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14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains.

• Authors : Pohl P; Department of Structural Biology of Signaling Proteins, Division BIOCEV, Institute of Physiology of the Czech Academy of Sciences, Vestec, Czech Republic.; 2nd Faculty of Medicine, Charles University, Prague, Czech Republic.

Subjects: WW Domains*; 14-3-3 Proteins/14-3-3 Proteins/14-3-3 Proteins/*genetics ; Mice/Mice/Mice/*genetics

• Source: Communications biology [Commun Biol] 2021 Jul 22; Vol. 4 (1), pp. 899. Date of Electronic Publication: 2021 Jul 22.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Nedd4-1 regulates human sodium-dependent vitamin C transporter-2 functional expression in neuronal and epithelial cells

• Authors : Teafatiller, Trevor; Perez, Oasis; Kitazawa, Masashi

Subjects: Medical Physiology; Biomedical and Clinical Sciences; Acquired Cognitive Impairment

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The SGK3-triggered ubiquitin-proteasome degradation of podocalyxin (PC) and ezrin in podocytes was associated with the stability of the PC/ezrin complex.

• Authors : Yuan, Ya-Pei; Zhao, Hong; Peng, Li-Qin

Subjects: Animals; Cell Line; Transformed

• Source: Cell death & disease. 9(11)

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Loss of NEDD4 causes complete XY gonadal sex reversal in mice

• Authors : Windley, Simon P; Mayere, Chloé; McGovern, Alice E

Subjects: info:eu-repo/classification/ddc/576.5; XX Testicular Disorders of Sex Development; Animals46

• Source: ISSN: 2041-4889 ; Cell death and disease, vol. 13, no. 1 (2022) 75.

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Ubiquitin plays an atypical role in GPCR-induced p38 MAP kinase activation on endosomes

• Authors : Grimsey, Neil J; Aguilar, Berenice; Smith, Thomas H

Subjects: Biochemistry and Cell Biology; Biomedical and Clinical Sciences; Biological Sciences

• Source: Journal of Cell Biology. 210(7)

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mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity

• Authors : Gleason, Catherine E; Frindt, Gustavo; Cheng, Chih-Jen

Subjects: Medical Physiology; Biomedical and Clinical Sciences; Hypertension

• Source: Journal of Clinical Investigation. 125(1)

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The Antiproliferative Response of Indole-3-Carbinol in Human Melanoma Cells Is Triggered by an Interaction with NEDD4-1 and Disruption of Wild-Type PTEN Degradation

• Authors : Aronchik, Ida; Kundu, Aishwarya; Quirit, Jeanne G

Subjects: Biochemistry and Cell Biology; Biomedical and Clinical Sciences; Oncology and Carcinogenesis

• Source: Molecular Cancer Research. 12(11)

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The ubiquitin ligase NEDD4-2/NEDD4L regulates both sodium homeostasis and fibrotic signaling to prevent end-stage renal disease

• Authors : Manning, J.A.; Shah, S.S.; Nikolic, A.

Subjects: Animals; Mice; Transgenic

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Nedd4 is a specific E3 ubiquitin ligase for the NMDA receptor subunit GluN2D

• Authors : Gautam, Vivek; Trinidad, Jonathan C; Rimerman, Ronald A

Subjects: Pharmacology and Pharmaceutical Sciences; Biomedical and Clinical Sciences; Mental Health

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Scaffold Protein Connector Enhancer of Kinase Suppressor of Ras Isoform 3 (CNK3) Coordinates Assembly of a Multiprotein Epithelial Sodium Channel (ENaC)-regulatory Complex*

• Authors : Soundararajan, Rama; Ziera, Tim; Koo, Eric

Subjects: Medical Physiology; Biomedical and Clinical Sciences; Kidney Disease

• Source: Journal of Biological Chemistry. 287(39)

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