Search Results

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy

• Authors : Ueno, Daiki; Vasquez, Juan C; Sule, Amrita

Subjects: Biomedical and Clinical Sciences; Oncology and Carcinogenesis; Cancer

• Source: Oncotarget. 13(1)

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Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

• Authors : Kurmasheva, Naziia; Said, Aida; Wong, Boaz

Subjects: Animals; Humans; Oncolytic Virotherapy/methods

• Source: Kurmasheva , N , Said , A , Wong , B , Kinderman , P , Han , X , Rahimic , A H F , Kress , A , Carter-Timofte , M E , Holm , E , van der Horst , D , Kollmann , C F , Liu , Z , Wang , C , Hoang , H-D ,

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Synthesis and study of the cancer cell growth inhibitory properties of alpha-, gamma-tocopheryl and gamma-tocotrienyl 2-phenylselenyl succinates

• Authors : Vraka, Panayiota S.; Drouza, Chryssoula; Rikkou, Maria P. ...

Subjects: Succinate; Cancer cells; Magnetic Resonance Spectroscopy

• Source: Bioorganic and Medicinal ChemistryBioorg.Med.Chem.

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MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat

• Authors : Purdy, Michael D; Shi, Dan; Chrustowicz, Jakub

Subjects: HIV/AIDS; Infectious Diseases; Infection

• Source: Proceedings of the National Academy of Sciences of the United States of America. 115(52)

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4-Octyl itaconate reduces influenza A replication by targeting the nuclear export protein CRM1

• Authors : Ribo-Molina, Pau; Weiss, Hauke J.; Susma, Balasubramanian

Subjects: Science & Technology; Life Sciences & Biomedicine; Virology

• Source: ISSN:0022-538X ; ISSN:1098-5514 ; Journal Of Virology, vol. 97 (10), Art.No. ARTN e0132523.

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The ad hoc chemical design of random PBS-based copolymers influences the activation of cardiac differentiation while altering the HYPPO pathway target genes in hiPSCs

• Authors : Guidotti, Giulia; Duelen, Robin; Bloise, Nora

Subjects: Science & Technology; Technology; Materials Science

• Source: ISSN:2772-9516 ; ISSN:2772-9508 ; Biomaterials Advances, vol. 154, Art.No. ARTN 213583.

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Itaconate controls its own synthesis via feedback-inhibition of reverse TCA cycle activity at IDH2.

• Authors : Heinz, Alexander; Nonnenmacher, Yannic; Henne, Antonia

Subjects: 2-hydroxyglutarate; Mitochondrial metabolism; Proinflammatory macrophage

• Source: Biochimica et Biophysica Acta - Molecular Basis of Disease, 1868 (12), 166530 (2022-12-01)

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Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

• Authors : Sohail, Aaqib; Iqbal, Azeem A; Sahini, Nishika

Subjects: article; Hochschulbibliographie allgemein; Verzeichnis wissenschaftlicher Veröffentlichungen2022

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Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes.

• Authors : Ceperuelo-Mallafré, Victòria; Reverté, Laia; Peraire, Joaquim

Subjects: COVID-19; energy-related metabolites; fluorometric quantification

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Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation.

• Authors : Chen, Xuyong; Sunkel, Benjamin; Wang, Meng

Subjects: Cell Proliferation; Chromatin; Electron Transport Complex II

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