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Academic Journal

A non-structural protein 1 substitution of dengue virus enhances viral replication by interfering with the antiviral signaling pathway.

  • Authors : Hee JR; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, No.1, University Road, Tainan, 701, Taiwan.; Cheng D

Subjects: Dengue Virus*/Dengue Virus*/Dengue Virus*/genetics ; Dengue Virus*/Dengue Virus*/Dengue Virus*/physiology ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/genetics

  • Source: Journal of biomedical science [J Biomed Sci] 2025 Feb 20; Vol. 32 (1), pp. 25. Date of Electronic Publication: 2025 Feb 20.Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127

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Academic Journal

A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses.

  • Authors : Van Loy B; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.; Pujol E

Subjects: Virus Replication*/Virus Replication*/Virus Replication*/drug effects ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; Endoribonucleases*/Endoribonucleases*/Endoribonucleases*/metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2025 Feb 11; Vol. 21 (2), pp. e1012571. Date of Electronic Publication: 2025 Feb 11 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Avermectins Inhibit Replication of Parvovirus B19 by Disrupting the Interaction Between Importin α and Non-Structural Protein 1.

  • Authors : Alvisi G; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.; Manaresi E

Subjects: Ivermectin*/Ivermectin*/Ivermectin*/pharmacology ; Ivermectin*/Ivermectin*/Ivermectin*/analogs & derivatives ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/metabolism

  • Source: Viruses [Viruses] 2025 Feb 03; Vol. 17 (2). Date of Electronic Publication: 2025 Feb 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

TRIM38 Inhibits Zika Virus by Upregulating RIG-I/MDA5 Pathway and Promoting Ubiquitin-Mediated Degradation of Viral NS3 Protein.

  • Authors : He J; Institute of Basic Medicine, North Sichuan Medical College, Nanchong 637100, China.; Kuang Y

Subjects: Zika Virus*/Zika Virus*/Zika Virus*/physiology ; Zika Virus*/Zika Virus*/Zika Virus*/genetics ; DEAD Box Protein 58*/DEAD Box Protein 58*/DEAD Box Protein 58*/metabolism

  • Source: Viruses [Viruses] 2025 Jan 30; Vol. 17 (2). Date of Electronic Publication: 2025 Jan 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

The Japanese encephalitis virus NS1' protein facilitates virus infection in mosquitoes.

  • Authors : Liu Y; Research Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.; Huang Y

Subjects: Encephalitis Virus, Japanese*/Encephalitis Virus, Japanese*/Encephalitis Virus, Japanese*/physiology ; Encephalitis Virus, Japanese*/Encephalitis Virus, Japanese*/Encephalitis Virus, Japanese*/genetics ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/metabolism

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2025 Jan 27; Vol. 19 (1), pp. e0012823. Date of Electronic Publication: 2025 Jan 27 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Influenza A virus NS2 protein acts on vRNA-resident polymerase to drive the transcription to replication switch.

  • Authors : Zhang L; CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; Department of Infectious Diseases, Shenzhen Children's Hospital, Shenzhen, 518026, China.

Subjects: Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/metabolism ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/genetics ; Virus Replication*/Virus Replication*/Virus Replication*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Jan 24; Vol. 53 (3).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Mutations in chikungunya virus nsP4 decrease viral fitness and sensitivity to the broad-spectrum antiviral 4'-Fluorouridine.

  • Authors : Yin P; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America.; Sobolik EB

Subjects: Chikungunya virus*/Chikungunya virus*/Chikungunya virus*/drug effects ; Chikungunya virus*/Chikungunya virus*/Chikungunya virus*/genetics ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology

  • Source: PLoS pathogens [PLoS Pathog] 2025 Jan 13; Vol. 21 (1), pp. e1012859. Date of Electronic Publication: 2025 Jan 13 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Amino acid T25 in the substrate-binding domain of SARS-CoV-2 nsp5 is involved in viral replication in the mouse lung.

  • Authors : Sugiura Y; Department of Infectious Disease and Host Defense, Graduate School of Medicine, Gunma University, Gunma, Japan.; Shimizu K

Subjects: Virus Replication* ; Lung*/Lung*/Lung*/virology ; Lung*/Lung*/Lung*/metabolism

  • Source: PloS one [PLoS One] 2024 Dec 06; Vol. 19 (12), pp. e0312800. Date of Electronic Publication: 2024 Dec 06 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

ATP synthase subunit ATP5B interacts with TGEV Nsp2 and acts as a negative regulator of TGEV replication.

  • Authors : Wang Y; College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.; China Ministry of Agriculture Key Laboratory of Animal Pathogen Biology, Northeastern Science Inspection Station, Harbin, China.

Subjects: Virus Replication* ; Transmissible gastroenteritis virus*/Transmissible gastroenteritis virus*/Transmissible gastroenteritis virus*/genetics ; Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/Viral Nonstructural Proteins*/metabolism

  • Source: Virulence [Virulence] 2024 Dec; Vol. 15 (1), pp. 2397492. Date of Electronic Publication: 2024 Sep 09.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Antagonism of BST2/Tetherin, a new restriction factor of respiratory syncytial virus, requires the viral NS1 protein.

  • Authors : Marougka K; Université Paris-Saclay, Université de Versailles St. Quentin, M3P, UMR 1173, INSERM, Versailles, France.; Judith D

Subjects: Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/metabolism ; Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/Respiratory Syncytial Virus Infections*/virology ; Respiratory Syncytial Virus, Human*/Respiratory Syncytial Virus, Human*/Respiratory Syncytial Virus, Human*/metabolism

  • Source: PLoS pathogens [PLoS Pathog] 2024 Nov 19; Vol. 20 (11), pp. e1012687. Date of Electronic Publication: 2024 Nov 19 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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  • 1-10 of  2,492 results for ""Viral Nonstructural Proteins""