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  • 1-10 of  1,895 results for ""toll-like receptor 4""
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Academic Journal

Loss of RIP3 alleviates insulin resistance and inflammation in gestational diabetes mellitus mice via TLR4/MyD88/NF-κB signaling pathway.

  • Authors : He Y; Department of Pathology, Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou City, Zhejiang Province, 324000, China.; Zhu W

Subjects: Diabetes, Gestational*/Diabetes, Gestational*/Diabetes, Gestational*/metabolism ; Insulin Resistance* ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism

  • Source: BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2025 Feb 14; Vol. 25 (1), pp. 163. Date of Electronic Publication: 2025 Feb 14.Publisher: BioMed Central Country of Publication: England NLM ID: 100967799 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2393

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Academic Journal

Multiple low-dose radiation ameliorates type-2 diabetes mellitus via gut microbiota modulation to activate TLR4/MyD88/NF-κB pathway.

  • Authors : Qin L; NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun, Jilin, 130021, People's Republic of China.; Liu R

Subjects: Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/Gastrointestinal Microbiome*/radiation effects ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism

  • Source: BMC endocrine disorders [BMC Endocr Disord] 2025 Feb 07; Vol. 25 (1), pp. 32. Date of Electronic Publication: 2025 Feb 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101088676 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6823

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Academic Journal

Sodium butyrate attenuates microglia-mediated neuroinflammation by modulating the TLR4/MyD88/NF-κB pathway and microbiome-gut-brain axis in cardiac arrest mice.

  • Authors : Sun J; Department of Critical Care Medicine, Renmin Hospital of Wuhan University, No. 99 ZhangZhidong Road, Wuhan, 430060, Hubei, China.; Central Laboratory, Renmin Hospital of Wuhan University, Wuhan, 430060, China.

Subjects: Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/metabolism ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Microglia*/Microglia*/Microglia*/drug effects

  • Source: Molecular brain [Mol Brain] 2025 Feb 17; Vol. 18 (1), pp. 13. Date of Electronic Publication: 2025 Feb 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

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Academic Journal

Fecal microbiota transplantation attenuates Alzheimer's disease symptoms in APP/PS1 transgenic mice via inhibition of the TLR4-MyD88-NF-κB signaling pathway-mediated inflammation.

  • Authors : Li X; Wenzhou Key Laboratory of Sanitary Microbiology; School of Laboratory Medicine and Life Sciences

Subjects: Fecal Microbiota Transplantation*/Fecal Microbiota Transplantation*/Fecal Microbiota Transplantation*/methods ; Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/therapy

  • Source: Behavioral and brain functions : BBF [Behav Brain Funct] 2025 Jan 08; Vol. 21 (1), pp. 2. Date of Electronic Publication: 2025 Jan 08.Publisher: BioMed Central Country of Publication: England NLM ID: 101245751 Publication Model: Electronic Cited Medium: Internet ISSN: 1744-9081

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Academic Journal

Evaluation of the protective role of resveratrol on LPS-induced septic intestinal barrier function via TLR4/MyD88/NF-κB signaling pathways.

  • Authors : Shi Z; Department of Critical Care Medicine, Tongde Hospital of Zhejiang Province, #234 Gucui Road, Hangzhou, 310012, Zhejiang, People's Republic of China.; Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, 310012, Zhejiang, People's Republic of China.

Subjects: Resveratrol*/Resveratrol*/Resveratrol*/pharmacology ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Jan 04; Vol. 15 (1), pp. 828. Date of Electronic Publication: 2025 Jan 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel Inhibitory Actions of Neuroactive Steroid [3α,5α]-3-Hydroxypregnan-20-One on Toll-like Receptor 4-Dependent Neuroimmune Signaling.

  • Authors : Lopez AG; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Bowles Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, 3027 Thurston Bowles Bldg., CB 7178, Chapel Hill, NC 27599, USA.

Subjects: Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/antagonists & inhibitors ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: Biomolecules [Biomolecules] 2024 Nov 13; Vol. 14 (11). Date of Electronic Publication: 2024 Nov 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Acetylation of TIR domains in the TLR4-Mal-MyD88 complex regulates immune responses in sepsis.

  • Authors : Li X; Institute of Clinical Medicine Research, Zhejiang Provincial People's Hospital of Hangzhou Medical College, Hangzhou, China. .; Yantai Peninsular Cancer Center, Binzhou Medical University, Yantai, China. .

Subjects: Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/genetics ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/immunology

  • Source: The EMBO journal [EMBO J] 2024 Nov; Vol. 43 (21), pp. 4954-4983. Date of Electronic Publication: 2024 Sep 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

TACI Ig Fusion Protein Inhibits TLR4/MyD88/NF-κB Pathway Alleviates Renal Injury in IgA Nephropathy Rats.

  • Authors : Sun J; Department of Nephrology, Baotou Medical College, Baotou, China.; Cheng Y

Subjects: Glomerulonephritis, IGA*/Glomerulonephritis, IGA*/Glomerulonephritis, IGA*/drug therapy ; Glomerulonephritis, IGA*/Glomerulonephritis, IGA*/Glomerulonephritis, IGA*/pathology ; Glomerulonephritis, IGA*/Glomerulonephritis, IGA*/Glomerulonephritis, IGA*/metabolism

  • Source: Iranian journal of kidney diseases [Iran J Kidney Dis] 2024 Dec 19; Vol. 18 (6), pp. 326-336. Date of Electronic Publication: 2024 Dec 19.Publisher: Iranian Society of Nephrology Country of Publication: Iran NLM ID: 101316967 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.

  • Authors : Yang Q; Department of Endocrinology, The people's Hospital of Leshan, Leshan, 614000, Sichuan, China.; Department of Endocrinology, The Affiliated Hospital of Southwest Medical University, Taiping Street 25, Jiangyang District, Luzhou, 646000, Sichuan, China.

Subjects: Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/drug therapy ; Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/metabolism ; Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/Polycystic Ovary Syndrome*/pathology

  • Source: Scientific reports [Sci Rep] 2024 Dec 02; Vol. 14 (1), pp. 29848. Date of Electronic Publication: 2024 Dec 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Anti-Inflammatory Effects of Cordyceps Cs-HK1 Fungus Exopolysaccharide on Lipopolysaccharide-Stimulated Macrophages via the TLR4/MyD88/NF-κB Pathway.

  • Authors : Zhu YY; Research Institute for Future Food, Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hung Hom, Kowloon 999077, Hong Kong.; Dong YH

Subjects: Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/Myeloid Differentiation Factor 88*/metabolism ; Cordyceps*/Cordyceps*/Cordyceps*/chemistry

  • Source: Nutrients [Nutrients] 2024 Nov 14; Vol. 16 (22). Date of Electronic Publication: 2024 Nov 14.Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,895 results for ""toll-like receptor 4""