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Molecular determinants of μ-conotoxin KIIIA interaction with the human voltage-gated sodium channel NaV1.7

Authors : Vladimir Yarov-Yarovoy; Phuong T. Nguyen; Ian H. Kimball

Subjects: chemistry.chemical_classification; Pharmacology; 0303 health sciences

Source: Frontiers in Pharmacology. 14

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Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation

Authors : Naazneen Sofeo; Dirk C. Winkelman; Karina Leung

Subjects: 0303 health sciences; Combination therapy; business.industry

Source: Frontiers in Molecular Biosciences. 10

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Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death

Authors : Christer S. Ejsing; Sandra F Gallego; Anthony H. Futerman

Subjects: Oligonucleotides, Antisense/genetics; Research & Experimental Medicine; Proteomics

Source: Mol TherSchmidt, S, Gallego, S F, Zelnik, I D, Kovalchuk, S, Albæk, N, Sprenger, R R, Øverup, C, Pewzner-Jung, Y, Futerman, A H, Lindholm, M W, Jensen, O N & Ejsing, C S 2022, ' Silencing of

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First insights into the honey bee (Apis mellifera) brain lipidome and its neonicotinoid-induced alterations associated with reduced self-grooming behavior

Authors : Paul H. Goodwin; Nuria Morfin; Thu Huong Pham

Subjects: 2. Zero hunger; 0303 health sciences; Multidisciplinary

Source: Journal of Advanced Research. 37:75-89

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Potency of olorofim (F901318) compared to contemporary antifungal agents against clinical Aspergillus fumigatus isolates, and review of azole resistance phenotype and genotype epidemiology in China

Authors : Min Zhu; Tobias Engel; Qiangqiang Zhang

Subjects: Drug; China; media_common.quotation_subject

Source: Antimicrobial Agents and Chemotherapy, 65, 5Antimicrobial Agents and ChemotherapyAntimicrobial Agents and Chemotherapy, 65

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The endocytic recycling compartment serves as a viral factory for hepatitis E virus

Authors : Cyrine Bentaleb; Kévin Hervouet; Claire Montpellier ...

Subjects: medicine.drug_class; viruses; Viral factories

Source: Cellular and Molecular Life SciencesCellular and Molecular Life Sciences, 2022, 79 (12), pp.615. ⟨10.1007/s00018-022-04646-y⟩

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The gut microbial metabolite, 3,4-dihydroxyphenylpropionic acid, alleviates hepatic ischemia/reperfusion injury via mitigation of macrophage pro-inflammatory activity in mice

Authors : Li Xie; Chenyang Huang; Peng Chen

Subjects: Hepatic ischemia/reperfusion injury; Metabolite; Ischemia

Source: Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 182-196 (2022)

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Clinical trials of resveratrol efficacy and safety

Authors : Veljko Ćućuz; Jelena Cvejić; Ljiljana Gojkovic-Bukarica

Subjects: 0303 health sciences; business.industry; review

Source: Vojnosanitetski pregled (2022) 79(6):613-618

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DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS‒STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis

Authors : Yanhong Gu; Jianhua Gao; Yang Sun

Subjects: DNA damage; Andrographolide; RM1-950

Source: Acta Pharmaceutica Sinica. BActa Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 262-273 (2022)

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Comprehensive transcriptome-wide analysis of spliceopathy correction of myotonic dystrophy using CRISPR-Cas9 in iPSCs-derived cardiomyocytes

Authors : Kshitiz Singh; Denis Furling; Sumitava Dastidar ...

Subjects: Candidate gene; TNNT2; Research & Experimental Medicine

Source: Molecular TherapyMolecular Therapy, Cell Press, 2021, 29 (11), ⟨10.1016/j.ymthe.2021.08.004⟩Molecular Therapy, 2021, 29 (11), ⟨10.1016/j.ymthe.2021.08.004⟩

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