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Academic Journal

Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice.

  • Authors : Caron NS; Centre for Molecular Medicine and Therapeutics, Vancouver, BC, V5Z 4H4, Canada.; BC Children's Hospital Research Institute, Vancouver, BC, V5Z 4H4, Canada.

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/genetics ; Huntington Disease*/Huntington Disease*/Huntington Disease*/blood ; Huntington Disease*/Huntington Disease*/Huntington Disease*/cerebrospinal fluid

  • Source: Translational neurodegeneration [Transl Neurodegener] 2024 Oct 08; Vol. 13 (1), pp. 50. Date of Electronic Publication: 2024 Oct 08.Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158

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Academic Journal

Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model.

  • Authors : Mohammed A; Department of Basic Medical Sciences, College of Medicine-Dar Al Uloom University, Riyadh, Saudi Arabia.; Department of Histology and Embryology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Subjects: Huntington Disease*/Huntington Disease*/Huntington Disease*/drug therapy ; Huntington Disease*/Huntington Disease*/Huntington Disease*/metabolism ; Luteolin*/Luteolin*/Luteolin*/pharmacology

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Sep; Vol. 30 (9), pp. e70025.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949

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Academic Journal

Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington’s disease mice and innervate the striatum

Subjects: Huntington's Disease; Technology; 1.1 Normal biological development and functioning

  • Source: Mol TherMolecular Therapy, vol 31, iss 12

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Academic Journal

Disruption of the mitochondrial network in a mouse model of Huntington's disease visualized by in-tissue multiscale 3D electron microscopy

Subjects: Male; Quantitative Biology - Subcellular Processes; FOS: Physical sciences

  • Source: Acta Neuropathol CommunDigital.CSIC. Repositorio Institucional del CSICConsejo Superior de Investigaciones Científicas (CSIC)Zaguán. Repositorio Digital de la Universidad de

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Academic Journal

TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration

Subjects: Proteomics; 0301 basic medicine; Multi-omics

  • Source: J NeuroinflammationJournal of Neuroinflammation, Vol 21, Iss 1, Pp 1-26 (2024)

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Academic Journal

Motor skill learning modulates striatal extracellular vesicles’ content in a mouse model of Huntington’s disease

Subjects: Proteomics; Male; 0301 basic medicine

  • Source: Cell Commun SignalAcademica-e. Repositorio Institucional de la Universidad Pública de NavarraUniversidad Pública de NavarraCell Communication and Signaling, Vol 22, Iss 1, Pp 1-16

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Academic Journal

Astrocytic contributions to Huntington's disease pathophysiology

Subjects: Neurons; glia; striatum

  • Source: Khakh, B S & Goldman, S A 2023, ' Astrocytic contributions to Huntington's disease pathophysiology ', Annals of the New York Academy of

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Academic Journal

Mutant Huntingtin Protein Interaction Map Implicates Dysregulation of Multiple Cellular Pathways in Neurodegeneration of Huntington’s Disease

Subjects: Huntington's Disease; Research Report; 0301 basic medicine

  • Source: J Huntingtons DisJournal of Huntington's Disease, vol 11, iss 3

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Academic Journal

Progressive Mitochondrial Dysfunction of Striatal Synapses in R6/2 Mouse Model of Huntington’s Disease

Subjects: 0303 health sciences; Huntington's disease; Oxygen consumption

  • Source: Journal of Huntington's Disease. 11:121-140

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Academic Journal

Diminished LC3-Associated Phagocytosis by Huntington’s Disease Striatal Astrocytes

Subjects: Huntington's Disease; Research Report; 0301 basic medicine

  • Source: J Huntingtons DisJournal of Huntington's Disease, vol 11, iss 1

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  • 1-10 of  1,033 results for ""Huntington's disease""