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DRP1 regulates fatty acid oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics

• Authors : Axelrod, Christopher L.; King, William T.; Kirwan, John P.

Subjects: mitochondrial dynamics; DRP1

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Obesity Management in the Primary Prevention of Hepatocellular Carcinoma.

• Authors : Zunica, Elizabeth R. M.; Heintz, Elizabeth C.; Axelrod, Christopher L.

Subjects: OBESITY complications; OBESITY treatment; DISEASE progression

• Source: Cancers; Aug2022, Vol. 14 Issue 16, p4051, 18p

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Foregut Exclusion Enhances Incretin and Insulin Secretion After Roux-en-Y Gastric Bypass in Adults With Type 2 Diabetes.

• Authors : Kirwan, John P.; Axelrod, Christopher L.; Kullman, Emily L.

Subjects: INCRETINS; INSULIN; TYPE 2 diabetes

• Source: Journal of Clinical Endocrinology & Metabolism; Oct2021, Vol. 106 Issue 10, pe4192-e4201, 10p

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Roux-en-Y gastric bypass restores islet function and morphology independent of body weight in ZDF rats.

• Authors : Mosinski, J. David; Aminian, Ali; Axelrod, Christopher L.

Subjects: GASTRIC bypass; BODY weight; TYPE 2 diabetes

• Source: American Journal of Physiology: Endocrinology & Metabolism; Feb2021, Vol. 320 Issue 2, pE392-E398, 7p

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BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control.

• Authors : Axelrod, Christopher L; King, William T; Davuluri, Gangarao

• Source: EMBO Molecular Medicine; 7/7/2020, Vol. 12 Issue 7, p1-20, 20p

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Gastric Bypass Surgery Improves the Skeletal Muscle Ceramide/S1P Ratio and Upregulates the AMPK/ SIRT1/ PGC-1α Pathway in Zucker Diabetic Fatty Rats.

• Authors : Huang, Hazel; Axelrod, Christopher L.; Kirwan, John P.

Subjects: GASTRIC bypass; PGC-1 protein; SKELETAL muscle

• Source: Obesity Surgery; Jul2019, Vol. 29 Issue 7, p2158-2165, 8p

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Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD.

• Authors : HARI, ADITHYA¹; FEALY, CIARÀN E.²; AXELROD, CHRISTOPHER L.³

• Source: Medicine & Science in Sports & Exercise; Jul2020, Vol. 52 Issue 7, p1449-1455, 7p

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Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.

• Authors : King WT; Department of Translational Services, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.

Subjects: Calcium Signaling* ; Mitochondrial Dynamics*; Dynamins/Dynamins/Dynamins/*metabolism

• Source: The Journal of biological chemistry [J Biol Chem] 2021 Oct; Vol. 297 (4), pp. 101196. Date of Electronic Publication: 2021 Sep 13.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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β-Hydroxybutyrate is reduced in humans with obesity-related NAFLD and displays a dose-dependent effect on skeletal muscle mitochondrial respiration in vitro.

• Authors : Mey JT; Integrated Physiology and Molecular Medicine, Pennington Biomedical Research Center, Baton Rouge, Louisiana.; Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.

Subjects: 3-Hydroxybutyric Acid/3-Hydroxybutyric Acid/3-Hydroxybutyric Acid/*metabolism ; Liver/Liver/Liver/*metabolism ; Mitochondria, Muscle/Mitochondria, Muscle/Mitochondria, Muscle/*metabolism

• Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 Jul 01; Vol. 319 (1), pp. E187-E195. Date of Electronic Publication: 2020 May 12.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium:

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Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro-elongation phenotype.

• Authors : Axelrod CL; Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.; Integrated Physiology and Molecular Medicine Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana.

Subjects: Mitochondrial Dynamics*; Exercise/Exercise/Exercise/*physiology ; Mitochondria, Muscle/Mitochondria, Muscle/Mitochondria, Muscle/*physiology

• Source: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2019 Apr; Vol. 225 (4), pp. e13216. Date of Electronic Publication: 2018 Dec 01.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262545 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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