Search Results

Integrated genomic and molecular characterization of cervical cancer.

• Authors : Cancer Genome Atlas Research Network; Albert Einstein College of Medicine; Analytical Biological Services

Subjects: Cancer Genome Atlas Research Network; Albert Einstein College of Medicine; Analytical Biological Services

• Source: Nature. 543(7645)

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Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2

• Authors : Silvestri, Valentina; Barrowdale, Daniel; Mulligan, Anna Marie

Subjects: Biomedical and Clinical Sciences; Clinical Sciences; Oncology and Carcinogenesis

• Source: Breast Cancer Research. 18(1)

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Interferons reshape the 3D conformation and accessibility of macrophage chromatin

• Authors : Ekaterini Platanitis (Centre for Molecular Biology, University of Vienna); Stephan Gruener (Centre for Molecular Biology, University of Vienna); Aarathy Ravi Sundar Jose Geetha (Centre for Molecular Biology, University of Vienna)

Subjects: Molecular biology; Molecular mechanism of gene regulation; Epigenetics

• Source: iScience ; issn:2589-0042

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TBCRC 019: A Phase II Trial of Nanoparticle Albumin-Bound Paclitaxel with or without the Anti-Death Receptor 5 Monoclonal Antibody Tigatuzumab in Patients with Triple-Negative Breast Cancer

• Authors : Forero-Torres, Andres; Consortium, on behalf of the Translational Breast Cancer Research; Varley, Katherine E

Subjects: Clinical Research; Cancer; Breast Cancer

• Source: Clinical Cancer Research. 21(12)

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PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma

• Authors : Himanshu Soni (Brain Tumor Translational Targets, DKFZ Junior Group, German Cancer Research Center (DKFZ)); Julia Bode (Molecular Mechanisms of Tumor Invasion, Schaller Research Group, University of Heidelberg and German Cancer Research Center (DKFZ)); Chi D. L. Nguyen (Leibniz-Institut für Analytische Wissenschaften—ISAS—e.V.)

Subjects: Cancer Research; Molecular Biology

• Source: Oncogenesis ; issn:2157-9024

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Demonstrating trustworthiness when collecting and sharing genomic data: public views across 22 countries

• Authors : Richard Milne (Society and Ethics Research Group, Wellcome Connecting Science); Katherine I. Morley (RAND Europe); Mohamed A. Almarri (Wellcome Sanger Institute)

Subjects: Genetics (clinical); Genetics; Molecular Biology

• Source: Genome Medicine ; issn:1756-994X

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Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study.

• Authors : Schrijver, Lieske H; Antoniou, Antonis C; Olsson, Håkan

Subjects: BRCA1; BRCA2; epidemiology

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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

• Authors : Bojesen, Stig E; Pooley, Karen A; Johnatty, Sharon E

Subjects: Australian Cancer Study; Australian Ovarian Cancer Study; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer

• Source: Nature genetics. 45(4)

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Current opportunities to catalyze research in nutrition and cancer prevention – an interdisciplinary perspective

• Authors : The Cancer Research UK - Ludwig Cancer Research Nutrition and Cancer Prevention Collaborative Group

Subjects: Cancer prevention; Developmental origins; Diet

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The use of digital pathology and image analysis in clinical trials.

• Authors : Pell, R; Oien, K; Robinson, M ...

Subjects: UK National Cancer Research Institute (NCRI) Cellular-Molecular Pathology (CM-Path) quality assurance working group; Humans; Image Interpretation

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Training and accreditation standards for pathologists undertaking clinical trial work.

• Authors : Rees, G; Salto-Tellez, M; Lee, JL ...

Subjects: National Cancer Research Institute (NCRI) Cellular-Molecular Pathology (CM-Path) clinical trials working group; Humans; Reproducibility of Results

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Guidelines for the welfare and use of animals in cancer research.

• Authors : Workman, P; Aboagye, EO; Balkwill, F

Subjects: Committee of the National Cancer Research Institute; Cell Line; Transformed

• Source: British journal of cancer. 102(11)

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Moving AHEAD with an international human epigenome project.

• Authors : American Association for Cancer Research Human Epigenome Task Force; European Union, Network of Excellence, Scientific Advisory Board

Subjects: American Association for Cancer Research Human Epigenome Task Force; European Union; Network of Excellence

• Source: Nature. 454(7205)

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Assessing the Impact of the COVID-19 Pandemic on Emergency Department Use for Patients Undergoing Cancer-Directed Surgeries

• Authors : Antoine, Eskander; Qing, Li; Jiayue, Yu

Subjects: Ontario; cancer; surgery

• Source: Current Oncology; Volume 29; Issue 3; Pages: 1877-1889

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Hydroxycarbamide Plus Aspirin Versus Aspirin Alone in Patients With Essential Thrombocythemia Age 40 to 59 Years Without High-Risk Features.

