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Altered levels of cyclic nucleotides, cyclic AMP phosphodiesterase and adenylyl cyclase activities in normal, dysplastic and neoplastic human mammary tissue

Authors : U. Eppenberger; J. Preisz; E. Geyer

Subjects: Biophysics; Breast Neoplasms; Biochemistry

Source: FEBS Letters. (1):102-106

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A randomized, double-blinded, placebo-controlled, crossover study of the HCN channel blocker ivabradine in a capsaicin-induced pain model in healthy volunteers

Authors : Satoshi, Tanaka; Takashi, Ishida; Kumiko, Ishida

Subjects: Adult; Male; Analgesics

Source: Scientific Reports. 12

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Refractoriness of STING therapy is relieved by AKT inhibitor through effective vascular disruption in tumour

Authors : Gou Young Koh; Seung-hwan Jeong; Myung Jin Yang

Subjects: 0301 basic medicine; Male; General Physics and Astronomy

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)Nature Communications

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Crucial role of stimulator of interferon genes-dependent signaling in house dust mite extract-induced IgE production

Authors : Tomoya Narita; Haruyuki Ishii; Hiroki Nunokawa

Subjects: 0301 basic medicine; Cell biology; T Follicular Helper Cells

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)Scientific Reports

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CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of TH1 and TH9 cells

Authors : Benoit-Lizon, Isis; Jacquin, Elise; Rivera Vargas, Thaiz ...

Subjects: CD4-Positive T-Lymphocytes; CD4-positive T lymphocytes; [SDV]Life Sciences [q-bio]

Source: Journal for Immunotherapy of CancerJournal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)Journal for Immunotherapy of Cancer, 2022, 10, ⟨10.1136/jitc-2021-003459⟩

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A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge

Authors : Jiangli Liang; Guang Ji; Jingyan Li

Subjects: Male; medicine.medical_treatment; nucleocapsid

Source: Cell Reports, Vol 37, Iss 11, Pp 110112-(2021)Cell Reports

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cGAS-like receptors: new RNA sensors in Drosophila

Authors : Yao Fan; Fangfang Zhou; Long Zhang

Subjects: Male; Models, Molecular; Cancer Research

Source: Signal Transduction and Targeted TherapySignal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-2 (2021)

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Inhibition of mTOR suppresses IFNα production and the STING pathway in monocytes from systemic lupus erythematosus patients

Authors : Taiga Kuga; Ken Yamaji; Asako Chiba

Subjects: Adult; Male; 0301 basic medicine

Source: Rheumatology. 59:2992-3002

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Angiotensin peptide synthesis and cyclic nucleotide modulation in sympathetic stellate ganglia

Authors : Emma N. Bardsley; David J. Paterson; Oliver C. Neely

Subjects: Adult; Male; 0301 basic medicine

Source: Journal of Molecular and Cellular Cardiology

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Combination therapy targeting both innate and adaptive immunity improves survival in a pre-clinical model of ovarian cancer

Authors : Adrian Bertschi; Carolin Andresen; Emily M. Cheney

Subjects: CD4-Positive T-Lymphocytes; 0301 basic medicine; Cancer Research

Source: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)Journal for Immunotherapy of Cancer

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