Search Results

Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer.

• Authors : Rugo, Hope; Campbell, Mike; Yau, Christina

Subjects: Breast cancer; Clinical trial; Colony-stimulating factor-1

• Source: Breast Cancer Research and Treatment. 209(3)

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Olorofim demonstrates in vitro activity against Coccidioides species, including isolates against which fluconazole has reduced activity.

• Authors : Wiederhold, Nathan; Patterson, Hoja; Ferrer, Dora

Subjects: Coccidioides species; fluconazole; in vitro susceptibility

• Source: Antimicrobial Agents and Chemotherapy. 69(1)

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A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents.

• Authors : Barnes, Griffin; Magann, Nicholas; Perrotta, Daniele

Subjects: Alkaloids; Plasmodium falciparum; Antiprotozoal Agents

• Source: Journal of the American Chemical Society. 146(43)

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Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents

• Authors : Amira Ibrahim Sayed; Shima Mahmoud Ali; Rania H. Abd El-Hameed

Subjects: Antifungal; Antifungal Agents; synthesis

• Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 2183-2198 (2021)Journal of Enzyme Inhibition and Medicinal Chemistryarticle-version (VoR) Version of Record

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Design, synthesis, in silico and biological evaluations of novel polysubstituted pyrroles as selective acetylcholinesterase inhibitors against Alzheimer’s disease

• Authors : Hormoz, Pourtaher; Alireza, Hasaninejad; Aida, Iraji

Subjects: Molecular Docking Simulation; Structure-Activity Relationship; Multidisciplinary

• Source: Scientific Reports. 12

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Two calix[4]pyrroles as potential therapeutics for castration-resistant prostate cancer

• Authors : Imene Ben Toumia; Marco Ponassi; Paola Barboro

Subjects: Pharmacology; Male; Cancer

• Source: Investigational new drugs. 40(6)

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Marizomib for patients with newly diagnosed glioblastoma: A randomized phase 3 trial

• Authors : Roth, Patrick; Gorlia, Thierry; Reijneveld, Jaap C

Subjects: Biomedical and Clinical Sciences; Clinical Sciences; Oncology and Carcinogenesis

• Source: Neuro-Oncology. 26(9)

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Differential susceptibility of cells infected with defective and intact HIV proviruses to killing by obatoclax and other small molecules

• Authors : Kadiyala, Gayatri Nikhila; Telwatte, Sushama; Wedrychowski, Adam

Subjects: Medical Microbiology; Biomedical and Clinical Sciences; Immunology

• Source: AIDS. 38(9)

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Antifungal Activity of Fibrate-Based Compounds and Substituted Pyrroles That Inhibit the Enzyme 3-Hydroxy-methyl-glutaryl-CoA Reductase of

• Authors : Damián A, Madrigal-Aguilar; Adilene, Gonzalez-Silva; Blanca, Rosales-Acosta

Subjects: Antifungal Agents; Fibric Acids; COVID-19

• Source: Microbiology spectrum. 10(2)

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A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents

• Authors : Giampietro Viola; Paola Oliva; Stefano Manfredini

Subjects: Antimitotic agents; Antiproliferative activity; Drug Screening Assays

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