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Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis

Authors : Lucy Ellis; Yumi Park; Ola Epemolu

Subjects: 0301 basic medicine; Protein Conformation; 030106 microbiology

Source: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de MadridConsejería de Sanidad de la Comunidad de Madrid

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Identification and preliminary structure-activity relationship studies of novel pyridyl sulfonamides as potential Chagas disease therapeutic agents

Authors : Olivia Corcoran; Marcos Meuser Batista; Asma Inam Ullah

Subjects: Chagas disease; Cell Survival; Pyridines

Source: Bioorganicmedicinal chemistry letters. 28(11)

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Monoclonal antibodies with group specificity toward sulfonamides: selection of hapten and antibody selectivity

Authors : Wenxiao Jiang; Yajie Sheng; Zhanhui Wang

Subjects: Models, Molecular; medicine.drug_class; Stereochemistry

Source: Analytical and Bioanalytical Chemistry. 405:4027-4037

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Which Carbonic Anhydrases are Targeted by the Antiepileptic Sulfonamides and Sulfamates?

Authors : Claudiu T. Supuran; Giuseppina De Simone; Andrea Scozzafava

Subjects: Topiramate; medicine.medical_treatment; Carbonic anhydrase II

Source: Chemical Biology & Drug Design. 74:317-321

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Synthesis, Pharmacological Profile and Docking Studies of New Sulfonamides Designed as Phosphodiesterase-4 Inhibitors

Authors : Vinicius F. Carvalho; Lídia Moreira Lima; Suzana V.S. Cardozo

Subjects: 0301 basic medicine; Male; Pulmonology

Source: PLoS ONE, Vol 11, Iss 10, p e0162895 (2016)PLoS ONE

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Nitrotriazole- and imidazole-based amides and sulfonamides as antitubercular agents

Authors : Francisco Arrieta; Howard S. Rosenzweig; Alexander Arena

Subjects: Antitubercular Agents; Drug Evaluation, Preclinical; Drug resistance

Source: Antimicrobial agents and chemotherapy. 58(11)

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Synthesis and biological evaluation of substituted N-[3-(1H-pyrrol-1-yl)methyl]-1,2,5,6-tetrahydropyridin-1-yl]benzamide/benzene sulfonamides as anti-inflammatory agents

Authors : Madhavi, Gangapuram; Elizabeth, Mazzio; Suresh, Eyunni

Subjects: Lipopolysaccharides; Sulfonamides; Molecular Structure

Source: Archiv der Pharmazie. 347(5)

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Identification of a class of sulfonamides highly active against dihydropteroate synthase form Toxoplasma gondii, Pneumocystis carinii, and Mycobacterium avium

Authors : Mohamed Nasr; Li Chun Chio; Sherry F. Queener

Subjects: Sulfamethoxazole; Sulfadiazine; Microbiology

Source: Antimicrobial Agents and Chemotherapy. 40:727-733

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Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

Authors : Julie A. Tucker; Ben Acton; Ian D. Waddell

Subjects: 0301 basic medicine; Male; Models, Molecular

Source: Waszkowycz, B, Smith, K, Mcgonagle, A, Jordan, A, Acton, B, Fairweather, E, Griffiths, L, Hamilton, N M, Hamilton, N, Hitchin, J R, Hutton, C, James, D I, Jones, C D, Jones, S, Mould, D, Small, H F,

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Treatment of bubonic plague with sulfonamides and antibiotics

Authors : S S, SOKHEY; P M, WAGLE; M K, HABBU

Subjects: Sulfathiazoles; Plague; Sulfonamides

Source: Bulletin of the World Health Organization. 9(5)

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