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Subject : signal transduction

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Academic Journal

Lipopolysaccharide induces acute lung injury and alveolar haemorrhage in association with the cytokine storm, coagulopathy and AT1R/JAK/STAT augmentation in a rat model that mimics moderate and severe Covid-19 pathology.

Authors : Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.; ShamsEldeen AM

Subjects: Signal Transduction*; Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*etiology ; Blood Coagulation Disorders/Blood Coagulation Disorders/Blood Coagulation Disorders/*etiology

Source: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Apr; Vol. 49 (4), pp. 483-491. Date of Electronic Publication: 2022 Feb 09.Publisher: Wiley-Blackwell Country of Publication: Australia NLM ID: 0425076 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2.

Authors : Thangaraju, Kiruphagaran¹; Király, Róbert¹; Demény, Máté A.¹

Subjects: *TRANSGLUTAMINASES; *BLOOD coagulation disorders; *SINGLE nucleotide polymorphisms

Source: PLoS ONE. 3/1/2017, Vol. 12 Issue 3, p1-24. 24p.

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Academic Journal

Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A.

Authors : Gupta, Anurag Kumar¹; Giaglis, Stavros^1,2; Hasler, Paul²

Subjects: *NEUTROPHILS; *EXTRACELLULAR matrix; *INTRACELLULAR calcium

Source: PLoS ONE. May2014, Vol. 9 Issue 5, p1-12. 12p.

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Academic Journal

Thrombin Generation Capacity of Prothrombin Complex Concentrate in an In Vitro Dilutional Model

Authors : Grottke, Oliver¹; Rossaint, Rolf¹; Henskens, Yvonne²

Subjects: *THROMBIN; *PROTHROMBIN; *BLOOD coagulation disorders

Source: PLoS ONE. May2013, Vol. 8 Issue 5, p1-10. 10p.

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The probable role and therapeutic potential of the PI3K/AKT signaling pathway in SARS-CoV-2 induced coagulopathy

Authors : Mohammad Rafi Khezri; Reza Varzandeh; Morteza Ghasemnejad-Berenji

Subjects: Inflammation; PI3K/AKT; Coagulation

Source: Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-10 (2022)Cellular & Molecular Biology Letters

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Lung Epithelial Cell Transcriptional Regulation as a Factor in COVID-19–associated Coagulopathies

Authors : Katherine A. Fitzgerald; Yongzhi Chen; Ethan S. FitzGerald

Subjects: Male; 0301 basic medicine; Pulmonary and Respiratory Medicine

Source: American Journal of Respiratory Cell and Molecular Biology

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The functional role of surface molecules on extracellular vesicles in cancer, autoimmune diseases, and coagulopathy

Authors : Chor Sang Chim; James C. B. Li; Katy C. K. Lam

Subjects: 0301 basic medicine; Functional role; Immunology

Source: Journal of Leukocyte Biology. 108:1565-1573

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Toll‐like receptors 2 and 7 mediate coagulation activation and coagulopathy in murine sepsis

Authors : Jessica Neder; Ping Cui; Lin Zou

Subjects: Male; Inflammation; 030204 cardiovascular system & hematology

Source: J Thromb Haemost

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ALOX12 mutation in a family with dominantly inherited bleeding diathesis

Authors : Hiroko Izumino; Yosuke Sudo; Hiroko Sato

Subjects: 0301 basic medicine; Blood Platelets; medicine.medical_specialty

Source: Journal of human genetics. 66(8)

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Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway?

Authors : Frédéric Lioté; J M Berthelot; Ludovic Drouet

Subjects: 0301 basic medicine; Epidemiology; ACE2

Source: Emerging Microbes & Infectionsarticle-version (VoR) Version of Record

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