Search Results

The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation.

• Authors : Lei J; Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, Lübeck, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck- Borstel-Riems Site, University of Lübeck, Lübeck, Germany.

Subjects: Gene Expression Regulation, Viral*; Coronavirus Papain-Like Proteases/Coronavirus Papain-Like Proteases/Coronavirus Papain-Like Proteases/*metabolism ; Peptide Initiation Factors/Peptide Initiation Factors/Peptide Initiation Factors/*metabolism

• Source: The EMBO journal [EMBO J] 2021 Jun 01; Vol. 40 (11), pp. e102277. Date of Electronic Publication: 2021 Apr 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

• Authors : Procacci P.; Macchiagodena M.; Pagliai M. ...

Subjects: COVID-19; SARS-CoV-2; Betacoronavirus

Record details

Interplay of the ubiquitin proteasome system and the innate immune response is essential for the replication of infectious bronchitis virus

• Authors : Tianqi Yu; Chengxiu Fang; Min Liao

Subjects: Proteasome Endopeptidase Complex; animal structures; Interferon-Induced Helicase, IFIH1

• Source: Archives of Virology

Record details

Isolation and genetic characterization of SARS-CoV-2 from Indian patients in a single family without H/O travel abroad

• Authors : Akhilesh Chandra Mishra; Sanjay Lalwani; Vidya A. Arankalle

Subjects: Exonucleases; Viral Plaque Assay; medicine.medical_specialty

• Source: Virus Genes

Record details

The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation

• Authors : Heinrich Leonhardt; Rolf Hilgenfeld; Robert Buschauer

Subjects: Models, Molecular; protein synthesis; Protein Conformation

• Source: The EMBO JournalThe EMBO journal 40(11), e102277 (1-19) (2021). doi:10.15252/embj.2019102277Lei, Jian; Ma-Lauer, Yue; Han, Yinze; Thoms, Matthias; Buschauer, Robert; Jores, Joerg; Thiel,

Record details

Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses

• Authors : Zhenhuan Feng; Ruona Shi; Xiaofei Zhang

Subjects: Ribosomal Proteins; Proteome; viruses

• Source: Genomics, Proteomics & Bioinformatics

Record details

The sprint to solve coronavirus protein structures - and disarm them with drugs

• Authors : Megan Scudellari

Subjects: Azoles; Time Factors; genetic structures

• Source: Nature

Record details

Analysis of Coronavirus Temperature-Sensitive Mutants Reveals an Interplay between the Macrodomain and Papain-Like Protease Impacting Replication and Pathogenesis

• Authors : Robert C. Mettelman; John A Thompson; Amornrat O'Brien

Subjects: Virulence Factors; viruses; Immunology

• Source: Journal of Virology

Record details

Transmissible Gastroenteritis Virus Papain-Like Protease 1 Antagonizes Production of Interferon-β through Its Deubiquitinase Activity

• Authors : Jin Tian; Dafei Liu; Juanjuan Qu

Subjects: 0301 basic medicine; Human coronavirus NL63; Article Subject

• Source: BioMed Research InternationalBioMed Research International, Vol 2017 (2017)

Record details

Identification of protease and ADP-ribose 1″-monophosphatase activities associated with transmissible gastroenteritis virus non-structural protein 3

• Authors : Alexander E. Gorbalenya; John Ziebuhr; Ákos Putics

Subjects: Polyproteins; viruses; medicine.medical_treatment

• Source: Journal of General Virology. 87:651-656

Record details