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  • 1-10 of  83 results for ""Nucleotides, Cyclic""
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Academic Journal

T Cell-Derived Apoptotic Extracellular Vesicles Hydrolyze cGAMP to Alleviate Radiation Enteritis via Surface Enzyme ENPP1.

  • Authors : Zhou Y; College of Life Sciences, Northwest University, Xi'an, Shaanxi, 710069, China.; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Center for Tissue Engineering, School of Stomatology, The Fourth Military Medical University, Xi'an, Shaanxi, 710032, China.

Subjects: Phosphoric Diester Hydrolases*/Phosphoric Diester Hydrolases*/Phosphoric Diester Hydrolases*/metabolism ; Extracellular Vesicles*/Extracellular Vesicles*/Extracellular Vesicles*/metabolism ; Enteritis*/Enteritis*/Enteritis*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Aug; Vol. 11 (31), pp. e2401634. Date of Electronic Publication: 2024 Jun 18.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression.

  • Authors : Baird JR; Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan St, Portland, OR, 97213, USA.; Alice AF

Subjects: Phosphoric Diester Hydrolases*/Phosphoric Diester Hydrolases*/Phosphoric Diester Hydrolases*/metabolism ; Pyrophosphatases*/Pyrophosphatases*/Pyrophosphatases*/metabolism ; Pyrophosphatases*/Pyrophosphatases*/Pyrophosphatases*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Dec 02; Vol. 14 (1), pp. 29913. Date of Electronic Publication: 2024 Dec 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tumor Exosomal ENPP1 Hydrolyzes cGAMP to Inhibit cGAS-STING Signaling.

  • Authors : An Y; Department of Pathology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, P. R. China.; Zhu J

Subjects: Exosomes*/Exosomes*/Exosomes*/metabolism ; Exosomes*/Exosomes*/Exosomes*/genetics ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 May; Vol. 11 (20), pp. e2308131. Date of Electronic Publication: 2024 Mar 18.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Structures of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL: identification of a novel conformational switch and its implication.

  • Authors : Yadav M; Crystallography and Molecular Biology Division, Saha Institute of Nuclear Physics, HBNI, 1/AF Bidhan Nagar, Kolkata 700064, India.; Pal K

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*chemistry ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Cyclic GMP/Cyclic GMP/Cyclic GMP/*analogs & derivatives

  • Source: The Biochemical journal [Biochem J] 2019 Nov 15; Vol. 476 (21), pp. 3333-3353.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Modulation of Compartmentalised Cyclic Nucleotide Signalling via Local Inhibition of Phosphodiesterase Activity.

  • Authors : Brescia M; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3TP, UK. .; Zaccolo M

Subjects: Nucleotides, Cyclic/Nucleotides, Cyclic/Nucleotides, Cyclic/*metabolism ; Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/Phosphodiesterase Inhibitors/*metabolism ; Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2016 Oct 02; Vol. 17 (10). Date of Electronic Publication: 2016 Oct 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Advances, Perspectives and Potential Engineering Strategies of Light-Gated Phosphodiesterases for Optogenetic Applications.

  • Authors : Tian Y; Department of Neurophysiology, Physiological Institute, University of Wuerzburg, 97070 Wuerzburg, Germany.; Yang S

Subjects: Optogenetics/Optogenetics/Optogenetics/*methods ; Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/*metabolism ; Protein Engineering/Protein Engineering/Protein Engineering/*methods

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 13; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cyclic nucleotide signalling compartmentation by PDEs in cultured vascular smooth muscle cells.

  • Authors : Zhang L; UMR-S 1180, INSERM, Univ Paris-Sud, Université Paris-Saclay, Châtenay-Malabry, France.; Bouadjel K

Subjects: Myocytes, Smooth Muscle/Myocytes, Smooth Muscle/Myocytes, Smooth Muscle/*metabolism ; Nucleotides, Cyclic/Nucleotides, Cyclic/Nucleotides, Cyclic/*metabolism ; Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/*metabolism

  • Source: British journal of pharmacology [Br J Pharmacol] 2019 Jun; Vol. 176 (11), pp. 1780-1792. Date of Electronic Publication: 2019 Apr 24.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Academic Journal

The Characterization of Escherichia coli CpdB as a Recombinant Protein Reveals that, besides Having the Expected 3´-Nucleotidase and 2´,3´-Cyclic Mononucleotide Phosphodiesterase Activities, It Is Also Active as Cyclic Dinucleotide Phosphodiesterase.

  • Authors : López-Villamizar I; Grupo de Enzimología, Departamento de Bioquímica y Biología Molecular y Genética, Facultad de Medicina, Universidad de Extremadura, Badajoz, Spain.; Cabezas A

Subjects: 2',3'-Cyclic-Nucleotide Phosphodiesterases/2',3'-Cyclic-Nucleotide Phosphodiesterases/2',3'-Cyclic-Nucleotide Phosphodiesterases/*metabolism ; Escherichia coli/Escherichia coli/Escherichia coli/*metabolism ; Escherichia coli Proteins/Escherichia coli Proteins/Escherichia coli Proteins/*metabolism

  • Source: PloS one [PLoS One] 2016 Jun 13; Vol. 11 (6), pp. e0157308. Date of Electronic Publication: 2016 Jun 13 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Gene cloning, expression, and characterization of a cyclic nucleotide phosphodiesterase from Arthrobacter sp. CGMCC 3584.

  • Authors : Zheng Z; College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing, 210009, People's Republic of China.; Zhu M

Subjects: Arthrobacter/Arthrobacter/Arthrobacter/*enzymology ; Nucleotides, Cyclic/Nucleotides, Cyclic/Nucleotides, Cyclic/*metabolism ; Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/Phosphoric Diester Hydrolases/*metabolism

  • Source: Applied biochemistry and biotechnology [Appl Biochem Biotechnol] 2013 Apr; Vol. 169 (8), pp. 2442-56. Date of Electronic Publication: 2013 Mar 02.Publisher: Humana Press Country of Publication: United States NLM ID: 8208561 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mechanisms of cyclic nucleotide phosphodiesterases in modulating T cell responses in murine graft-versus-host disease.

  • Authors : Weber M; Institute for Immunology, Johannes Gutenberg-University Medical Center, Mainz, Germany.; Lupp C

Subjects: Graft vs Host Disease/Graft vs Host Disease/Graft vs Host Disease/*enzymology ; Graft vs Host Disease/Graft vs Host Disease/Graft vs Host Disease/*immunology ; Nucleotides, Cyclic/Nucleotides, Cyclic/Nucleotides, Cyclic/*metabolism

  • Source: PloS one [PLoS One] 2013; Vol. 8 (3), pp. e58110. Date of Electronic Publication: 2013 Mar 06.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  83 results for ""Nucleotides, Cyclic""