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Academic Journal

VAPA mediates lipid exchange between Leishmania amazonensis and host macrophages.

Authors : Gdovinova I; INRS- Centre Armand-Frappier Santé Biotechnologie, Laval, Québec, Canada.; Infectiopôle INRS, Laval, Québec, Canada.

Subjects: Macrophages*/Macrophages*/Macrophages*/parasitology ; Macrophages*/Macrophages*/Macrophages*/metabolism ; Leishmania mexicana*/Leishmania mexicana*/Leishmania mexicana*/metabolism

Source: PLoS pathogens [PLoS Pathog] 2025 Mar 31; Vol. 21 (3), pp. e1012636. Date of Electronic Publication: 2025 Mar 31 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from Leishmania mexicana with Biological Activity against Promastigotes and Amastigotes.

Authors : Betancourt-Conde I; Facultad de Medicina y Nutrición, Universidad Juárez del Estado de Durango, Av. Universidad y Fanny Anitúa S/N, Durango 34000, Mexico.; Avitia-Domínguez C

Subjects: Antiprotozoal Agents/Antiprotozoal Agents/Antiprotozoal Agents/*pharmacology ; Arginase/Arginase/Arginase/*antagonists & inhibitors ; Benzimidazoles/Benzimidazoles/Benzimidazoles/*pharmacology

Source: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 19; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Catalase impairs Leishmania mexicana development and virulence.

Authors : Sádlová J; Department of Parasitology, Faculty of Science, Charles University, Prague, Czech Republic.; Podešvová L

Subjects: Catalase/Catalase/Catalase/*genetics ; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*growth & development ; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*pathogenicity

Source: Virulence [Virulence] 2021 Dec; Vol. 12 (1), pp. 852-867.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Micro-CT visualization of a promastigote secretory gel (PSG) and parasite plug in the digestive tract of the sand fly Lutzomyia longipalpis infected with Leishmania mexicana.

Authors : Hall MJR; Natural History Museum, London, United Kingdom.; Ghosh D

Subjects: Insect Vectors/Insect Vectors/Insect Vectors/*anatomy & histology ; Insect Vectors/Insect Vectors/Insect Vectors/*parasitology ; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*physiology

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Aug 27; Vol. 15 (8), pp. e0009682. Date of Electronic Publication: 2021 Aug 27 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Ku80 is involved in telomere maintenance but dispensable for genomic stability in Leishmania mexicana.

Authors : Poláková E; Life Science Research Centre, Faculty of Science, University of Ostrava, Ostrava, Czech Republic.; Albanaz ATS

Subjects: Genomic Instability*; Ku Autoantigen/Ku Autoantigen/Ku Autoantigen/*metabolism ; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*genetics

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Dec 29; Vol. 15 (12), pp. e0010041. Date of Electronic Publication: 2021 Dec 29 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Effect of Prophylactic Vaccination with the Membrane-Bound Acid Phosphatase Gene of Leishmania mexicana in the Murine Model of Localized Cutaneous Leishmaniasis.

Authors : Burgos-Reyes MA; Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México City, Mexico.; Baylón-Pacheco L

Subjects: Acid Phosphatase/Acid Phosphatase/Acid Phosphatase/*genetics ; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*physiology ; Leishmaniasis Vaccines/Leishmaniasis Vaccines/Leishmaniasis Vaccines/*immunology

Source: Journal of immunology research [J Immunol Res] 2021 Apr 09; Vol. 2021, pp. 6624246. Date of Electronic Publication: 2021 Apr 09 (Print Publication: 2021).Publisher: Wiley Country of Publication: Egypt NLM ID: 101627166 Publication Model: eCollection Cited Medium: Internet ISSN: 2314-7156

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Academic Journal

A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in Leishmania mexicana parasites during starvation.

Authors : Kalesh K; Department of Chemistry, Durham University, Durham, United Kingdom.; Denny PW

Subjects: Adaptation, Physiological* ; Starvation*; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*chemistry

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Dec 19; Vol. 13 (12), pp. e0007651. Date of Electronic Publication: 2019 Dec 19 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

Authors : Scala A; Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università di Messina, Messina, Italy.; Rescifina A

Subjects: Cysteine Proteases/Cysteine Proteases/Cysteine Proteases/*metabolism ; Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/*chemistry ; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*enzymology

Source: Chemical biology & drug design [Chem Biol Drug Des] 2018 Feb; Vol. 91 (2), pp. 597-604. Date of Electronic Publication: 2017 Nov 10.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A putative ATP/GTP binding protein affects Leishmania mexicana growth in insect vectors and vertebrate hosts.

Authors : Ishemgulova A; Life Science Research Centre, Faculty of Science, University of Ostrava, Ostrava, Czech Republic.; Biology Centre, Institute of Parasitology, Czech Academy of Sciences, České Budejovice (Budweis), Czech Republic.

Subjects: GTP-Binding Proteins/GTP-Binding Proteins/GTP-Binding Proteins/*metabolism ; Leishmania mexicana/Leishmania mexicana/Leishmania mexicana/*pathogenicity ; Macrophages/Macrophages/Macrophages/*parasitology

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2017 Jul 24; Vol. 11 (7), pp. e0005782. Date of Electronic Publication: 2017 Jul 24 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.

Authors : De Luca L; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.; Ferro S

Subjects: Benzimidazoles/Benzimidazoles/Benzimidazoles/*chemistry ; Cysteine Proteases/Cysteine Proteases/Cysteine Proteases/*metabolism ; Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/Cysteine Proteinase Inhibitors/*chemistry

Source: Chemical biology & drug design [Chem Biol Drug Des] 2018 Sep; Vol. 92 (3), pp. 1585-1596. Date of Electronic Publication: 2018 May 31.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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VAPA mediates lipid exchange between Leishmania amazonensis and host macrophages.

Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from Leishmania mexicana with Biological Activity against Promastigotes and Amastigotes.

Catalase impairs Leishmania mexicana development and virulence.

Micro-CT visualization of a promastigote secretory gel (PSG) and parasite plug in the digestive tract of the sand fly Lutzomyia longipalpis infected with Leishmania mexicana.

Ku80 is involved in telomere maintenance but dispensable for genomic stability in Leishmania mexicana.

Effect of Prophylactic Vaccination with the Membrane-Bound Acid Phosphatase Gene of Leishmania mexicana in the Murine Model of Localized Cutaneous Leishmaniasis.

A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in Leishmania mexicana parasites during starvation.

Ensemble-based ADME-Tox profiling and virtual screening for the discovery of new inhibitors of the Leishmania mexicana cysteine protease CPB2.8ΔCTE.

A putative ATP/GTP binding protein affects Leishmania mexicana growth in insect vectors and vertebrate hosts.

Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.

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