Search Results

Oncolytic alphavirus-induced extracellular vesicles counteract the immunosuppressive effect of melanoma-derived extracellular vesicles

• Authors : Bhatt, Darshak K; Boerma, Annemarie; Bustos, Silvina Odete

Subjects: Extracellular Vesicles/metabolism; Melanoma/therapy; Oncolytic Viruses/physiology

• Source: Bhatt , D K , Boerma , A , Bustos , S O , Otake , A H , Murillo Carrasco , A G , Reis , P P , Chammas , R , Daemen , T & Andrade , L N D S 2025 , ' Oncolytic alphavirus-induced extracellular vesicles

Record details

Modeling NK-cell lymphoma in mice reveals its cell-of-origin and microenvironmental changes and identifies therapeutic targets.

• Authors : Koya, J.; Tanigawa, T.; Mizuno, K.

Subjects: Animals; Killer Cells; Natural/immunology

• Source: Nature communications, vol. 15, no. 1, pp. 9106

Record details

GSDMD is associated with survival in human breast cancer but does not impact anti-tumor immunity in a mouse breast cancer model.

• Authors : Boersma, B.; Puddinu, V.; Huard, A.

Subjects: Animals; Phosphate-Binding Proteins/metabolism; Phosphate-Binding Proteins/genetics

• Source: Frontiers in immunology, vol. 15, pp. 1396777

Record details

Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy.

• Authors : Wang, C.; Zeng, Q.; Gül, Z.M.

Subjects: Animals; Humans; Mice

• Source: Cell, vol. 187, no. 11, pp. 2690-2702.e17

Record details

IKKα-deficient lung adenocarcinomas generate an immunosuppressive microenvironment by overproducing Treg-inducing cytokines

• Authors : Na-Young Song; Xin Li; Buyong Ma

Subjects: Adenocarcinoma of Lung / immunology; Animals; CD4-Positive T-Lymphocytes / immunology

Record details

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion

• Authors : Gangoso, Ester; Southgate, Benjamin; Bradley, Leanne

Subjects: Animals; Apoptosis; Biomarkers

• Source: Gangoso , E , Southgate , B , Bradley , L , Rus , S , Galvez-Cancino , F , McGivern , N , Güç , E , Kapourani , C-A , Byron , A , Ferguson , K M , Alfazema , N , Morrison , G , Grant , V , Blin , C

Record details

Cystathionine-gamma-lyase overexpression in T cells enhances antitumor effect independently of cysteine autonomy.

• Authors : Lancien, M.; Gueno, L.; Salle, S.

Subjects: Adoptive Transfer/methods; Animals; CD8-Positive T-Lymphocytes/metabolism

• Source: Cancer science, vol. 112, no. 5, pp. 1723-1734

Record details

Interpretation of T cell states from single-cell transcriptomics data using reference atlases.

• Authors : Andreatta, M.; Corria-Osorio, J.; Müller, S.

Subjects: Animals; Cell Differentiation/immunology; Cohort Studies

• Source: Nature communications, vol. 12, no. 1, pp. 2965

Record details

Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors

• Authors : Kosti, Paris; Opzoomer, James W; Larios-Martinez, Karen I

Subjects: Animals; Cell Line; Tumor/metabolism

• Source: Kosti , P , Opzoomer , J W , Larios-Martinez , K I , Henley-Smith , R , Scudamore , C L , Okesola , M , Taher , M Y M , Davies , D M , Muliaditan , T , Larcombe-Young , D , Woodman , N , Gillett , C E

Record details

Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model

• Authors : Metzger, Philipp; Kirchleitner, Sabrina Viktoria; Boehmer, Daniel

Subjects: Immunosuppression [MeSH]; Myeloid-Derived Suppressor Cells/immunology [MeSH]; Pancreatic Neoplasms/pathology [MeSH]

• Source: http://lobid.org/resources/99370671253406441#!, 69(10):2101-2112.

Record details