aptamer for miRNA Intracellular Delivery

Authors : Vittorio de Franciscis; Carla Lucia Esposito; Pierfrancesco Tassone

Subjects: 0301 basic medicine; medicine.drug_class; Aptamer

Source: Molecular Therapy: Nucleic Acids, Vol 18, Iss, Pp 981-990 (2019)MOLECULAR THERAPY-NUCLEIC ACIDS 18 (2019): 981–990. doi:10.1016/j.omtn.2019.10.021info:cnr-pdr/source/autori:Catuogno S.;

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Integrating Ligand-Receptor Interactions and In Vitro Evolution for Streamlined Discovery of Artificial Nucleic Acid Ligands

Authors : Roksana Azad; Sana Batool; Prabodhika Mallikaratchy

Subjects: 0301 basic medicine; medicine.drug_class; Aptamer

Source: Molecular Therapy. Nucleic AcidsMolecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 150-163 (2019)

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De novo ssRNA Aptamers against the SARS-CoV-2 Main Protease: In Silico Design and Molecular Dynamics Simulation

Authors : Ilaria Tortorella; Francesco Morena; Sabata Martino

Subjects: 0301 basic medicine; medicine.medical_treatment; Entropy

Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 22, Iss 6874, p 6874 (2021)Volume 22Issue 13

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Overview of the Therapeutic Potential of Aptamers Targeting Coagulation Factors

Authors : Yolanda M. Fortenberry; Max Liu; Khalequz Zaman

Subjects: 0301 basic medicine; Hematological disorders; Aptamer

Source: International Journal of Molecular Sciences, Vol 22, Iss 3897, p 3897 (2021)International Journal of Molecular Sciences

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Aptamers and antibodies: rivals or allies in cancer targeted therapy?

Authors : Lisa Agnello; Simona Camorani; Monica Fedele

Subjects: 0301 basic medicine; theranostics; lcsh:Internal medicine

Source: Exploration of Targeted Anti-tumor Therapy, Vol 2, Iss 1, Pp 107-121 (2021)

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The Roles of Sclerostin in Immune System and the Applications of Aptamers in Immune-Related Research

Authors : Meiheng Sun; Zihao Chen; Xiaoqiu Wu

Subjects: lcsh:Immunologic diseases. Allergy; 0301 basic medicine; T-Lymphocytes

Source: Frontiers in Immunology, Vol 12 (2021)Frontiers in Immunology

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The Relevance of the SH2 Domain for c-Src Functionality in Triple-Negative Breast Cancer Cells

Authors : Víctor Mayoral-Varo; Marta García-Hernández; María Pilar Sánchez-Bailón ...

Subjects: 0301 basic medicine; Cancer Research; Population

Source: Cancers, Vol 13, Iss 462, p 462 (2021)CancersVolume 13Issue 3Digital.CSIC. Repositorio Institucional del CSICinstname

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Biological Nanopores: Engineering on Demand

Authors : Marija Srnko; Ana Crnković; Gregor Anderluh

Subjects: 0301 basic medicine; Materials science; pore-forming toxins

Source: LifeLife, vol. 11, no. 1, 27, pp. 1-30, 2021.Life, Vol 11, Iss 27, p 27 (2021)

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Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs

Authors : Benjamin L. Oakes; Tanja Kortemme; Christof Fellmann

Subjects: 0301 basic medicine; CRISPR-Cas9 genome editing; Aptamer

Source: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)Kundert, Kale; Lucas, James E; Watters, Kyle E; Fellmann, Christof; Ng, Andrew H; Heineike, Benjamin M; et al.(2019). Controlling CRISPR-Cas9

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Isolation of MLL1 Inhibitory RNA Aptamers

Authors : Kwang Won Jeong; Kwang-Hoon Chun; Hwan-Mook Kim

Subjects: 0301 basic medicine; Methyltransferase; ssRNA

Source: Biomolecules & Therapeutics

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Targeting lung cancer initiating cells by all-trans retinoic acid-loaded lipid-PLGA nanoparticles with CD133 aptamers

Authors : Qingfeng Li; Jing Sun; Lu Huang

Subjects: 0301 basic medicine; Cancer Research; Cell

Source: Experimental and Therapeutic Medicine

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Lipid vesicles chaperone an encapsulated RNA aptamer

Authors : Ranajay Saha; Irene A. Chen; Samuel Verbanic

Subjects: 0301 basic medicine; Protocell; Models, Molecular

Source: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)Nature communications, vol 9, iss 1Nature Communications

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The Latest Achievements in the Construction of Influenza Virus Detection Aptasensors

Authors : Tomasz Wandtke; Ewelina Wędrowska; Elżbieta Piskorska

Subjects: 0301 basic medicine; 2019-20 coronavirus outbreak; Coronavirus disease 2019 (COVID-19)

