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Academic Journal

SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling.

  • Authors : Perico L; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy. .; Morigi M

Subjects: Spike Glycoprotein, Coronavirus* ; Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/cytology ; Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/virology

  • Source: Scientific reports [Sci Rep] 2023 Jul 14; Vol. 13 (1), pp. 11392. Date of Electronic Publication: 2023 Jul 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Potential Role of Complement System in the Progression of Ovarian Clear Cell Carcinoma Inferred from the Gene Ontology-Based Immunofunctionome Analysis.

  • Authors : Su KM; Department of Obstetrics and Gynecology, Tri-service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.

Subjects: Adenocarcinoma, Clear Cell/Adenocarcinoma, Clear Cell/Adenocarcinoma, Clear Cell/*genetics ; Complement C3a/Complement C3a/Complement C3a/*genetics ; Gene Expression Profiling/Gene Expression Profiling/Gene Expression Profiling/*methods

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 17; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

C3a and Its Receptor C3aR Are Detectable in Normal Human Epidermal Keratinocytes and Are Differentially Regulated via TLR3 and LL37.

  • Authors : Mommert S; Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany, .; Doenni L

Subjects: Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*metabolism ; Complement C3a/Complement C3a/Complement C3a/*metabolism ; Epidermal Cells/Epidermal Cells/Epidermal Cells/*immunology

  • Source: Journal of innate immunity [J Innate Immun] 2021; Vol. 13 (3), pp. 164-178. Date of Electronic Publication: 2021 Jan 14.Publisher: Karger Country of Publication: Switzerland NLM ID: 101469471 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Sustained activation of C3aR in a human podocyte line impairs the morphological maturation of the cells.

  • Authors : Zheng JM; Department of Nephrology, Taizhou Hospital, Wenzhou Medical University, Linhai, Zhejiang 317000, P.R. China.; Wang SS

Subjects: Podocytes/Podocytes/Podocytes/*metabolism ; Receptors, Complement/Receptors, Complement/Receptors, Complement/*metabolism; Arginine/Arginine/Arginine/analogs & derivatives

  • Source: Molecular medicine reports [Mol Med Rep] 2020 Dec; Vol. 22 (6), pp. 5326-5338. Date of Electronic Publication: 2020 Oct 22.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Role of complement 3a in the growth of mesangial cells from stroke-prone spontaneously hypertensive rats.

  • Authors : Ikeda K; Division of Nephrology, Hypertension and Endocrinology, Department of Medicine, Nihon University School of Medicine , Tokyo , Japan .; Fukuda N

Subjects: Complement C3a/Complement C3a/Complement C3a/*metabolism ; Hypertension/Hypertension/Hypertension/*metabolism ; Mesangial Cells/Mesangial Cells/Mesangial Cells/*metabolism

  • Source: Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2014; Vol. 36 (1), pp. 58-63. Date of Electronic Publication: 2013 May 28.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9305929 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Complement inhibition promotes endogenous neurogenesis and sustained anti-inflammatory neuroprotection following reperfused stroke.

  • Authors : Ducruet AF; Department of Neurological Surgery, Columbia University, New York, New York, United States of America. ; Zacharia BE

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*pharmacology ; Complement C3a/Complement C3a/Complement C3a/*antagonists & inhibitors ; Inflammation/Inflammation/Inflammation/*prevention & control

  • Source: PloS one [PLoS One] 2012; Vol. 7 (6), pp. e38664. Date of Electronic Publication: 2012 Jun 26.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Complement: a novel factor in basal and ischemia-induced neurogenesis.

  • Authors : Rahpeymai Y; Institute of Biomedicine, Department of Medical Chemistry and Cell Biology, Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.; Hietala MA

Subjects: Complement C3a/Complement C3a/Complement C3a/*physiology ; Complement C5a/Complement C5a/Complement C5a/*physiology ; Ischemia/Ischemia/Ischemia/*pathology

  • Source: The EMBO journal [EMBO J] 2006 Mar 22; Vol. 25 (6), pp. 1364-74. Date of Electronic Publication: 2006 Feb 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Targeting C3a/C5a receptors inhibits human mesangial cell proliferation and alleviates immunoglobulin A nephropathy in mice.

  • Authors : Zhang Y; Department of Nephrology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Yan X

Subjects: Glomerulonephritis, IGA/Glomerulonephritis, IGA/Glomerulonephritis, IGA/*metabolism ; Kidney/Kidney/Kidney/*pathology ; Receptor, Anaphylatoxin C5a/Receptor, Anaphylatoxin C5a/Receptor, Anaphylatoxin C5a/*metabolism

  • Source: Clinical and experimental immunology [Clin Exp Immunol] 2017 Jul; Vol. 189 (1), pp. 60-70. Date of Electronic Publication: 2017 Apr 10.Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The C3aR promotes macrophage infiltration and regulates ANCA production but does not affect glomerular injury in experimental anti-myeloperoxidase glomerulonephritis.

  • Authors : Dick J; Centre for Inflammatory Diseases, Monash University Department of Medicine, Clayton, Victoria, Australia.; Department of Nephrology, Monash Health, Clayton, Victoria, Australia.

Subjects: Antibodies, Antineutrophil Cytoplasmic/Antibodies, Antineutrophil Cytoplasmic/Antibodies, Antineutrophil Cytoplasmic/*immunology ; Complement C3a/Complement C3a/Complement C3a/*metabolism ; Glomerulonephritis/Glomerulonephritis/Glomerulonephritis/*pathology

  • Source: PloS one [PLoS One] 2018 Jan 09; Vol. 13 (1), pp. e0190655. Date of Electronic Publication: 2018 Jan 09 (Print Publication: 2018).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

C3AR1 as a target for preeclampsia: from bioinformatics and network pharmacology to experimental validation.

  • Authors : Hu Y; Obstetrics and Gynecology Center, Department of Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510280, China.; Department of Obstetrics, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde), Foshan, Guangdong, 528308, China.

Subjects: Pre-Eclampsia*/Pre-Eclampsia*/Pre-Eclampsia*/genetics ; Pre-Eclampsia*/Pre-Eclampsia*/Pre-Eclampsia*/metabolism ; Molecular Docking Simulation*

  • Source: BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2025 Jan 30; Vol. 25 (1), pp. 94. Date of Electronic Publication: 2025 Jan 30.Publisher: BioMed Central Country of Publication: England NLM ID: 100967799 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2393

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  • 1-10 of  160 results for ""Complement C3a""