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Subject : medicine.drug

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Characterization of Human Anti-Dengue NS1 Monoclonal Antibodies Derived from Patients Infected with DENV-2

Authors : Pongrama Ramasoota; Surachet Benjathummarak; Siriporn Kowaboot

Subjects: Microbiology (medical); Plasmin; medicine.drug_class

Source: Japanese Journal of Infectious Diseases. 75:24-30

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The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target

Authors : Maren de Vries; Fabrice Bailly; Philippe Cotelle

Subjects: Exonuclease; Ribonucleotide; viruses

Source: Cell Death and Differentiation

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Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2

Authors : Jessica Milia; Fabrizio Carletti; Nicole Grandi

Subjects: Microbiology (medical); Immunology; Virulence

Source: Virulence, Vol 12, Iss 1, Pp 1580-1596 (2021)Virulencearticle-version (VoR) Version of Record

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Linkage of resistance-associated substitutions in GT1 sofosbuvir + NS5A inhibitor failures treated with glecaprevir/pibrentasvir

Authors : Joy Peter; Larry Michael; Rakesh Tripathi

Subjects: Adult; Male; 0301 basic medicine

Source: Journal of Hepatology. 75:820-828

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Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry

Authors : De Lin; Charlotte J. Green; Alain-Pierre Petit

Subjects: 0301 basic medicine; Methyltransferase; viruses

Source: Slas Discovery

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Efficacy and safety of ravidasvir plus sofosbuvir in patients with chronic hepatitis C infection without cirrhosis or with compensated cirrhosis (STORM-C-1): interim analysis of a two-stage, open-label, multicentre, single arm, phase 2/3 trial

Authors : Sasikala Siva; Anchalee Avihingsanon; Nicole Ngo-Giang-Huong

Subjects: Adult; Liver Cirrhosis; Male

Source: The Lancet Gastroenterology & Hepatology. 6:448-458

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Coronavirus genomic nsp14‐ExoN, structure, role, mechanism, and potential application as a drug target

Authors : Mohammed Tahir

Subjects: RNA recombination; viruses; coronavirus

Source: Journal of Medical Virology

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Identification of doxorubicin as a potential therapeutic against SARS-CoV-2 (COVID-19) protease: a molecular docking and dynamics simulation studies

Authors : Varish Ahmad; Ali H. Alharbi; Qazi Mohammad Sajid Jamal

Subjects: Stereochemistry; In silico; medicine.medical_treatment

Source: Journal of Biomolecular Structure & Dynamicsarticle-version (VoR) Version of Record

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Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure

Authors : Smith, David A.; Fernandez-Antunez, Carlota; Magri, Andrea ...

Subjects: ns2; Sofosbuvir; [SDV]Life Sciences [q-bio]

Source: Nature CommunicationsNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)STOP-HCV Consortium 2021, ' Viral genome wide association study identifies novel

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Seraprevir and sofosbuvir for treatment of chronic hepatitis C virus infection: A single‐arm, open‐label, phase 3 trial

Authors : Yongning Xin; Guicheng Wu; Zhaowei Tong

Subjects: safety; Adult; Liver Cirrhosis

Source: Journal of Gastroenterology and Hepatology

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