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USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1

Authors : Wu Ye; Yuluo Rong; Wei Liu

Subjects: Gene knockdown; Programmed cell death; Spinal Cord Ischemia

Source: Cell Death Differ

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Loss of Acot12 contributes to NAFLD independent of lipolysis of adipose tissue

Authors : In Jeoung Baek; Dae Won Jun; Brian Raught

Subjects: Male; 0301 basic medicine; medicine.medical_specialty

Source: Experimental & Molecular Medicine

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DUB’ling down uncovers an X-linked vulnerability in Alzheimer’s disease

Authors : Bindu D. Paul

Subjects: Deubiquitinating Enzymes; Tauopathies; Alzheimer Disease

Source: Cell

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Production of 1-octanol in Escherichia coli by a high flux thioesterase route

Authors : Ke Xu; Michael A. Jindra; Néstor J. Hernández Lozada

Subjects: 0106 biological sciences; Fatty alcohol; Bioengineering

Source: Metab Eng

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Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease

Authors : Jonathan D. Cooper; Thomas M. Wishart; Maica Llavero Hurtado

Subjects: Batten disease; Proteome; Protein Array Analysis

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)Scientific ReportsNelvagal, H R, Llavero Hurtado, M, Eaton, S, Kline, R, Lamont, D J, Sands, M S, Wishart, T & Cooper, J D 2020, '

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Metabolic engineering of β-oxidation to leverage thioesterases for production of 2-heptanone, 2-nonanone and 2-undecanone

Authors : Michael A. Jindra; Qiang Yan; Xuanqi Chen

Subjects: 0106 biological sciences; Ketone; Lignocellulosic biomass

Source: Metab Eng

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Ppt1-deficiency dysregulates lysosomal Ca(++)-homeostasis contributing to pathogenesis in a mouse model of CLN1 disease

Authors : Avisek Mondal; Abhilash P. Appu; Tamal Sadhukhan

Subjects: Mice, Knockout; Membrane Proteins; Article

Source: J Inherit Metab Dis

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Aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase

Authors : Shan Wang; William D. G. Brittain; Qian Zhang

Subjects: TP; Multidisciplinary; Science

Source: Nature CommunicationsNature Communications, 2022, Vol.13(1) [Peer Reviewed Journal]Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

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PPARα−ACOT12 axis is responsible for maintaining cartilage homeostasis through modulating de novo lipogenesis

Authors : Sujeong Park; In-Jeoung Baek; Ji Hyun Ryu

Subjects: Cartilage, Articular; Multidisciplinary; Science

Source: Nature CommunicationsNature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

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Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair

Authors : Elizabeth R. Dufficy; Karan Sharma; Maria Pilar Sanchez-Bailon

Subjects: Protein-Arginine N-Methyltransferases; Methyltransferase; Ubiquitylation

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)Nature Communications

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