• Authors : Godfrey, Anna L; Campbell, Peter J; MacLean, Cathy

Subjects: Adult; Aspirin; Australia

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New horizons in breast cancer: the promise of immunotherapy.

• Authors : de la Cruz-Merino, L; Palazón-Carrión, N; Henao-Carrasco, F

Subjects: Breast; Cancer; Clinical

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Quality assurance guidance for scoring and reporting for pathologists and laboratories undertaking clinical trial work.

• Authors : Robinson, M; James, J; Thomas, G ...

Subjects: UK National Cancer Research Institute (NCRI) Cellular-Molecular Pathology (CM-Path) clinical trials working group; Humans; Neoplasm

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Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

• Authors : Silvestri, V; Barrowdale, D; Mulligan, AM ...

Subjects: kConFab Investigators; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); EMBRACE

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Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer.

• Authors : Shlien, Adam; Raine, Keiran; Fuligni, Fabio

Subjects: Algorithms; Breast Neoplasms; Data Interpretation

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Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

• Authors : Fehringer, Gordon; Kraft, Peter; Pharoah, Paul D

Subjects: Breast Neoplasms; Colorectal Neoplasms; Female

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Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

• Authors : Lawrenson, K; Kar, S; McCue, K ...

Subjects: GEMO Study Collaborators; EMBRACE; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON)

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Skeletal muscle mass correlates with increased toxicity during neoadjuvant radiochemotherapy in locally advanced esophageal cancer: A SAKK 75/08 substudy

• Authors : Cédric M. Panje; Laura Höng; Stefanie Hayoz ...

Subjects: Male; Oncology; Sarcopenia

• Source: Radiation Oncology, Vol 14, Iss 1, Pp 1-7 (2019)Radiation Oncology (London, England)Panje, Cédric M; Höng, Laura; Hayoz, Stefanie; Baracos, Vickie E; Herrmann, Evelyn; Garcia Schüler,

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Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10)

• Authors : F. Hitz; M. Kraus; T. Pabst

Subjects: Adult; Male; medicine.medical_specialty

• Source: Blood Cancer Journal, Vol 9, Iss 9, Pp 1-8 (2019)Hitz, F; Kraus, M; Pabst, Thomas; Hess, D; Besse, L; Silzle, T; Novak, Urban; Seipel, Katja; Rondeau, S; Stüdeli,

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Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy.

• Authors : Despierre, Evelyn; Vergote, Ignace; Anderson, Ryan

Subjects: Biomarkers, Tumor; Organoplatinum Compounds; Protein Kinase Inhibitors

• Source: Targeted Oncology, 10 (4), 583 - 596 (2015-12)

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Training and accreditation standards for pathologists undertaking clinical trial work

• Authors : Gabrielle Rees; Manuel Salto‐Tellez; Jessica L Lee

Subjects: education; Translational research; Pathology and Forensic Medicine

• Source: The Journal of Pathology: Clinical Researchon behalf of the National Cancer Research Institute (NCRI)

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Subclonal TP53 copy number is associated with prognosis in multiple myeloma.

• Authors : Shah, V; Johnson, DC; Sherborne, AL ...

Subjects: National Cancer Research Institute Haematology Clinical Studies Group; Humans; Multiple Myeloma

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Preoperative chemotherapy and radiotherapy concomitant to cetuximab in resectable stage IIIB NSCLC: a multicentre phase 2 trial (SAKK 16/08)

• Authors : Curioni-Fontecedro, Alessandra; Perentes, Jean Yannis; Gelpke, Hans ...

Subjects: Oncology; Adult; Male

• Source: British journal of cancer, vol. 120, no. 10, pp. 968-974British Journal of Cancer, Vol. 120, No 10 (2019) pp. 968-974British

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High thromboembolic event rate in patients with locally advanced oesophageal cancer during neoadjuvant therapy. An exploratory analysis of the prospective, randomised intergroup phase III trial SAKK 75/08

• Authors : Martin Fehr; Hanne Hawle; Stefanie Hayoz

Subjects: Male; Cancer Research; Esophageal Neoplasms

• Source: BMC CancerBMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)

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Randomized study comparing full dose monotherapy (S-1 followed by irinotecan) and reduced dose combination therapy (S-1/oxaliplatin followed by S-1/irinotecan) as initial therapy for older patients with metastatic colorectal cancer: NORDIC 9

• Authors : Stine Braendegaard Winther; Pia Österlund; Åke Berglund ...

