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Academic Journal

CircPDE5A-encoded novel regulator of the PI3K/AKT pathway inhibits esophageal squamous cell carcinoma progression by promoting USP14-mediated de-ubiquitination of PIK3IP1.

  • Authors : Lei K; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.; Department of Thoracic Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.

Subjects: Esophageal Neoplasms*/Esophageal Neoplasms*/Esophageal Neoplasms*/metabolism ; Esophageal Neoplasms*/Esophageal Neoplasms*/Esophageal Neoplasms*/pathology ; Esophageal Neoplasms*/Esophageal Neoplasms*/Esophageal Neoplasms*/genetics

  • Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Apr 24; Vol. 43 (1), pp. 124. Date of Electronic Publication: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Academic Journal

PI3K/Akt signaling pathway mediates the effect of low-dose boron on barrier function, proliferation and apoptosis in rat intestinal epithelial cells.

  • Authors : Chen S; College of Animal Science, Anhui Science and Technology University, No. 9, Donghua Road, Fengyang County, Chuzhou City, Anhui Province, China.; Huang J

Subjects: Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism ; Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism; Rats

  • Source: Scientific reports [Sci Rep] 2024 Jan 03; Vol. 14 (1), pp. 393. Date of Electronic Publication: 2024 Jan 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

OBHS Drives Abnormal Glycometabolis Reprogramming via GLUT1 in Breast Cancer.

  • Authors : Wang K; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Bayi Road, Wuhan 430072, China.; Li Q

Subjects: Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 12; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

HO-1 mediated by PI3K/Akt/Nrf2 signaling pathway is involved in (-)-epigallocatechin-3-gallate-rescueing impaired cognitive function induced by chronic cerebral hypoperfusion in rat model.

  • Authors : Deng Y; Department of Geratology, Chongqing Mental Health Center, Chongqing, China.; Zhang X

Subjects: Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism ; Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/pharmacology ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: Experimental aging research [Exp Aging Res] 2022 Oct-Dec; Vol. 48 (5), pp. 428-443. Date of Electronic Publication: 2022 Jan 04.Publisher: Routledge Country of Publication: United States NLM ID: 7603335 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ginsenoside compound K inhibits the proliferation, migration and invasion of Eca109 cell via VEGF-A/Pi3k/Akt pathway.

  • Authors : Huang J; Department of Pharmacy, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China.; Pan D

Subjects: Esophageal Neoplasms*/Esophageal Neoplasms*/Esophageal Neoplasms*/genetics ; Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/genetics ; Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/Phosphatidylinositol 3-Kinases*/metabolism

  • Source: Journal of cardiothoracic surgery [J Cardiothorac Surg] 2022 May 03; Vol. 17 (1), pp. 99. Date of Electronic Publication: 2022 May 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101265113 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-8090

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Academic Journal

3-O-trans-caffeoyloleanolic acid improves acute lung injury via anti-inflammation and antioxidative stress-involved PI3K/AKT pathway.

  • Authors : Huang J; Department of Respiratory and Critical Care Medicine, Jiangxi Chest (Third people) Hospital, Nanchang, China.; Nong X

Subjects: Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*drug therapy ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*chemistry ; Oleanolic Acid/Oleanolic Acid/Oleanolic Acid/*analogs & derivatives

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2021 Jul; Vol. 98 (1), pp. 114-126. Date of Electronic Publication: 2021 May 19.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mangiferin inhibits cell migration and angiogenesis via PI3K/AKT/mTOR signaling in high glucose‑ and hypoxia‑induced RRCECs.

  • Authors : Shi J; Department of Ophthalmology, The People's Hospital of Deyang City, Deyang, Sichuan 618000, P.R. China.; Lv H

Subjects: Cell Hypoxia* ; Neovascularization, Physiologic*; Endothelial Cells/Endothelial Cells/Endothelial Cells/*metabolism

  • Source: Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Apr 26.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

EGFR-rich extracellular vesicles derived from highly metastatic nasopharyngeal carcinoma cells accelerate tumour metastasis through PI3K/AKT pathway-suppressed ROS.

  • Authors : Li F; State Key Laboratory of Biocontrol School of Life Sciences Sun Yat-sen University Guangzhou China.; Zhao X

Subjects: Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/pathology ; Nasopharyngeal Carcinoma*/Nasopharyngeal Carcinoma*/Nasopharyngeal Carcinoma*/blood

  • Source: Journal of extracellular vesicles [J Extracell Vesicles] 2020 Oct; Vol. 10 (1), pp. e12003. Date of Electronic Publication: 2020 Oct 30.Publisher: Wiley Country of Publication: United States NLM ID: 101610479 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2001-3078

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Academic Journal

Roles of transforming growth factor-β and phosphatidylinositol 3-kinase isoforms in integrin β1-mediated bio-behaviors of mouse lung telocytes.

  • Authors : Song D; Zhongshan Hospital Institute for Clinical Science, Shanghai Institute of Clinical Bioinformatics, Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases, Shanghai Medical College, Fudan University, Shanghai, China.; Tang L

Subjects: Integrin beta1/Integrin beta1/Integrin beta1/*metabolism ; Lung/Lung/Lung/*cytology ; Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/*metabolism

  • Source: Journal of translational medicine [J Transl Med] 2019 Dec 30; Vol. 17 (1), pp. 431. Date of Electronic Publication: 2019 Dec 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Academic Journal

Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor.

  • Authors : Li XX; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong.; Zhang SJ

Subjects: Coumarins/Coumarins/Coumarins/*pharmacology ; Nerve Sheath Neoplasms/Nerve Sheath Neoplasms/Nerve Sheath Neoplasms/*metabolism ; Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/Phosphatidylinositol 3-Kinases/*metabolism

  • Source: Cancer medicine [Cancer Med] 2018 Sep; Vol. 7 (9), pp. 4791-4800. Date of Electronic Publication: 2018 Aug 15.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  17 results for ""Huang J""