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Academic Journal

Copper Oxide Nanoparticles Induce Pulmonary Inflammation and Exacerbate Asthma via the TXNIP Signaling Pathway.

Authors : Kim WI; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.; Pak SW

Subjects: Asthma*/Asthma*/Asthma*/metabolism ; Asthma*/Asthma*/Asthma*/chemically induced ; Asthma*/Asthma*/Asthma*/pathology

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 24; Vol. 25 (21). Date of Electronic Publication: 2024 Oct 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

TXNIP mediated by EZH2 regulated osteogenic differentiation in hBmscs and MC3T3-E1 cells through the modulation of oxidative stress and PI3K/AKT/Nrf2 pathway.

Authors : Zhou W; Department of Orthopedics, Changzhou No. 2 People's Hospital, Changzhou, China.; Zhu C

Subjects: Carrier Proteins*/Carrier Proteins*/Carrier Proteins*/metabolism ; Cell Differentiation* ; Enhancer of Zeste Homolog 2 Protein*/Enhancer of Zeste Homolog 2 Protein*/Enhancer of Zeste Homolog 2 Protein*/metabolism

Source: Connective tissue research [Connect Tissue Res] 2024 Jul; Vol. 65 (4), pp. 293-303. Date of Electronic Publication: 2024 Jun 17.Publisher: Informa Healthcare Country of Publication: England NLM ID: 0365263 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The level of S-glutathionylated protein is a predictor for metastasis in colorectal cancer and correlated with those of Nrf2/Keap1 pathway.

Authors : Chang LC; Department of Pathology, Chang Gung Memorial Hospital, Keelung and Chang Gung University, Keelung, Republic of China.; Fan CW

Subjects: Signal Transduction*; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*metabolism ; Glutathione/Glutathione/Glutathione/*metabolism

Source: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2021 Dec; Vol. 26 (8), pp. 780-787.Publisher: Tayor & Francis Country of Publication: England NLM ID: 9606000 Publication Model: Print Cited Medium: Internet ISSN: 1366-5804

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Academic Journal

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state.

Authors : Trevelin SC; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirão Preto, Brazil.; Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil.

Subjects: Acetophenones/Acetophenones/Acetophenones/*pharmacology ; NADPH Oxidase 2/NADPH Oxidase 2/NADPH Oxidase 2/*metabolism ; NF-kappa B/NF-kappa B/NF-kappa B/*metabolism

Source: Scientific reports [Sci Rep] 2016 Oct 04; Vol. 6, pp. 34581. Date of Electronic Publication: 2016 Oct 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Curcumin relieves paraquat‑induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3‑mediated inflammatory pathway.

Authors : Ren Y; Department of Emergency Medicine, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, P.R. China.; Yang Z

Subjects: Signal Transduction*; Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*etiology ; Acute Lung Injury/Acute Lung Injury/Acute Lung Injury/*metabolism

Source: Molecular medicine reports [Mol Med Rep] 2019 Dec; Vol. 20 (6), pp. 5032-5040. Date of Electronic Publication: 2019 Aug 23.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Increased inflammatory signaling and lethality of influenza H1N1 by nuclear thioredoxin-1.

Authors : Go YM; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia, United States of America.; Kang SM

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Cell Nucleus/Cell Nucleus/Cell Nucleus/*metabolism ; Inflammation/Inflammation/Inflammation/*complications

Source: PloS one [PLoS One] 2011 Apr 15; Vol. 6 (4), pp. e18918. Date of Electronic Publication: 2011 Apr 15.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Thioredoxin-interacting protein links oxidative stress to inflammasome activation.

Authors : Zhou R; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.; Tardivel A

Subjects: Carrier Proteins/Carrier Proteins/Carrier Proteins/*immunology ; Inflammation/Inflammation/Inflammation/*immunology ; Oxidative Stress/Oxidative Stress/Oxidative Stress/*physiology

Source: Nature immunology [Nat Immunol] 2010 Feb; Vol. 11 (2), pp. 136-40. Date of Electronic Publication: 2009 Dec 20.Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Thioredoxin participates in a cell death pathway induced by interferon and retinoid combination.

Authors : Ma X; Greenebaum Cancer Center, Department of Microbiology and Immunology, Molecular and Cellular Biology Program, University of Maryland School of Medicine, Baltimore, Maryland, MD 21201 USA.; Karra S

Subjects: Cell Death* ; Signal Transduction*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*metabolism

Source: Oncogene [Oncogene] 2001 Jun 21; Vol. 20 (28), pp. 3703-15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

Silencing thioredoxin1 exacerbates damage of astrocytes exposed to OGD/R by aggravating apoptosis through the Actin-Ras2-cAMP-PKA pathway.

Authors : Zhu K; a Department of Pathology , The First People's Hospital of Yibin , Yibin , Sichuan , People's Republic of China.; He Q

Subjects: Actins/Actins/Actins/*metabolism ; Apoptosis/Apoptosis/Apoptosis/*physiology ; Astrocytes/Astrocytes/Astrocytes/*metabolism

Source: The International journal of neuroscience [Int J Neurosci] 2018 Jun; Vol. 128 (6), pp. 512-519. Date of Electronic Publication: 2017 Nov 16.Publisher: Informa Healthcare Country of Publication: England NLM ID: 0270707 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Melatonin rescues cardiac thioredoxin system during ischemia-reperfusion injury in acute hyperglycemic state by restoring Notch1/Hes1/Akt signaling in a membrane receptor-dependent manner.

Authors : Yu L; Department of Cardiovascular Surgery, General Hospital of Shenyang Military Area Command, Shenyang, Liaoning, China.; Fan C

Subjects: Hyperglycemia/Hyperglycemia/Hyperglycemia/*complications ; Melatonin/Melatonin/Melatonin/*pharmacology ; Myocardial Reperfusion Injury/Myocardial Reperfusion Injury/Myocardial Reperfusion Injury/*prevention & control

Source: Journal of pineal research [J Pineal Res] 2017 Jan; Vol. 62 (1). Date of Electronic Publication: 2016 Nov 09.Publisher: Wiley Country of Publication: England NLM ID: 8504412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-079X

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Copper Oxide Nanoparticles Induce Pulmonary Inflammation and Exacerbate Asthma via the TXNIP Signaling Pathway.

TXNIP mediated by EZH2 regulated osteogenic differentiation in hBmscs and MC3T3-E1 cells through the modulation of oxidative stress and PI3K/AKT/Nrf2 pathway.

The level of S-glutathionylated protein is a predictor for metastasis in colorectal cancer and correlated with those of Nrf2/Keap1 pathway.

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state.

Curcumin relieves paraquat‑induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3‑mediated inflammatory pathway.

Increased inflammatory signaling and lethality of influenza H1N1 by nuclear thioredoxin-1.

Thioredoxin-interacting protein links oxidative stress to inflammasome activation.

Thioredoxin participates in a cell death pathway induced by interferon and retinoid combination.

Silencing thioredoxin1 exacerbates damage of astrocytes exposed to OGD/R by aggravating apoptosis through the Actin-Ras2-cAMP-PKA pathway.

Melatonin rescues cardiac thioredoxin system during ischemia-reperfusion injury in acute hyperglycemic state by restoring Notch1/Hes1/Akt signaling in a membrane receptor-dependent manner.

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