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Academic Journal

Multi-Year Registry Study of Elapegademase Treatment in Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID) Requiring Enzyme Replacement Therapy.

Authors : Dorsey, Morna; Butte, Manish; Lieberman, Jay

Subjects: ADA-SCID; Elapegademase; Enzyme Replacement

Source: Journal of Clinical Immunology. 45(1)

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Academic Journal

Two-year follow-up of gait and postural control following initiation of recombinant human tripeptidyl intracerebroventricular enzyme replacement therapy in two atypical CLN2 patients.

Authors : Soangra, Rahul; Grant-Beuttler, Marybeth; Chang, Harriet

Subjects: Humans; Neuronal Ceroid-Lipofuscinoses; Enzyme Replacement Therapy

Source: Scientific Reports. 15(1)

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Academic Journal

Hepatic angiotensin-converting enzyme 2 expression in metabolic dysfunction-associated steatotic liver disease and in patients with fatal COVID-19

Authors : Jacobs, Angus K; Morley, Steven D; Samuel, Kay

Subjects: Male; Adult; Liver Cirrhosis

Source: World J Gastroenterol

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Academic Journal

Safety, pharmacokinetics, and pharmacodynamics of efzimfotase alfa, a second-generation enzyme replacement therapy: phase 1, dose-escalation study in adults with hypophosphatasia

Authors : Kathryn M Dahir; Amy Shannon; Derek Dunn

Subjects: Adult; Male; 0301 basic medicine

Source: J Bone Miner Res

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Academic Journal

Dose optimization of pancreatic enzyme replacement therapy is essential to mitigate muscle loss in patients with advanced pancreatic cancer and exocrine pancreatic insufficiency

Authors : Pamela N. Klassen; Vera C. Mazurak; Vickie Baracos

Subjects: Male; Sarcopenia; Dose-Response Relationship, Drug

Source: Clinical Nutrition. 43:1900-1906

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Academic Journal

Altered Liver Enzyme Markers in Patients with Asymptomatic, and Mild Omicron Infection: A Retrospective Study

Authors : Cao X; Xie YL; Yi JY

Subjects: omicron variant; ‘abnormal liver enzyme markers’; male

Source: Journal of Inflammation Research, Vol Volume 17, Pp 6875-6885 (2024)

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Academic Journal

In Vitro Metabolism and p53 Activation of Genotoxic Chemicals: Abiotic CYP Enzyme vs Liver Microsomes

Authors : Luise Henneberger; Julia Huchthausen; Jenny Braasch

Subjects: Male; Activation, Metabolic; Cytochrome P-450 Enzyme System

Source: Chem Res Toxicol

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Academic Journal

Insulin‐degrading enzyme inhibition increases the unfolded protein response and favours lipid accumulation in the liver

Authors : Andres, Marine; Hennuyer, Nathalie; Zibar, Khamis ...

Subjects: Male; Mice, Knockout; 0303 health sciences

Source: British Journal of PharmacologyBritish Journal of Pharmacology, 2024, 181 (19), pp.3610-3626. ⟨10.1111/bph.16436⟩

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Academic Journal

Identification of Nontuberculous Mycobacterium Species by Polymerase Chain Reaction - Restriction Enzyme Analysis (PCR-REA) of rpoB gene in Clinical Isolates

Authors : Raj Narayan Yadav; Yellanki Yashwanth Chowdary; Manpreet Bhalla

Subjects: nontuberculous mycobacteria; DNA, Bacterial; Male

Source: International Journal of Mycobacteriology, Vol 13, Iss 3, Pp 307-313 (2024)

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Academic Journal

Pancreatic enzyme prescription following ivacaftor licensing: A retrospective analysis of the US and UK cystic fibrosis registries

Authors : Calthorpe, Rebecca; Rosenfeld, Margaret; Goss, Christopher H

Subjects: Male; Adult; Registry

Source: Calthorpe, R, Rosenfeld, M, Goss, C H, Green, N, Derleth, M, Carr, S B, Smyth, A & Stewart, I 2024, ' Pancreatic enzyme prescription following ivacaftor licensing: A

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