Search Results

The proteostasis network provides targets for neurodegeneration.

• Authors : Newton TM; ALBORADA Drug Discovery Institute, University of Cambridge Island Research Building Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0AH, UK.; Reflection Therapeutics, IdeaSpace, University of Cambridge Biomedical Innovation Hub, Cambridge, UK.

Subjects: Heat-Shock Proteins/Heat-Shock Proteins/Heat-Shock Proteins/*metabolism ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*metabolism; Animals

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Sep; Vol. 176 (18), pp. 3508-3514. Date of Electronic Publication: 2019 May 23.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Functional Modules of the Proteostasis Network

• Authors : Jayaraj GG; Hipp MS; Hartl FU

Subjects: 0301 basic medicine; Protein Denaturation; Protein Folding

• Source: Cold Spring Harbor Perspectives in BiologyCold Spring Harbor perspectives in biology

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Particulate Air Pollutants Exacerbate Polyglutamine Aggregation in C. elegans

• Authors : Dagnachew, Mesgana; Green, Emily; Kikis, Elise

Subjects: Scholarship Sewanee 2020; Proteostasis network; Nano-particulate matter

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Underlying mechanisms and chemical/biochemical therapeutic approaches to ameliorate protein misfolding neurodegenerative diseases.

• Authors : Hekmatimoghaddam S; Department of Laboratory Sciences, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.; Zare-Khormizi MR

Subjects: Amyloidogenic Proteins/Amyloidogenic Proteins/Amyloidogenic Proteins/*antagonists & inhibitors ; Molecular Chaperones/Molecular Chaperones/Molecular Chaperones/*metabolism ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*drug therapy

• Source: BioFactors (Oxford, England) [Biofactors] 2017 Nov; Vol. 43 (6), pp. 737-759. Date of Electronic Publication: 2016 Feb 22.Publisher: Ios Press Country of Publication: Netherlands NLM ID: 8807441 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Nanoparticulate air pollution disrupts proteostasis in Caenorhabditis elegans.

• Authors : Garcia Manriquez BA; Biology Department, The University of the South, Sewanee, TN, United States of America.; Papapanagiotou JA

Subjects: Air Pollution*/Air Pollution*/Air Pollution*/adverse effects ; Alzheimer Disease* ; Neurodegenerative Diseases*/Neurodegenerative Diseases*/Neurodegenerative Diseases*/metabolism

• Source: PloS one [PLoS One] 2023 Feb 23; Vol. 18 (2), pp. e0275137. Date of Electronic Publication: 2023 Feb 23 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Targeting Chaperone/Co-Chaperone Interactions with Small Molecules: A Novel Approach to Tackle Neurodegenerative Diseases.

• Authors : Wang L; Department of Neuroscience Care and Society, Division of Neurogeriatrics, Karolinska Institutet, 17164 Solna, Sweden.; Bergkvist L

Subjects: Molecular Chaperones/Molecular Chaperones/Molecular Chaperones/*metabolism ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*genetics; Humans

• Source: Cells [Cells] 2021 Sep 29; Vol. 10 (10). Date of Electronic Publication: 2021 Sep 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Proteostasis Disturbances and Inflammation in Neurodegenerative Diseases.

• Authors : Sonninen TM; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Neulaniementie 2, 70211 Kuopio, Finland.; Goldsteins G

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*genetics ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*genetics ; Parkinson Disease/Parkinson Disease/Parkinson Disease/*genetics

• Source: Cells [Cells] 2020 Sep 28; Vol. 9 (10). Date of Electronic Publication: 2020 Sep 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Proteostasis and Proteotoxicity in the Network Medicine Era.

• Authors : Lualdi M; Department of Science and High Technology and Center of Bioinformatics, University of Insubria, I-21052 Busto Arsizio, Italy.; Alberio T

Subjects: Proteostasis*; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*pathology ; Protein Aggregation, Pathological/Protein Aggregation, Pathological/Protein Aggregation, Pathological/*complications

• Source: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 03; Vol. 21 (17). Date of Electronic Publication: 2020 Sep 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases.

• Authors : Bhore N; Taiwan International Graduate Program in Interdisciplinary Neuroscience, National Yang-Ming University and Academia Sinica, Taipei 11529, Taiwan. .; Institute of Cellular and Organismic Biology, Academia Sinica, Taipei 11529, Taiwan. .

Subjects: Dual-Specificity Phosphatases/Dual-Specificity Phosphatases/Dual-Specificity Phosphatases/*physiology ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*metabolism ; Proteostasis/Proteostasis/Proteostasis/*physiology

• Source: International journal of molecular sciences [Int J Mol Sci] 2017 Sep 13; Vol. 18 (9). Date of Electronic Publication: 2017 Sep 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Endoplasmic reticulum proteostasis impairment in aging.

• Authors : Martínez G; Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.; Biomedical Neuroscience Institute, Faculty of Medicine, University of Chile, Santiago, Chile.

Subjects: Aging/Aging/Aging/*drug effects ; Endoplasmic Reticulum Stress/Endoplasmic Reticulum Stress/Endoplasmic Reticulum Stress/*drug effects ; Neurodegenerative Diseases/Neurodegenerative Diseases/Neurodegenerative Diseases/*prevention & control

• Source: Aging cell [Aging Cell] 2017 Aug; Vol. 16 (4), pp. 615-623. Date of Electronic Publication: 2017 Apr 23.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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