Source: Viruses, Vol 12, Iss 1365, p 1365 (2020)Viruses

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Methods and Applications of In Silico Aptamer Design and Modeling

Authors : Alexey V. Samokhvalov; Anatoly V. Zherdev; Boris B. Dzantiev

Subjects: 0301 basic medicine; Molecular model; in silico design

Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 21, Iss 8420, p 8420 (2020)

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Connective Tissue Growth Factor: From Molecular Understandings to Drug Discovery

Authors : Ning Zhang; Yuanyuan Yu; Bao-Ting Zhang

Subjects: 0301 basic medicine; Angiogenesis; medicine.medical_treatment

Source: Frontiers in Cell and Developmental BiologyFrontiers in Cell and Developmental Biology, Vol 8 (2020)

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Nucleic acid-based therapy for coronavirus disease 2019

Authors : Keshav Rajarshi; Rajni Khan; Shashikant Ray

Subjects: 0301 basic medicine; Drug; Coronavirus disease 2019 (COVID-19)

Source: HeliyonHeliyon, Vol 6, Iss 9, Pp e05007-(2020)

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Aptamers and Antisense Oligonucleotides for Diagnosis and Treatment of Hematological Diseases

Authors : Viviana Izzo; Carmine Selleri; Valentina Giudice

Subjects: 0301 basic medicine; diagnosis; Aptamer

Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 21, Iss 3252, p 3252 (2020)

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A DNA Aptamer Based Method for Detection of SARS-CoV-2 Nucleocapsid Protein

Authors : Jing Chen; Xiaohua Ni; Jianfeng Dai

Subjects: 0301 basic medicine; 2019-20 coronavirus outbreak; Coronavirus disease 2019 (COVID-19)

Source: Frontiers in MicrobiologyVirologica Sinica

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A Review of Nanotechnology for Targeted Anti-schistosomal Therapy

Authors : Yahya E. Choonara; Tayo Alex Adekiya; Pierre P. D. Kondiah

Subjects: 0301 basic medicine; Drug; targeted agents

Source: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)Frontiers in Bioengineering and Biotechnology

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Aptamer-Conjugated Superparamagnetic Ferroarabinogalactan Nanoparticles for Targeted Magnetodynamic Therapy of Cancer

Authors : Ivan N. Lapin; V. N. Zabluda; Galina S. Zamay

Subjects: магнитно-резонансная томография; 0301 basic medicine; Cancer Research

Source: Cancers, Vol 12, Iss 1, p 216 (2020)CancersCancers. 2020. Vol. 12, № 1. P. 216 (1-17)Volume 12Issue 1

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Gluten Detection Methods and Their Critical Role in Assuring Safe Diets for Celiac Patients

Authors : Claudia E Osorio; Sachin Rustgi; Jaime H. Mejias

Subjects: 0301 basic medicine; medicine.medical_specialty; Food Safety

Source: Nutrients

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Aptamer-Based Proteomics Identifies Mortality-Associated Serum Biomarkers in Dialysis-Dependent AKI Patients

Authors : Richard D. Beger; Devasmita Choudhury; Paul M. Palevsky

Subjects: 0301 basic medicine; Oncology; medicine.medical_specialty

Source: Kidney International Reports

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Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

Authors : Tingting Zhao; Hong Xiaoqian; Yan Huihui

Subjects: Adult; Male; 0301 basic medicine

Source: Journal of Translational MedicineJournal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)

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Aptamers in the Therapeutics and Diagnostics Pipelines

Authors : Tarun Kumar Sharma; John G. Bruno; Amit Kumar

Subjects: 0301 basic medicine; clinical trials; Biological Products

Source: Theranostics

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Aptamer-Based Diagnostic Systems for the Rapid Screening of TB at the Point-of-Care

Authors : Martin O. Onani; Phumuzile Dube; Abram M. Madiehe

Subjects: 0301 basic medicine; Medicine (General); medicine.medical_specialty

Source: DiagnosticsDiagnostics, Vol 11, Iss 1352, p 1352 (2021)

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Diagnostics and Therapeutics in Targeting HER2 Breast Cancer: A Novel Approach

Authors : Giovanni Mandarano; Sarah Shigdar; Chris Vi

Subjects: 0301 basic medicine; Poor prognosis; Future studies

Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 22, Iss 6163, p 6163 (2021)

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In Situ Spatial Complementation of Aptamer-Mediated Recognition Enables Live-Cell Imaging of Native RNA Transcripts in Real Time

Authors : Zejun Wang; Xiaodong Xie; Lihua Wang

Subjects: 0301 basic medicine; Cytoplasm; Fluorescence-lifetime imaging microscopy

Source: Angewandte Chemie (International ed. in English), vol 57, iss 4Wang, Z; Luo, Y; Xie, X; Hu, X; Song, H; Zhao, Y; et al.(2018). In Situ Spatial Complementation of Aptamer-Mediated Recognition