Subjects: 0301 basic medicine; Oncology; Male

• Source: BMC Cancer, Vol 17, Iss 1, Pp 1-7 (2017)Winther, S B, Österlund, P, Berglund, Å, Glimelius, B, Qvortrup, C, Sorbye, H, Pfeiffer, P & on behalf of the Academy of

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Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML

• Authors : Löwenberg, Bob; Pabst, Thomas; Maertens, Johan ...

Subjects: 1303 Biochemistry; PROGNOSIS; medicine.medical_treatment

• Source: Löwenberg, B, Pabst, T, Maertens, J, Van Norden, Y, Biemond, B J, Schouten, H C, Spertini, O, Vellenga, E, Graux, C, Havelange, V, De Greef, G E, De Weerdt, O, Legdeur, M C J C, Kuball, J, Van

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Quality assurance guidance for scoring and reporting for pathologists and laboratories undertaking clinical trial work

• Authors : Max Robinson; Jacqueline James; Gareth Thomas

Subjects: 0301 basic medicine; medicine.medical_specialty; Neoplasm, Residual

• Source: The Journal of Pathology: Clinical Research, Vol 5, Iss 2, Pp 91-99 (2019)on behalf of the UK National Cancer

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The use of digital pathology and image analysis in clinical trials

• Authors : Robert Pell; Karin Oien; Max Robinson

Subjects: Computer science; Telepathology; Remote learning

• Source: on behalf of the UK National Cancer Research Institute (NCRI) Cellular-Molecular Pathology (CM-Path) quality assurance working group 2019,

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Neoadjuvant degarelix with or without apalutamide followed by radical prostatectomy for intermediate and high-risk prostate cancer: ARNEO, a randomized, double blind, placebo-controlled trial

• Authors : Lorenzo Tosco; Annouschka Laenen; Thomas Gevaert

Subjects: 0301 basic medicine; Biochemical recurrence; Male

• Source: BMC CancerBMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)BMC cancer, 18 (1

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Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

• Authors : Michailidou, K; Hall, P; Gonzalez-Neira, A ...

Subjects: Breast and Ovarian Cancer Susceptibility Collaboration; Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON); kConFab Investigators

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Extended adjuvant aromatase inhibition after sequential endocrine therapy (DATA): a randomised, phase 3 trial

• Authors : Tjan-Heijnen, Vivianne C G; van Hellemond, Irene E G; Peer, Petronella G M ...

Subjects: Administration; Oral; Adult

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Combination of bevacizumab and 2-weekly pegylated liposomal doxorubicin as first-line therapy for locally recurrent or metastatic breast cancer. A multicenter, single-arm phase II trial (SAKK 24/06)

• Authors : Rochlitz, C; Ruhstaller, T; Lerch, S ...

Subjects: Oncology; medicine.medical_specialty; genetic structures

• Source: Rochlitz, C; Ruhstaller, T; Lerch, S; Spirig, C; Huober, J; Suter, T; Bühlmann, M; Fehr, M; Schönenberger, A; von Moos, R; Winterhalder, R; Rauch, D; Müller, A; Mannhart-Harms, M; Herrmann, R;

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External beam radiotherapy for unresectable hepatocellular carcinoma, an international multicenter phase I trial, SAKK 77/07 and SASL 26

• Authors : Bigler, Martin; Ciernik, Ilja; Buijsen, Jeroen ...

Subjects: Male; Hepatocellular carcinoma; medicine.medical_treatment

• Source: Radiation Oncology, 12:12. BioMed Central LtdHerrmann, Evelyn; Naehrig, Diana; Sassowsky, Manfred; Bigler, Martin; Buijsen, Jeroen; Ciernik, Ilja; Zwahlen, Daniel; Pellanda, Alessandra

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Azacytidine for acute myeloid leukemia in elderly or frail patients: a phase II trial (SAKK 30/07)

• Authors : Passweg Jakob R; Pabst Thomas; Blum Sabine

Subjects: Male; Antimetabolites, Antineoplastic; Cancer Research

• Source: Leukemia & lymphomaLeukemia and Lymphoma, Vol. 55, No 1 (2014) pp. 87-91

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Immediate versus deferred chemotherapy after radical cystectomy in patients with pT3-pT4 or N+ M0 urothelial carcinoma of the bladder (EORTC 30994): an intergroup, open-label, randomised phase 3 trial

• Authors : Sternberg, Cora N; Skoneczna, Iwona; Kerst, J Martijn ...

