Authors : Bretherton RC; Department of Bioengineering, University of Washington, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.

Subjects: Cardiomyopathy, Dilated*/Cardiomyopathy, Dilated*/Cardiomyopathy, Dilated*/physiopathology ; Cardiomyopathy, Dilated*/Cardiomyopathy, Dilated*/Cardiomyopathy, Dilated*/genetics ; Cardiomyopathy, Dilated*/Cardiomyopathy, Dilated*/Cardiomyopathy, Dilated*/pathology

Source: Science (New York, N.Y.) [Science] 2025 Nov 06; Vol. 390 (6773), pp. eadv9157. Date of Electronic Publication: 2025 Nov 06.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure.

Authors : Ohnuki Y; Department of Physiology, Tsurumi University School of Dental Medicine, Yokohama, Japan.; Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, Yokohama, Japan.

Subjects: Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/metabolism ; Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/genetics ; Heart Failure*/Heart Failure*/Heart Failure*/metabolism

Source: PloS one [PLoS One] 2025 Jun 17; Vol. 20 (6), pp. e0325986. Date of Electronic Publication: 2025 Jun 17 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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A decline in renal function is associated with a reduction in myocardial mechano-energetic efficiency in individuals at high cardiometabolic risk.

Authors : Cefalo CMA; Department of Clinical and Molecular Medicine, University of Rome-Sapienza, 00189, Rome, Italy. .; Fiorentino TV

Subjects: Glomerular Filtration Rate* ; Ventricular Function, Left* ; Kidney*/Kidney*/Kidney*/physiopathology

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Aug 18; Vol. 24 (1), pp. 342. Date of Electronic Publication: 2025 Aug 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840

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Epicardial adipose tissue volume is associated with impaired left ventricular strain in patients with metabolic syndrome: the mediating role of myocardial energetic efficiency.

Authors : Yan WF; Department of Radiology, West China Hospital, Sichuan University, 37# Guo Xue Xiang, Chengdu, 610041, Sichuan, China.; Wang J

Subjects: Metabolic Syndrome*/Metabolic Syndrome*/Metabolic Syndrome*/physiopathology ; Metabolic Syndrome*/Metabolic Syndrome*/Metabolic Syndrome*/complications ; Metabolic Syndrome*/Metabolic Syndrome*/Metabolic Syndrome*/diagnosis

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Aug 09; Vol. 24 (1), pp. 325. Date of Electronic Publication: 2025 Aug 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840

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Myocardial composition and contractile function of right atrial trabeculae from type 2 diabetic and nondiabetic male patients.

Authors : Zhang LT; Department of Physiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Power AS

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/physiopathology ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/pathology

Source: Physiological reports [Physiol Rep] 2025 Aug; Vol. 13 (15), pp. e70509.Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM

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Hyperthermia Augments the H1-Histamine Receptor-Mediated Force in the Human Atrium.

Authors : Pham TH; Institute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Straße 4, D-06097 Halle (Saale), Germany.; Grundig P

Subjects: Heart Atria*/Heart Atria*/Heart Atria*/metabolism ; Heart Atria*/Heart Atria*/Heart Atria*/physiopathology ; Heart Atria*/Heart Atria*/Heart Atria*/drug effects

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 16; Vol. 26 (14). Date of Electronic Publication: 2025 Jul 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Human cardiac tissues produce lower contractile stress and exhibit slower cross-bridge cycling in type 2 diabetes.

Authors : Musgrave JH; Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand. .; Han JC

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Jul 03; Vol. 24 (1), pp. 266. Date of Electronic Publication: 2025 Jul 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840

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The adverse effects of metabolic disorder on left ventricular myocardial mechano-energetic efficiency and dysfunction in ischemic cardiomyopathy: insight from a cardiac MRI study.

Authors : Jiang L; Department of Radiology, West China Hospital, Sichuan University, 37# Guo Xue Xiang, Chengdu, 610041, Sichuan, China.; Li Y

Subjects: Ventricular Function, Left* ; Ventricular Dysfunction, Left*/Ventricular Dysfunction, Left*/Ventricular Dysfunction, Left*/physiopathology ; Ventricular Dysfunction, Left*/Ventricular Dysfunction, Left*/Ventricular Dysfunction, Left*/diagnostic imaging

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Jul 02; Vol. 24 (1), pp. 261. Date of Electronic Publication: 2025 Jul 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840

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The role of transient receptor potential melastatin channels in compressive force-induced contraction of primary cardiac pericytes.

Authors : Methner C; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, Oregon, USA.; Cilento E

Subjects: TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/metabolism ; TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/agonists ; TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/antagonists & inhibitors

Source: Physiological reports [Physiol Rep] 2025 Jun; Vol. 13 (12), pp. e70396.Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM

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The value of myocardial contraction fraction and long-axis strain to predict late gadolinium enhancement in multiple myeloma patients with secondary cardiac amyloidosis.

Authors : Hu M; Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1, Minde Road, Donghu District, Nanchang, Jiangxi, 330006, People's Republic of China.; Song Y

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/diagnostic imaging ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/complications ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/pathology

Source: Scientific reports [Sci Rep] 2024 Jul 22; Vol. 14 (1), pp. 16832. Date of Electronic Publication: 2024 Jul 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy.

Epac1 increases myosin regulatory light-chain phosphorylation, energetic cost of contraction, and susceptibility to heart failure.

A decline in renal function is associated with a reduction in myocardial mechano-energetic efficiency in individuals at high cardiometabolic risk.

Epicardial adipose tissue volume is associated with impaired left ventricular strain in patients with metabolic syndrome: the mediating role of myocardial energetic efficiency.

Myocardial composition and contractile function of right atrial trabeculae from type 2 diabetic and nondiabetic male patients.

Hyperthermia Augments the H1-Histamine Receptor-Mediated Force in the Human Atrium.

Human cardiac tissues produce lower contractile stress and exhibit slower cross-bridge cycling in type 2 diabetes.

The adverse effects of metabolic disorder on left ventricular myocardial mechano-energetic efficiency and dysfunction in ischemic cardiomyopathy: insight from a cardiac MRI study.

The role of transient receptor potential melastatin channels in compressive force-induced contraction of primary cardiac pericytes.

The value of myocardial contraction fraction and long-axis strain to predict late gadolinium enhancement in multiple myeloma patients with secondary cardiac amyloidosis.

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