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Aptamer-Based Therapeutic Approaches to Target Cancer Stem Cells

Authors : Liang Qiao; Mary Bagdesar; Wei Duan

Subjects: 0301 basic medicine; Aptamer; aptamers

Source: Theranostics

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RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes

Authors : Wafa Hassouneh; James M. Wagner; Hal S. Alper

Subjects: 0301 basic medicine; Streptavidin; High-throughput screening

Source: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)Nature communications, vol 8, iss 1Nature Communications

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Aptamers, Riboswitches, and Ribozymes in S. cerevisiae Synthetic Biology

Authors : Mario Andrea Marchisio; Huanhuan Ge

Subjects: riboswitches; 0301 basic medicine; Riboswitch

Source: LifeLife, Vol 11, Iss 248, p 248 (2021)

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Aptamers for CD Antigens: From Cell Profiling to Activity Modulation

Authors : Amin Nozari; Maxim V. Berezovski

Subjects: 0301 basic medicine; Small interfering RNA; Aptamer

Source: Molecular Therapy: Nucleic Acids, Vol 6, Iss, Pp 29-44 (2017)Molecular Therapy. Nucleic Acids

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In vitro evolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategies

Authors : Suxiang Chen; Farhana Lipi; Madhuri Chakravarthy

Subjects: 0301 basic medicine; Aptamer; Review

Source: RNA Biology

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AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments

Authors : Phuong Dao; Fabrizio Costa; Yijie Wang

Subjects: 0301 basic medicine; Histology; Sequence analysis

Source: Cell systems, vol 3, iss 1Dao, P; Hoinka, J; Takahashi, M; Zhou, J; Ho, M; Wang, Y; et al.(2016). AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX

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Therminator DNA Polymerase: Modified Nucleotides and Unnatural Substrates

Authors : William E. Jack; Madeleine M. Boyle; Jackson Buss

Subjects: 0301 basic medicine; DNA polymerase; Aptamer

Source: Frontiers in Molecular Biosciences, Vol 6 (2019)Frontiers in Molecular Biosciences

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Axl-Targeted Delivery of the Oncosuppressor miR-137 in Non-small-Cell Lung Cancer

Authors : Maria Capuozzo; Carla Lucia Esposito; Serena Boccella ...

Subjects: 0301 basic medicine; medicine.medical_treatment; aptamers

Source: Molecular Therapy. Nucleic AcidsMOLECULAR THERAPY-NUCLEIC ACIDS 17 (2019): 256–263. doi:10.1016/j.omtn.2019.06.002info:cnr-pdr/source/autori:Nuzzo S.; Catuogno S.; Capuozzo M.; Fiorelli

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Development of DNA Aptamers to Native EpCAM for Isolation of Lung Circulating Tumor Cells from Human Blood

Authors : Maxim V. Berezovski; Tatiana N Zamay; Anna S. Kichkailo

Subjects: 0301 basic medicine; Cancer Research; Aptamer

Source: CancersVolume 11Issue 3Cancers, Vol 11, Iss 3, p 351 (2019)Cancers. 2019. Vol. 11, № 3. P. 351 (1-14)

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Comparison of Effects of Anti-thrombin Aptamers HD1 and HD22 on Aggregation of Human Platelets, Thrombin Generation, Fibrin Formation, and Thrombus Formation Under Flow Conditions

Authors : Derszniak, Katarzyna; Przyborowski, Kamil; Matyjaszczyk, Karolina ...

Subjects: 0301 basic medicine; fibrin generation; VON-WILLEBRAND-FACTOR

Source: Frontiers in PharmacologyFrontiers in Pharmacology, 10:68. Frontiers Media S.A.Frontiers in Pharmacology, Vol 10 (2019)

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Nucleic Acid Aptamers Targeting Epigenetic Regulators: An Innovative Therapeutic Option

Authors : Carla Lucia Esposito; Vittorio de Franciscis; Silvia Catuogno

Subjects: 0301 basic medicine; Aptamer; aptamers

Source: PharmaceuticalsPharmaceuticals, Vol 11, Iss 3, p 79 (2018)Pharmaceuticals (Basel) 11 (2018). doi:10.3390/ph11030079info:cnr-pdr/source/autori:Catuogno S.; Esposito C.L.; Ungaro P.;

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Molecular Modeling Applied to Nucleic Acid-Based Molecule Development

Authors : Carsten Wrenger; Flavia M. Zimbres; Thales Kronenberger

Subjects: Models, Molecular; 0301 basic medicine; Molecular model

Source: Biomolecules, Vol 8, Iss 3, p 83 (2018)Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)Universidade de São Paulo (USP)instacron:USPBiomolecules

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