Subjects: Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Europe

• Source: The Lancet Oncology, Vol. 16, no.1, p. 76-86 (2015)

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First-line temozolomide combined with bevacizumab in metastatic melanoma: a multicentre phase II trial (SAKK 50/07)

• Authors : Von Moos, R; Seifert, B; Simcock, M ...

Subjects: Oncology; Adult; Male

• Source: Annals of Oncology, vol. 23, no. 2, pp. 531-6von Moos, R; Seifert, B; Simcock, M; Goldinger, S M; Gillessen, S; Ochsenbein, A; Michielin, O; Cathomas, R; Schläppi, M; Moch, H; Schraml, P H;

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Favorable effect of priming with granulocyte colony-stimulating factor in remission induction of acute myeloid leukemia restricted to dose escalation of cytarabine

• Authors : Pabst, Thomas; Vellenga, Edo; van Putten, Wim

Subjects: Adult; Antimetabolites; Antineoplastic

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Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

• Authors : Ley, Timothy; Miller, Christopher; Ding, Li

Subjects: Myeloid; Adult; Epigenomics

• Source: The New England journal of medicine. 368(22)

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Building capacity for clinical research in developing countries: the INDOX Cancer Research Network experience

• Authors : Raghib Ali; Alexander Finlayson; on behalf of the INDOX Cancer Research Network

Subjects: Economic growth; Capacity Building; Internationality

• Source: Global Health Action, Vol 5, Iss 0, Pp 1-6 (2012)Global Health Action; Vol 5 (2012): incl SupplementsGlobal Health Action

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Special listing of current cancer research on carcinogenic substances in food and drugs (along with related epidemiology) /

• Authors : Smithsonian Science Information Exchange. Current Cancer Research Project Analysis Center.; International Cancer Research Data Bank.; National Cancer Institute (U.S.)

Subjects: Carcinogenesis; Carcinogenicity testing; Food

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Carcinogenesis : a broad critique : a collection of papers presented at the twentieth annual symposium on fundamental cancer research, 1966

• Authors : SYMPOSIUM ON FUNDAMENTAL CANCER RESEARCH (20º: 1966: Houston)

Subjects: Carcinogénesis

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Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma

• Authors : Weder, W; Stahel, RA; Bernhard, J ...

Subjects: Extrapleural Pneumonectomy; Adult; Male

• Source: Annals of Oncology, Vol. 18, No 7 (2007) pp. 1196-202Weder, W; Stahel, RA; Bernhard, J; Bodis, S; Vogt, P; Ballabeni, P; Lardinois, D; Betticher, D; Schmid, R; Stupp, R; Ris, HB; Jermann, M;

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Involvement of the tumour necrosis factor receptor system in glioblastoma cell death induced by palbociclib-heptamethine cyanine dye conjugate

• Authors : Cooper, Elizabeth; Oyagawa, Caitlin R. M.; Johnson, Rebecca ...

Subjects: Cell Biology; Molecular Biology; Biochemistry

• Source: Cell Communication and Signaling ; volume 22, issue 1 ; ISSN 1478-811X

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Mechanisms of RNF168 nucleosome recognition and ubiquitylation

• Authors : Hu, Qi; Zhao, Debiao; Cui, Gaofeng ...

Subjects: Cell Biology; Molecular Biology

• Source: Molecular Cell ; volume 84, issue 5, page 839-853.e12 ; ISSN 1097-2765

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Biological function, topology, and quantification of plasma membrane Ceramide

• Authors : Canals, Daniel; Hannun, Yusuf A.;

Subjects: Cancer Research; Genetics; Molecular Biology

• Source: Advances in Biological Regulation ; volume 91, page 101009 ; ISSN 2212-4926

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EGFR Exon-Level Biomarkers of the Response to Bevacizumab/Erlotinib in Non-Small Cell Lung Cancer

• Authors : Florent Baty; Sacha Rothschild; Martin Früh

Subjects: Male; Vascular Endothelial Growth Factor A; Lung Neoplasms

• Source: PLoS ONE, Vol 8, Iss 9, p e72966 (2013)Baty, Florent; Rothschild, Sacha; Früh, Martin; Betticher, Daniel; Dröge, Cornelia; Cathomas, Richard; Rauch, Daniel; Gautschi, Oliver; Bubendorf, Lukas;

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